Results 101 to 110 of about 445,868 (362)

The cytotoxic effect of pinostrobin fingerroot (boesenbergia pandurata)on the culture of hela cells

JKKI (Jurnal Kedokteran dan Kesehatan Indonesia), 2016
Background : Cancer is one of the leading causes of death worldwide, therefore struggles to find more effective treatment and prevention is needed. Several studies has been performed using natural ingredients, one of which is Temu Kunci (B.
Rosmelia Rosmelia, Betty Ekawati Suryaningsih, Hady Anshory, Yohanes Widodo Wirohadidjojo   +3 more
doaj   +1 more source

Superparamagnetic iron oxide nanoparticles conjugated with doxorubicin for targeting breast cancer [PDF]

arXiv, 2019
Development of the next generations of cancer therapy modalities is currently a crucial requirement of oncology. Advances in nanotechnology are bringing us closer to the development of dual and multifunctional nanoparticles that are challenging the traditional distinction between diagnostic and treatment agents. The chase of innovative, multifunctional,
arxiv  

Comparison of 20nm silver nanoparticles synthesized with and without a gold core: Structure, dissolution in cell culture media, and biological impact on macrophages [PDF]

, 2015
Widespread use of silver nanoparticles raises questions of environmental and biological impact. Many synthesis approaches are used to produce pure silver and silver-shell gold-core particles optimized for specific applications.
Baer, DR, Chen, S, Engelhard, MH, Kodali, V, Liu, C, Munusamy, P, Porter, AE, Ryan, MP, Smith, JN, Thrall, BD, Wang, C   +10 more
core   +1 more source

Classification of acute myeloid leukemia based on multi‐omics and prognosis prediction value

Molecular Oncology, EarlyView.
The Unsupervised AML Multi‐Omics Classification System (UAMOCS) integrates genomic, methylation, and transcriptomic data to categorize AML patients into three subtypes (UAMOCS1‐3). This classification reveals clinical relevance, highlighting immune and chromosomal characteristics, prognosis, and therapeutic vulnerabilities.
Yang Song, Zhe Wang, Guangji Zhang, Jiangxue Hou, Kaiqi Liu, Shuning Wei, Yan Li, Chunlin Zhou, Dong Lin, Min Wang, Hui Wei, Jianxiang Wang, Tao Cheng, Yingchang Mi   +13 more
wiley   +1 more source

Biological activities of ethanolic extracts from deep-sea antarctic marine sponges [PDF]

, 2013
We report on the screening of ethanolic extracts from 33 deep-sea Antarctic marine sponges for different biological activities. We monitored hemolysis, inhibition of acetylcholinesterase, cytotoxicity towards normal and transformed cells and growth ...
Ambrožič Avguštin, Jerneja, Batista, Urška, Janussen, Dorte, Kauferstein, Silke, Kosmina, Rok, Mebs, Dietrich, Sepčić, Kristina, Strugar, Gašper, Turk, Tom, Čivović, Sandra   +9 more
core   +3 more sources

TOMM20 as a driver of cancer aggressiveness via oxidative phosphorylation, maintenance of a reduced state, and resistance to apoptosis

Molecular Oncology, EarlyView.
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam, Megan E. Roche, Zhao Lin, Diana Whitaker‐Menezes, Victor Diaz‐Barros, Eurico Serrano, Maria Paula Martinez Cantarin, Nancy J. Philp, Atrayee Basu Mallick, Ubaldo Martinez‐Outschoorn   +9 more
wiley   +1 more source

Controlling disinfection byproducts from treated wastewater using adsorption with granular activated carbon: Impact of pre-ozonation and pre-chlorination

Water Research X, 2020
This study measured chlorine- and chloramine-reactive precursors using formation potential (FP) tests of nine U.S. Environmental Protection Agency (EPA) regulated and 57 unregulated disinfection byproducts (DBPs) in tertiary-filtered wastewater before ...
Edgard M. Verdugo, Mac Gifford, Caitlin Glover, Amy A. Cuthbertson, Rebecca A. Trenholm, Susana Y. Kimura, Hannah K. Liberatore, Susan D. Richardson, Benjamin D. Stanford, R. Scott Summers, Eric R.V. Dickenson   +10 more
doaj  

Chloroquine-enhanced gene delivery mediated by carbon nanotubes [PDF]

, 2011
Polyethyleneimine-coated double-walled carbon nanotubes (DWCNTs) were used for dual gene and drug delivery, after loading the DWCNTs with the drug chloroquine, a lysosomotropic compound that is able to promote escape from the lysosomal compartment ...
Borowiak-Palen, Brigitte Soula, Carmen Tilmacîu, Cheng, Chu, Davis, Emmanuel Flahaut, Flahaut, Flahaut, Flahaut, Flahaut, Hampel, Hasan, Hatefi, Heister, Helen M. Coley, Hilder, Hilder, Jeynes, Johnjoe McFadden, Jorge, Kam, Kam, Klumpp, Kollen, Kuznetsova, Kwok, Lago, Lechardeur, Lechardeur, Lin, Miao, Mouchet, Neves, Puech, S. Ravi P. Silva, Salvador-Morales, Sanz, Shao, Shao, Thamavaranukup, Tîlmaciu, Vanesa Sanz, Viola, Wattiaux   +44 more
core   +2 more sources

Thermal proteome profiling and proteome analysis using high‐definition mass spectrometry demonstrate modulation of cholesterol biosynthesis by next‐generation galeterone analog VNPP433‐3β in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Elevated level of cholesterol is positively correlated to prostate cancer development and disease severity. Cholesterol‐lowering drugs, such as statins, are demonstrated to inhibit prostate cancer. VNPP433‐3β interrupts multiple signaling and metabolic pathways, including cholesterol biosynthesis, AR‐mediated transcription of several oncogenes, mRNA 5′
Retheesh S. Thankan, Elizabeth Thomas, Mehari M. Weldemariam, Puranik Purushottamachar, Weiliang Huang, Maureen A. Kane, Yuji Zhang, Nicholas Ambulos, Bi‐Dar Wang, David Weber, Vincent C. O. Njar   +10 more
wiley   +1 more source

Important Parameters in Cytotoxicity Testing of Nanoparticles [PDF]

Scientia Pharmaceutica, 2010
Background: The use of nano-sized materials (NMs) offers exciting new options in technical and medical applications. Adverse effects on cells and organs, however, [...]
Eva Roblegg, Thomas R. Pieber, Eleonore Fröhlich, Claudia Meindl   +3 more
openaire   +1 more source