Results 91 to 100 of about 905,093 (362)

NKG2D (Natural Killer Group 2, Member D) ligand expression and ameloblastoma recurrence: a retrospective immunohistological pilot study

open access: yesBMC Oral Health
Background/Purpose This retrospective immunohistological pilot study aimed to investigate the influence of natural killer group 2, member D (NKG2D) ligand expression on ameloblastoma recurrence after surgical resection.
Mee-seon Kim   +8 more
doaj   +1 more source

A statistical mechanics approach to autopoietic immune networks [PDF]

open access: yes, 2010
The aim of this work is to try to bridge over theoretical immunology and disordered statistical mechanics. Our long term hope is to contribute to the development of a quantitative theoretical immunology from which practical applications may stem. In order to make theoretical immunology appealing to the statistical physicist audience we are going to ...
arxiv   +1 more source

A novel ligand in lymphocyte-mediated cytotoxicity: expression of the beta subunit of H+ transporting ATP synthase on the surface of tumor cell lines

open access: yesJournal of Experimental Medicine, 1994
Extracellular adenosine triphosphate (eATP) has been suggested to play a role in lymphocyte-induced tumor destruction. We now provide evidence that a protein responsible for ATP synthesis in mitochondria may also play a physiologic role in major ...
Ballabh Das   +4 more
semanticscholar   +1 more source

Annular PIP3 accumulation controls actin architecture and modulates cytotoxicity at the immunological synapse [PDF]

open access: yesJournal of Experimental Medicine, 2013
The immunological synapse formed by a T lymphocyte on the surface of a target cell contains a peripheral ring of filamentous actin (F-actin) that promotes adhesion and facilitates the directional secretion of cytokines and cytolytic factors.
Yoshinori Fukui   +6 more
openaire   +4 more sources

Does Porphyromonas gingivalis truly inhibit the oral carcinogenesis?

open access: yesMolecular Oncology, EarlyView.
 
Chen‐xi Li, Zhong‐cheng Gong
wiley   +1 more source

"A study on Stress, Depression and NK Cytotoxic Potential in Women with Recurrent Spontaneous Abortion "

open access: yesIranian Journal of Allergy, Asthma and Immunology, 2006
It has been recognized that acute and chronic stress has an impact on the immune system. Acute stress may have a stimulating effect on the immune system, while in the case of chronic stress specially depression, the immune system could be down-regulated.
Alireza alib   +4 more
doaj  

Immunity to pathogens taught by specialized human dendritic cell subsets.

open access: yesFrontiers in Immunology, 2015
Dendritic cells (DC) are specialized antigen-presenting cells (APC) that have a key role in immune responses, because they bridge the innate and adaptive arms of the immune system.
Jens A. E. Geginat   +7 more
doaj   +1 more source

Free Radical Scavenging and Cytotoxic Activities of Substituted Pyrimidines [PDF]

open access: yesarXiv, 2020
A library of substituted pyrimidines was synthesized and evaluated for free radical scavenging, and in vitro cytotoxic activity in 3T3 cells. All compounds showed good free radical scavenging activity with IC50 values in the range of 42.9 + 0.31 to 438.3 3.3 {\mu}M as compared to the standard butylated hydroxytoluene having IC50 value of 128.83 2.
arxiv  

Attaining scalable storage-expansion dualism for bioartificial tissues [PDF]

open access: yesarXiv, 2021
The untenable dependence of cryopreservation on cytotoxic cryoprotectants has motivated the mining of biochemical libraries to identify molecular features marking cryoprotectants that may prevent ice crystal growth. It is hypothesized that such molecules may be useful across all temperatures eliminating cellular destruction due to equilibration ...
arxiv  

Loss of proton‐sensing GPR4 reduces tumor progression in mouse models of colon cancer

open access: yesMolecular Oncology, EarlyView.
G protein‐coupled receptor 4 (GPR4) is a pH‐sensing receptor activated by acidic pH. GPR4 expression is increased in patients with inflammatory bowel disease who are at high risk of developing colorectal cancer. In mouse models, loss of GPR4 attenuated tumor progression. This correlated with increased IL2 and natural killer cell activity.
Leonie Perren   +16 more
wiley   +1 more source

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