Results 291 to 300 of about 1,578,267 (386)

Alleviation of Aging‐Related Hallmarks in a Mouse Model of Progeria via a Nanoparticle‐Based Artificial Transcription Factor

Advanced Functional Materials, EarlyView.
Oct4‐nanoscript, a biomimetic nanoparticle‐based artificial transcription factor, precisely regulates cellular rejuvenation by activating Oct4 target genes, restoring epigenetic marks, and reducing DNA damage. In a progeria model, it effectively rescued aging‐associated pathologies and extended lifespan.
Hongwon Kim, Junyeop Kim, Euiyeon Lee, Brandon Conklin, Yannan Hou, Sumin Kim, Yerim Hwang, Ki‐Bum Lee, Jongpil Kim   +8 more
wiley   +1 more source

Evaluating Naphthalene-Modified Metallosalen Complexes as Anticancer Agents. [PDF]

J Med Chem
Acosta-Mercado J, Oliveras-Alsina A, Marcano-Maiz AI, Rivera-Torres AP, Cordero-Gimenez KT, Malavez-Cajigas S, Bayro MJ, Ramos-Benitez MJ, Piñero Cruz DM.   +8 more
europepmc   +1 more source

Relation Between the Cytotoxic Action of Metals and the Coagulation of Medium (Supplement)

, 1960
川原 春幸, 太田 文正, 渡辺 清, 渡辺 博土, 友田 亮生, 押鐘 功   +5 more
openalex   +2 more sources

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

Advanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Flow‐Induced Vascular Remodeling on‐Chip: Implications for Anti‐VEGF Therapy

Advanced Functional Materials, EarlyView.
Flow‐induced vascular remodeling plays a critical role in network stabilization and function. Using a vasculature‐on‐chip system, this study reveals how physiological VEGF levels and flow affect vascular remodeling and provides insights into tumor vessel normalization.
Fatemeh Mirzapour‐Shafiyi, Elias Huber, Leonie Karr, Johnny Tong, Andreas Richard Bausch, Friedrich Christian Simmel, Karen Alim   +6 more
wiley   +1 more source

Comparative Analysis of Different Root Canal Sealers' Cytotoxicity to Human Cells.

J Pharm Bioallied Sci
Arya A, Hema M, Uikey G, Rai A, Suresh S, Banik A.   +5 more
europepmc   +1 more source

NKp30: A Key Membrane Molecule in the Fight Against Cancer and Infection. [PDF]

FASEB J
Shao Y, Zhang Y, Cao J, He J, He Q, Lei Y, Tang N, Zhou Y.   +7 more
europepmc   +1 more source

Bacteria‐Derived Extracellular Vesicle as A “Trojan Horse” for Selective M1 Macrophage‐Targeting in A Multi‐Cellular Entanglement Environment

Advanced Functional Materials, EarlyView.
The temporary transition of macrophages from a pro‐inflammatory phenotype of macrophages (M1) to an anti‐inflammatory phenotype of macrophages (M2) is crucial for tissue repair and regeneration processes. Bacterial outer membrane vesicles (OMVs) are utilized as a “trojan horse” for specific M1 macrophage‐targeting and anti‐inflammatory drug delivery ...
Donglin Cai, Zhelun Li, Wendong Gao, Yuqing Mu, Jiaying Liu, Yufeng Zhang, Xiaohan Mei, Jingjing Quan, Lan Xiao, Yin Xiao   +9 more
wiley   +1 more source

Ultrasound-Mediated Drug Diffusion, Uptake, and Cytotoxicity in a Glioblastoma 3D Tumour Sphere Model. [PDF]

Cells
Wanigasekara J, Mondala JRM, Cullen PJ, Tiwari BK, Kinsella GK, Curtin JF.   +5 more
europepmc   +1 more source

Cytotoxic antibody response to skin allografts in calves: effects of extracorporeal irradiation of lymph

, 1969
D D Joel, A. D. Chanana, E.P. Cronkite, L M Shiffer   +3 more
openalex   +1 more source