Results 271 to 280 of about 686,731 (316)
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Cytotoxicity of microglia

Glia, 1993
AbstractThe most characteristic property of microglia is their swift activation in response to neuronal stress and their capacity for site‐directed phagocytosis. The transformation of microglia into intrinsic brain macrophages appears to be under strict control and takes place if neuronal and/or terminal degeneration occurs in response to nerve lesion.
Jochen Gehrmann   +3 more
openaire   +2 more sources

Syringic acid triggers reactive oxygen species–mediated cytotoxicity in HepG2 cells

Human and Experimental Toxicology, 2019
Hepatocellular carcinoma is the second most common cause of cancer death in the world and its incidence has dramatically increased worldwide in the past two decades.
S. Gheena, D. Ezhilarasan
semanticscholar   +1 more source

Mechanisms of natural killer cell‐mediated cellular cytotoxicity

Journal of Leukocyte Biology, 2019
Cellular cytotoxicity, the ability to kill other cells, is an important effector mechanism of the immune system to combat viral infections and cancer. Cytotoxic T cells and natural killer (NK) cells are the major mediators of this activity.
I. Prager, C. Watzl
semanticscholar   +1 more source

Betel cytotoxicity

Journal of Ethnopharmacology, 1989
An attempt to summarise the phytochemical composition of the betel quid, formation of N-nitrosation products during chewing, results of carcinogenicity and mutagenicity studies and the relationship between betel chewing and submucous fibrosis have been made from presently available literature.
S, Sen, G, Talukder, A, Sharma
openaire   +2 more sources

Cytotoxicity of fluoride

Acta Odontologica Scandinavica, 1980
The present summary and the following papers (I-VIII) have been submitted in partial fulfilment of the requirements for the degree of Doctor Odontologiae at the University of Oslo.Effect of sodium fluoride on LS cells. (Coauthors: Jan K. Hongslo and Jon Jonsen) J. Dent. Res.
openaire   +3 more sources

Cytotoxic proteins

Current Opinion in Biotechnology, 1992
Cytotoxic proteins, which enter eukaryotic cells and catalytically inactivate protein synthesis, are being increasingly studied using a combination of molecular biology, cell biology and structural approaches. The creation of genetically engineered fusions with alternative cell-binding ligands paves the way for tailor-made, cell-type-specific killing ...
L M, Roberts, J M, Lord
openaire   +2 more sources

Phylogeny of cytotoxicity

Endeavour, 1980
Abstract The life of animals can be sustained only if the cellular environment can be closely controlled. Elaborate processes have, therefore, been evolved to detect and eliminate foreign material in the body, including tumour cells. An understanding of these processes is of great medical importance.
openaire   +3 more sources

Sensitivity of cytotoxic T cells to T-cell mediated cytotoxicity

Nature, 1974
LYMPHOID cells sensitised against alloantigens can lyse in vitro target cells bearing these alloantigens1,2. In most of the experimental systems using in vivo sensitised cells, T cells (thymus-dependent lymphocytes) are both necessary3 and sufficient4,5 for induction of target cell lysis.
openaire   +2 more sources

Prevention of cytotoxicity and inhibition of intercellular communication by antioxidant catechins isolated from Chinese green tea.

Carcinogenesis, 1989
An antioxidant fraction of Chinese green tea (green tea antioxidant; GTA), containing several catechins, has been previously shown to inhibit 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced tumor promotion in mouse skin.
R. Ruch, Shu-jun Cheng, J. Klaunig
semanticscholar   +1 more source

Calreticulin in Cytotoxic Lymphocyte-Mediated Cytotoxicity

2003
New functions are implicated for calreticulin, based on its release from cytotoxic NK and T cells. Calreticulin is the only one of six “KDEL” (Lys-Asp-Glu-Leu carboxy terminal) endoplasmic reticulum chaperone proteins present in cytotoxic granules of these lymphocytes.
Dorothy Hudig, Reza Karimi
openaire   +2 more sources

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