Estimation of In-Vitro Free Radical Scavenging and Cytotoxic Activities of Thiocarbohydrazones Derivatives [PDF]
Objective: To investigate free radical scavenging potential of thiocarbohydrazones derivatives for the discovery of antioxidant compounds of synthetic origin. Method: Eighteen thiocarbohydrazones derivatives were screened for antioxidant activities by using in vitro radical inhibition assay.
arxiv
A Nearest-Neighbor Based Nonparametric Test for Viral Remodeling in Heterogeneous Single-Cell Proteomic Data [PDF]
An important problem in contemporary immunology studies based on single-cell protein expression data is to determine whether cellular expressions are remodeled post infection by a pathogen. One natural approach for detecting such changes is to use non-parametric two-sample statistical tests.
arxiv
In vitro evaluation of a novel Mg-Sn-Ge ternary alloy for orthopedic applications [PDF]
Magnesium (Mg) and its alloys have attracted considerable attention owing to their excellent biodegradable properties and biocompatibility. Novel Mg-Sn-Ge ternary Mg alloys were developed as potential biodegradable materials for orthopedic applications because of their alloying elements naturally present in humans.
arxiv
A Beginners Guide to Systems Simulation in Immunology [PDF]
Some common systems modelling and simulation approaches for immune problems are Monte Carlo simulations, system dynamics, discrete-event simulation and agent-based simulation. These methods, however, are still not widely adopted in immunology research.
arxiv
Classifying patient voice in social media data using neural networks: A comparison of AI models on different data sources and therapeutic domains [PDF]
It is essential that healthcare professionals and members of the healthcare community can access and easily understand patient experiences in the real world, so that care standards can be improved and driven towards personalised drug treatment. Social media platforms and message boards are deemed suitable sources of patient experience information, as ...
arxiv
ICAM-1-mediated cell-cell adhesion is essential for various immunologic functions, including non-MHC-restricted cytotoxicity. The present study was designed to establish whether shedding of ICAM-1 from melanoma cells occurred and to characterize the ...
Jürgen C. Becker+4 more
semanticscholar +1 more source
Strange Attractor in Immunology of Tumor Growth [PDF]
The time delayed cytotoxic T-lymphocyte response on the tumor growth has been developed on the basis of discrete approximation (2-dimensional map). The growth kinetic has been described by logistic law with growth rate being the bifurcation parameter.
arxiv
Blood lymphocytes of patients with solid tumors were assayed for cytotoxicity against autologous and allogeneic primary tumor cells. The lymphocytes killed autologous tumor cells in 7 of 25 cases (28%) and allogeneic tumor cells in 2 of 37 tests (5 ...
S. Argov, S. Einhorn, E. Klein
semanticscholar +1 more source
Mathematical analysis and simulation study of a phase-field model of prostate cancer growth with chemotherapy and antiangiogenic therapy effects [PDF]
Cytotoxic chemotherapy is a common treatment for advanced prostate cancer. These tumors are also known to rely on angiogenesis, i.e., the growth of local microvasculature via chemical signaling produced by the tumor. Thus, several clinical studies have been investigating antiangiogenic therapy for advanced prostate cancer, either as monotherapy or ...
arxiv
Antibody-dependent cellular cytotoxicity and skin disease.
Antibody dependent cellular cytotoxicity (ADCC) is a recently described mechanism of immunologic lysis in which cellular targets sensitized by specific antibodies are efficiently and selectively lysed by Fc receptor (FcR) bearing nonspecific effectors ...
David A. Norris, L. Lee
semanticscholar +1 more source