Results 1 to 10 of about 358,326 (242)
Cytotoxic Responses Mediated by NK Cells and Cytotoxic T Lymphocytes in Xenotransplantation [PDF]
Transplant InternationalXenotransplantation represents a potential solution to the shortage of organs for transplantation. The recent advancements in porcine genetic modification have addressed hyperacute and acute vascular rejection; however, challenges persist with regard to ...
Viktoriia Galdina +2 more
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Healthy aging—would cytotoxic T lymphocytes stand out? [PDF]
Cell Death Discovery, 2023 Senescent cells (SnCs) accumulate in multiple tissue types with the process of individual aging, hindering tissue renewal and driving multiple aging-related disorders.
Tianyu Zhang, Jinjin Zhang, Shixuan Wang
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Development of classical Hodgkin’s lymphoma in an adult with biallelic STXBP2 mutations [PDF]
Haematologica, 2013 Experimental model systems have delineated an important role for cytotoxic lymphocytes in the immunosurveillance of cancer. In humans, perforin-deficiency has been associated with occurrence of hematologic malignancies.
Maciej Machaczka +7 more
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Neuroinflammation by cytotoxic T-lymphocytes impairs retrograde axonal transport in an oligodendrocyte mutant mouse. [PDF]
PLoS ONE, 2012 Mice overexpressing proteolipid protein (PLP) develop a leukodystrophy-like disease involving cytotoxic, CD8+ T-lymphocytes. Here we show that these cytotoxic T-lymphocytes perturb retrograde axonal transport.
Chi Wang Ip +10 more
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Selective miRNA inhibition in CD8+ cytotoxic T lymphocytes enhances HIV-1 specific cytotoxic responses [PDF]
Frontiers in Immunology, 2022 miRNAs dictate relevant virus-host interactions, offering new avenues for interventions to achieve an HIV remission. We aimed to enhance HIV-specific cytotoxic responses—a hallmark of natural HIV control— by miRNA modulation in T cells.
Nadia Madrid-Elena +23 more
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Rapamycin improves Graves’ orbitopathy by suppressing CD4+ cytotoxic T lymphocytes [PDF]
JCI Insight, 2023 CD4+ cytotoxic T lymphocytes (CTLs) were recently implicated in immune-mediated inflammation and fibrosis progression of Graves’ orbitopathy (GO). However, little is known about therapeutic targeting of CD4+ CTLs.
Meng Zhang +13 more
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IL-27: overclocking cytotoxic T lymphocytes to boost cancer immunotherapy [PDF]
Signal Transduction and Targeted TherapySilvia Dusi +2 more
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Cytotoxic T lymphocytes could contribute in COVID-19-induced passing anosmia
Studia Medyczne, 2021 Several clinical reports have demonstrated a spectrum of neurological manifestations of COVID-19 patients with subsequent post-mortem neuropathological findings. The aim of the case description is to show spotty inflammatory lesions in the olfactory bulb,
Marcin Zaremba +2 more
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Клиническая онкогематология, 2022 Aim. To generate anti-CD87 CAR-T lymphocytes and to assess their in vitro functional activity. Materials & Methods. Т-lymphocytes isolated from healthy donor peripheral blood were transduced with the anti-CD87-CAR, T2A, and FusionRed gene coding ...
M. V. Neklesova +5 more
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Citation: 'cytotoxic T lymphocyte assay' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.13074 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual ...
openaire +2 more sources