Results 321 to 330 of about 2,965,907 (391)

Pharmaceutical targeting of OTUB2 sensitizes tumors to cytotoxic T cells via degradation of PD-L1. [PDF]

Nat Commun
Ren W, Xu Z, Chang Y, Ju F, Wu H, Liang Z, Zhao M, Wang N, Lin Y, Xu C, Chen S, Rao Y, Lin C, Yang J, Liu P, Zhang J, Huang C, Xia N.   +17 more
europepmc   +1 more source

Table S2 from Elevated Mast Cell Abundance Is Associated with Enrichment of CCR2⁺ Cytotoxic T Cells and Favorable Prognosis in Lung Adenocarcinoma

Fanfan Fan, Jian Gao, Yue Zhao, Jun Wang, Lu Meng, Jiaqiang Ma, Teng Li, Han Han, Jinglei Lai, Zhendong Gao, Xiongfei Li, Ran Guo, Zhiwei Cao, Yang Zhang, Xiaoming Zhang, Haiquan Chen   +15 more
openalex   +1 more source

Monosaccharide inhibition of cytotoxic T-cell function: demonstration of clone-specific effects.

, 1988
Helen C. O’Neill, Christopher R. Parish   +1 more
openalex  

Tissue-specific abundance of interferon-gamma drives regulatory T cells to restrain DC1-mediated priming of cytotoxic T cells against lung cancer

Immunity, 2023
SUMMARY Local environmental factors influence CD8+ T cell priming in lymph nodes (LN). Here, we sought to understand how factors unique to the tumor-draining mediastinal LN (mLN) impact CD8+ T cell responses toward lung cancer.
Stefani Spranger
exaly   +2 more sources

An HIF-1α/VEGF-A Axis in Cytotoxic T Cells Regulates Tumor Progression

Cancer Cell, 2017
Summary Cytotoxic T cells infiltrating tumors are thought to utilize HIF transcription factors during adaptation to the hypoxic tumor microenvironment. Deletion analyses of the two key HIF isoforms found that HIF-1α, but not HIF-2α, was essential for the
Asis Palazon, David Macias, Pedro Velica   +2 more
exaly   +2 more sources

Imbalance of Regulatory and Cytotoxic SARS-CoV-2-Reactive CD4+ T Cells in COVID-19

Cell, 2020
The contribution of CD4+ T cells to protective or pathogenic immune responses to SARS-CoV-2 infection remains unknown. Here, we present single-cell transcriptomic analysis of >100,000 viral antigen-reactive CD4+ T cells from 40 COVID-19 patients.
Benjamin J Meckiff, Ciro Ramírez-Suástegui, Vicente Fajardo   +2 more
exaly   +2 more sources

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Cytotoxic T-Cells

Methods in Molecular Biology, 2014
E. Ranieri
semanticscholar   +3 more sources

Cytotoxic T cells and immunotherapy

Pediatric Radiology, 1998
Promising immunotherapies for viral infections and malignancies reflect the successful, rapid translation of laboratory findings into clinical practice. Fletcher et al. [1] present imaging studies of Epstein-Barr virus (EBV)-associated lymphomas before and after immunotherapy.
G R, Kitchingman, C, Rooney
openaire   +2 more sources

Cytotoxic T cells clear virus but augment lung pathology in mice infected with respiratory syncytial virus.

Journal of Experimental Medicine, 1988
We have examined the function of class I MHC-restricted cytotoxic T cells in experimental respiratory syncytial virus (RSV) infection of BALB/c mice by transfer of T cell line MJC-A2 and CTL clone E8a into RSV-infected mice.
Peter J M Openshaw
exaly   +2 more sources