Results 281 to 290 of about 1,629,625 (355)
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Mechanisms of natural killer cell‐mediated cellular cytotoxicity
Journal of Leukocyte Biology, 2019Cellular cytotoxicity, the ability to kill other cells, is an important effector mechanism of the immune system to combat viral infections and cancer. Cytotoxic T cells and natural killer (NK) cells are the major mediators of this activity.
I. Prager, C. Watzl
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Australian Journal of Experimental Biology and Medical Science, 1981
SummaryWhen mouse spleen cell were cultured in vitro without the deliberate addition of any stimulating cells, T cell‐mediated cytotoxicity was generated which could be detected by lysis of 51Cr‐labelled syngeneic and allogeneic tumour target cells.
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SummaryWhen mouse spleen cell were cultured in vitro without the deliberate addition of any stimulating cells, T cell‐mediated cytotoxicity was generated which could be detected by lysis of 51Cr‐labelled syngeneic and allogeneic tumour target cells.
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Journal of Dental Research, 1988
The purpose of this study was to compare the relative cytotoxicity of amalgams and to determine whether their toxicity depends upon composition and aging time, by means of a rapid and sensitive in vitro cell culture test. Zinc-containing amalgams showed higher cytotoxicity than did any other amalgams.
M, Kaga +4 more
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The purpose of this study was to compare the relative cytotoxicity of amalgams and to determine whether their toxicity depends upon composition and aging time, by means of a rapid and sensitive in vitro cell culture test. Zinc-containing amalgams showed higher cytotoxicity than did any other amalgams.
M, Kaga +4 more
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Mini-Reviews in Medicinal Chemistry, 2007
Various classes of cytotoxic compounds which alkylate cellular thiols are described namely alpha,beta-unsaturated ketones, alpha-methylene-gamma-lactones, azines of Mannich bases, imexon, isothiocyanates, a benzoacronycine as well as activation by thiols prior to alkylation.
Hari N, Pati +3 more
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Various classes of cytotoxic compounds which alkylate cellular thiols are described namely alpha,beta-unsaturated ketones, alpha-methylene-gamma-lactones, azines of Mannich bases, imexon, isothiocyanates, a benzoacronycine as well as activation by thiols prior to alkylation.
Hari N, Pati +3 more
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Glia, 1993
AbstractThe most characteristic property of microglia is their swift activation in response to neuronal stress and their capacity for site‐directed phagocytosis. The transformation of microglia into intrinsic brain macrophages appears to be under strict control and takes place if neuronal and/or terminal degeneration occurs in response to nerve lesion.
R B, Banati +3 more
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AbstractThe most characteristic property of microglia is their swift activation in response to neuronal stress and their capacity for site‐directed phagocytosis. The transformation of microglia into intrinsic brain macrophages appears to be under strict control and takes place if neuronal and/or terminal degeneration occurs in response to nerve lesion.
R B, Banati +3 more
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Fluorinated Nanocarbons Cytotoxicity
Chemistry – A European Journal, 2015AbstractAs the research in nanotechnology progresses, there will eventually be an influx in the number of commercial products containing different types of nanomaterials. This phenomenon might damage our health and environment if the nanomaterials used are found to be toxic and they are released into the waters when the products degrade. In this study,
Wei Zhe, Teo +3 more
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1999
Cytotoxic T lymphocytes (CTLs) represent the body’s primary line of defence against virus-infected and tumourigenic cells, and may play a role in autoimmune diseases and organ transplant rejection. CTLs are able to carry out their essential functions due to their ability to specifically recognize and destroy “foreign” cells.
A J, Darmon +2 more
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Cytotoxic T lymphocytes (CTLs) represent the body’s primary line of defence against virus-infected and tumourigenic cells, and may play a role in autoimmune diseases and organ transplant rejection. CTLs are able to carry out their essential functions due to their ability to specifically recognize and destroy “foreign” cells.
A J, Darmon +2 more
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Cytotoxic Hammerhead Ribozymes
Antisense and Nucleic Acid Drug Development, 1999Small catalytic RNA molecules of the hammerhead ribozyme type were found to have cytotoxic effects unrelated to their intended activity. An expression library of ribozyme sequence variants was constructed in a recA-deficient strain of Escherichia coli such that individual library members differed in regions designed to form base pairs with human ...
R, Levitz +9 more
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Acta Odontologica Scandinavica, 1980
The present summary and the following papers (I-VIII) have been submitted in partial fulfilment of the requirements for the degree of Doctor Odontologiae at the University of Oslo.Effect of sodium fluoride on LS cells. (Coauthors: Jan K. Hongslo and Jon Jonsen) J. Dent. Res.
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The present summary and the following papers (I-VIII) have been submitted in partial fulfilment of the requirements for the degree of Doctor Odontologiae at the University of Oslo.Effect of sodium fluoride on LS cells. (Coauthors: Jan K. Hongslo and Jon Jonsen) J. Dent. Res.
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