Results 131 to 140 of about 686,731 (316)

Competition driven cancer immunoediting [PDF]

arXiv, 2014
It is a well-established fact that tumors up-regulate glucose consumption to meet increasing demands for rapidly available energy by switching to purely glycolytic mode of glucose metabolism. What is often neglected is that cytotoxic cells of the immune system also have increased energy demands and also switch to pure glycolysis when they are in an ...
arxiv  

THE SPECIFIC CYTOTOXIC ACTION OF TUBERCULIN IN TISSUE CULTURE [PDF]

, 1931
Joseph D. Aronson
openalex   +1 more source

NFATc1 controls the cytotoxicity of CD8+ T cells

Nature Communications, 2017
Cytotoxic T lymphocytes are effector CD8+ T cells that eradicate infected and malignant cells. Here we show that the transcription factor NFATc1 controls the cytotoxicity of mouse cytotoxic T lymphocytes.
S. Klein-Hessling, K. Muhammad, M. Klein, T. Pusch, Ronald Rudolf, J. Flöter, M. Qureischi, A. Beilhack, M. Vaeth, Carsten Kummerow, Christian S. Backes, Rouven Schoppmeyer, Ulrike Hahn, M. Hoth, T. Bopp, F. Berberich-Siebelt, A. Patra, A. Avots, Nora Müller, A. Schulze, E. Serfling   +20 more
semanticscholar   +1 more source

CD44v, S1PR1, HER3, MET and cancer‐associated amino acid transporters are promising targets for the pancreatic cancers characterized using mAb

FEBS Open Bio, EarlyView.
Novel mAbs could detect cancer‐associated membrane proteins on various type of pancreatic ductal adenocarcinomas (PDAC) by flow cytometry with viable PDAC cells and by immunohistochemistry with PDAC tissues. Results of protein expression were substantiated by mRNA expression by The Cancer Genome Atlas.
Takashi Nakano, Kouki Okita, Shogo Okazaki, Soshi Yoshimoto, Sachiko Masuko, Hideki Yagi, Kazunori Kato, Yoshihisa Tomioka, Kenichi Imai, Yoichi Hamada, Kazue Masuko, Kayoko Shimada‐Takaura, Noriaki Nagai, Hideyuki Saya, Tomio Arai, Toshiyuki Ishiwata, Takashi Masuko   +16 more
wiley   +1 more source

THE CYTOTOXIC ACTION OF IMMUNE GAMMA GLOBULIN AND COMPLEMENT ON KREBS ASCITES TUMOR CELLS [PDF]

, 1959
H. Green, Rebecca Fleischer, P. Barrow, B. Goldberg   +3 more
openalex   +1 more source

Comparative activity of dimethyl fumarate derivative IDMF in three models relevant to multiple sclerosis and psoriasis

FEBS Open Bio, EarlyView.
IDMF is a derivative of dimethyl fumarate (DMF) with a unique therapeutic potential at the intersection of psoriasis and multiple sclerosis. Here, we demonstrate that it compares favorably with DMF and its other derivatives, such as Diroximel, in the zebrafish, microglia, and lymphocyte models.
Yulin He, Guiyi Gong, Geovani Quijas, Simon Ming‐Yuen Lee, Ratan K. Chaudhuri, Krzysztof Bojanowski   +5 more
wiley   +1 more source

Cytotoxicity of Autoclaved Carbohydrate Solutions [PDF]

, 1964
R. J. Berry, Peter Hills, W. Trillwood
openalex   +3 more sources

Identificación preliminar de algunos constituyentes del tallo de Paullinia fuscescens (Sapindaceae) y actividad biológica [PDF]

Avances en Química, 2010
A subfraction α was obtained from stem methanol extract of Paullinia fuscescens, which presented a strong antibacterial activity against Gram positive and Gram negative species besides a strong cytotoxic effect against the crustacean Artemia salina sp ...
Oscar Crescente, José G. Lanza, Diamela Castillo   +2 more
doaj  

Model for Acid-Mediated Tumour Invasion with Chemotherapy Intervention I: Homogeneous Populations [PDF]

arXiv, 2014
The acid-mediation hypothesis, that is, the hypothesis that acid produced by tumours, as a result of aerobic glycolysis, provides a mechanism for invasion, has so far been considered as a relatively closed system. The focus has mainly been on the dynamics of the tumour, normal-tissue, acid and possibly some other bodily components, without considering ...
arxiv  

CYTOTOXIC AGENTS: III, DERIVATIVES OF ETHYLENEIMINE [PDF]

, 1951
J. A. Hendry, R. F. Homer, F. L. Rose, A. L. WALPOLE   +3 more
openalex   +1 more source