Results 261 to 270 of about 686,731 (316)

Highly Extensible Physically Crosslinked Hydrogels for High‐Speed 3D Bioprinting

Advanced Healthcare Materials, EarlyView.
A highly extensible novel hydrogel platform created by facile mixing of cellulose‐based polymer and additives such as non‐ionic surfactants or cyclodextrins is developed. These hydrogels broadly display tunable stiffness, viscoelasticity, stress‐relaxation, and extensional behaviors by simply controlling the composition of the biomaterials.
Ye Eun Song, Noah Eckman, Samya Sen, Carolyn K. Jons, Olivia M. Saouaf, Eric A. Appel   +5 more
wiley   +1 more source

Functionalized Cerium Oxide Nanoparticles Enhance Penetration into Melanoma Spheroids In Vivo through Angiogenesis

Advanced Healthcare Materials, EarlyView.
Melanoma cell spheroid engraftment is optimized in the chicken chorioallantoic membrane overcoming the complexity of other in vivo models. Using this model, greater penetration of cerium oxide nanoparticles (nanoceria) functionalized with heparin in spheroids is observed via enhancement of vascularization than nanoceria alone.
Lu Fu, Joel M. Yong, Robyn Yeh, Florence Bartlett, John M. Whitelock, Megan S. Lord   +5 more
wiley   +1 more source

A Dual‐Layer Hydrogel Barrier Integrating Bio‐Adhesive and Anti‐Adhesive Properties Prevents Postoperative Abdominal Adhesions

Advanced Healthcare Materials, EarlyView.
A new dual‐layer hydrogel barrier for preventing postoperative abdominal adhesions is developed. The inner layer, consisting of polyethyleneimine (PEI) and thioctic acid (TA), enhanced adhesion to moist tissues. The outer layer combines zwitterionic, thermoresponsive hyaluronic acid with anti‐inflammatory epigallocatechin gallate (EGCG) and forms a ...
Mena Asha Krishnan, Olawale A. Alimi, Mitchell Kuss, Tiffany N Razabdouski, Erika A Eksioglu, Bin Duan, Bo Liu   +6 more
wiley   +1 more source

Development of Itaconate Polymers Microparticles for Intracellular Regulation of Pro‐Inflammatory Macrophage Activation

Advanced Healthcare Materials, EarlyView.
This study develops itaconate‐based polymer microparticles (IA‐MPs) for macrophage‐targeted intracellular delivery, overcoming the limitations of traditional itaconate administration. IA‐MPs achieve controlled release through phagocytosis, reducing pro‐inflammatory cytokine expression and reprogramming macrophage metabolism toward glycolysis.
Kaitlyn E. Woodworth, Zachary S.C.S. Froom, Natasha D. Osborne, Christian N. Rempe, Brenden Wheeler, Kyle Medd, Neal I. Callaghan, Huikang Qian, Abhinav P. Acharya, Carlie Charron, Locke Davenport Huyer   +10 more
wiley   +1 more source

Nanohybrid Hydrogel with Dual Functions: Controlled Low‐Temperature Photothermal Antibacterial Activity and Promoted Regeneration for Treating MRSA‐Infected Bone Defects

Advanced Healthcare Materials, EarlyView.
An injectable polydopamine‐based nanohybrid hydrogel integrates controlled low‐temperature photothermal therapy with potent antibacterial efficacy against MRSA while promoting robust bone regeneration. The hydrogel's composite design triggers HSP70 expression, facilitating osteogenesis and efficient bone formation.
Fang Yang, Zewen Shi, Yiwei Hu, Qian Pang, Tianyu Du, Baiyang Song, Jiaqi Zhong, Xiaodong Hu, Weilai Zhu, Junhong Chen, Lin Shi, Xianjun Chen, Qingjiang Pang, Yabin Zhu   +13 more
wiley   +1 more source

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Cytotoxicity of nanoparticles.

Small, 2008
Human exposure to nanoparticles is inevitable as nanoparticles become more widely used and, as a result, nanotoxicology research is now gaining attention.
Nastassja A. Lewinski, V. Colvin, R. Drezek   +2 more
semanticscholar   +3 more sources

Cytotoxicity and cytotoxic molecules in invertebrates [PDF]

BioEssays, 2000
Although lacking the components that characterize the acquired immunity systems of vertebrates, invertebrates nevertheless possess effective general innate immune mechanisms which exhibit striking parallels with those of vertebrates. These innate immune systems include both cellular and humoral elements.
Anthony J. Nappi, Enzo Ottaviani
openaire   +2 more sources

New colorimetric cytotoxicity assay for anticancer-drug screening.

Journal of the National Cancer Institute, 1990
We have developed a rapid, sensitive, and inexpensive method for measuring the cellular protein content of adherent and suspension cultures in 96-well microtiter plates.
P. Skehan, R. Storeng, D. Scudiero, A. Monks, J. Mcmahon, D. Vistica, Jonathan T. Warren, H. Bokesch, S. Kenney, M. Boyd   +9 more
semanticscholar   +1 more source

Cytotoxicity and genotoxicity of silver nanoparticles in human cells.

ACS Nano, 2009
Silver nanoparticles (Ag-np) are being used increasingly in wound dressings, catheters, and various household products due to their antimicrobial activity.
O. Farokhzad, R. Langer, P. Asharani, G. Low, Kah Mun, M. Hande, S. Valiyaveettil   +6 more
semanticscholar   +1 more source

Cytotoxicity of Amalgams

Journal of Dental Research, 1988
The purpose of this study was to compare the relative cytotoxicity of amalgams and to determine whether their toxicity depends upon composition and aging time, by means of a rapid and sensitive in vitro cell culture test. Zinc-containing amalgams showed higher cytotoxicity than did any other amalgams.
Takao Hanawa, Toru Okabe, N.S. Seale, M. Kaga, Jack L. Ferracane   +4 more
openaire   +3 more sources