Results 281 to 290 of about 1,197,953 (344)
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Journal of Ethnopharmacology, 1989
An attempt to summarise the phytochemical composition of the betel quid, formation of N-nitrosation products during chewing, results of carcinogenicity and mutagenicity studies and the relationship between betel chewing and submucous fibrosis have been made from presently available literature.
S, Sen, G, Talukder, A, Sharma
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An attempt to summarise the phytochemical composition of the betel quid, formation of N-nitrosation products during chewing, results of carcinogenicity and mutagenicity studies and the relationship between betel chewing and submucous fibrosis have been made from presently available literature.
S, Sen, G, Talukder, A, Sharma
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Current Opinion in Biotechnology, 1992
Cytotoxic proteins, which enter eukaryotic cells and catalytically inactivate protein synthesis, are being increasingly studied using a combination of molecular biology, cell biology and structural approaches. The creation of genetically engineered fusions with alternative cell-binding ligands paves the way for tailor-made, cell-type-specific killing ...
L M, Roberts, J M, Lord
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Cytotoxic proteins, which enter eukaryotic cells and catalytically inactivate protein synthesis, are being increasingly studied using a combination of molecular biology, cell biology and structural approaches. The creation of genetically engineered fusions with alternative cell-binding ligands paves the way for tailor-made, cell-type-specific killing ...
L M, Roberts, J M, Lord
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Cytotoxicity of nanoparticles.
Small, 2008AbstractHuman exposure to nanoparticles is inevitable as nanoparticles become more widely used and, as a result, nanotoxicology research is now gaining attention. However, while the number of nanoparticle types and applications continues to increase, studies to characterize their effects after exposure and to address their potential toxicity are few in
Nastassja A. Lewinski +2 more
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Cytotoxicity and cytotoxic molecules in invertebrates
BioEssays, 2000Although lacking the components that characterize the acquired immunity systems of vertebrates, invertebrates nevertheless possess effective general innate immune mechanisms which exhibit striking parallels with those of vertebrates. These innate immune systems include both cellular and humoral elements.
A J, Nappi, E, Ottaviani
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Syringic acid triggers reactive oxygen species–mediated cytotoxicity in HepG2 cells
Human and Experimental Toxicology, 2019Hepatocellular carcinoma is the second most common cause of cancer death in the world and its incidence has dramatically increased worldwide in the past two decades.
S. Gheena, D. Ezhilarasan
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Mechanisms of natural killer cell‐mediated cellular cytotoxicity
Journal of Leukocyte Biology, 2019Cellular cytotoxicity, the ability to kill other cells, is an important effector mechanism of the immune system to combat viral infections and cancer. Cytotoxic T cells and natural killer (NK) cells are the major mediators of this activity.
I. Prager, C. Watzl
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Australian Journal of Experimental Biology and Medical Science, 1981
SummaryWhen mouse spleen cell were cultured in vitro without the deliberate addition of any stimulating cells, T cell‐mediated cytotoxicity was generated which could be detected by lysis of 51Cr‐labelled syngeneic and allogeneic tumour target cells.
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SummaryWhen mouse spleen cell were cultured in vitro without the deliberate addition of any stimulating cells, T cell‐mediated cytotoxicity was generated which could be detected by lysis of 51Cr‐labelled syngeneic and allogeneic tumour target cells.
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Journal of Dental Research, 1988
The purpose of this study was to compare the relative cytotoxicity of amalgams and to determine whether their toxicity depends upon composition and aging time, by means of a rapid and sensitive in vitro cell culture test. Zinc-containing amalgams showed higher cytotoxicity than did any other amalgams.
M, Kaga +4 more
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The purpose of this study was to compare the relative cytotoxicity of amalgams and to determine whether their toxicity depends upon composition and aging time, by means of a rapid and sensitive in vitro cell culture test. Zinc-containing amalgams showed higher cytotoxicity than did any other amalgams.
M, Kaga +4 more
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Mini-Reviews in Medicinal Chemistry, 2007
Various classes of cytotoxic compounds which alkylate cellular thiols are described namely alpha,beta-unsaturated ketones, alpha-methylene-gamma-lactones, azines of Mannich bases, imexon, isothiocyanates, a benzoacronycine as well as activation by thiols prior to alkylation.
Hari N, Pati +3 more
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Various classes of cytotoxic compounds which alkylate cellular thiols are described namely alpha,beta-unsaturated ketones, alpha-methylene-gamma-lactones, azines of Mannich bases, imexon, isothiocyanates, a benzoacronycine as well as activation by thiols prior to alkylation.
Hari N, Pati +3 more
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Glia, 1993
AbstractThe most characteristic property of microglia is their swift activation in response to neuronal stress and their capacity for site‐directed phagocytosis. The transformation of microglia into intrinsic brain macrophages appears to be under strict control and takes place if neuronal and/or terminal degeneration occurs in response to nerve lesion.
R B, Banati +3 more
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AbstractThe most characteristic property of microglia is their swift activation in response to neuronal stress and their capacity for site‐directed phagocytosis. The transformation of microglia into intrinsic brain macrophages appears to be under strict control and takes place if neuronal and/or terminal degeneration occurs in response to nerve lesion.
R B, Banati +3 more
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