Results 121 to 130 of about 435,610 (360)

Fe3O4@astragalus polysaccharide core-shell nanoparticles for iron deficiency anemia therapy and magnetic resonance imaging in vivo [PDF]

arXiv, 2018
Fe3O4@astragalus polysaccharide core-shell nanoparticles (Fe3O4@APS NPs) were demonstrated to be an efficient therapeutic drug for treating iron deficiency anemia (IDA) in vivo. The Fe3O4@APS NPs have been synthesized using a two steps approach involving hydrothermal synthesis and subsequent esterification.
arxiv  

Comparison of cytotoxicity of IQOS aerosols to smoke from Marlboro Red and 3R4F reference cigarettes. [PDF]

, 2019
This study compared the cytotoxicity of IQOS aerosols to smoke from Marlboro Red (MR) and 3R4F reference cigarettes. Aerosol/smoke solutions were tested as the gas vapor phase (GVP), particulate phase (total particulate matter or TPM), or whole aerosol ...
Davis, Barbara, Talbot, Prue, To, Vivian
core   +1 more source

Pseudomonas aeruginosa pilin activates the inflammasome [PDF]

, 2011
IL-1 beta is produced from inactive pro-IL-1 beta by activation of caspase-1 brought about by a multi-subunit protein platform called the inflammasome. Many bacteria can trigger inflammasome activity through flagellin activation of the host protein NLRC4.
Agostini, Andersen-Nissen, Arora, Auron, Bergsbaken, Bird, Bitter, Case, Choi, Cornelis, Craig, Dinarello, Evans, Franchi, Franchi, Franchi, Hahn, Hazes, Hsu, Johnson, Kanneganti, Kus, Lightfield, Lindestam Arlehamn, Liu, Marathe, Mariathasan, Mariathasan, Martinon, Martinon, Mattick, Miao, Miao, Miao, Murray, Muruve, Neyt, O'Neill, Perkins, Pier, Proft, Sato, Sato, Sawa, Schroeder, Semmler, Smedley, Sutterwala, Sutterwala, Thornberry, Ting, Vallis, von Götz, Ye, Yu   +54 more
core   +1 more source

A large‐scale retrospective study in metastatic breast cancer patients using circulating tumour DNA and machine learning to predict treatment outcome and progression‐free survival

Molecular Oncology, EarlyView.
There is an unmet need in metastatic breast cancer patients to monitor therapy response in real time. In this study, we show how a noninvasive and affordable strategy based on sequencing of plasma samples with longitudinal tracking of tumour fraction paired with a statistical model provides valuable information on treatment response in advance of the ...
Emma J. Beddowes, Mario Ortega Duran, Solon Karapanagiotis, Alistair Martin, Meiling Gao, Riccardo Masina, Ramona Woitek, James Tanner, Fleur Tippin, Justine Kane, Jonathan Lay, Anja Brouwer, Stephen‐John Sammut, Suet‐Feung Chin, Davina Gale, Dana W. Y. Tsui, Sarah‐Jane Dawson, Nitzan Rosenfeld, Maurizio Callari, Oscar M. Rueda, Carlos Caldas   +20 more
wiley   +1 more source

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Anti-Candida, Anti-Enzyme Activity and Cytotoxicity of 3,5-Diaryl-4,5-dihydro-1H-pyrazole-1-carboximidamides

Molecules, 2014
Because of the need for more effective and less harmful antifungal therapies, and interest in the synthesis of new carboximidamides, the goal of this study was to determine the antifungal and anti-enzyme activities of some new pyrazole carboximidamides ...
Simone Oliveira, Lucas Pizzuti, Frank Quina, Alex Flores, Rafael Lund, Claiton Lencina, Bruna S. Pacheco, Claudio M. P. de Pereira, Evandro Piva   +8 more
doaj   +1 more source

In-Vitro Growth Kinetics of Mesenchymal Stem Cells in Cytotoxicity Tests Using Low-Diluted Viscum Album. [PDF]

Homeopathy, 2023
Valle ACV, Brunel HDSS, Dallago BSL, Rodrigues LS, Malard PF, da Costa RA, Rossetto R, de Andrade RV.   +7 more
europepmc   +1 more source

Improvement on corrosion resistance and biocompability of ZK60 magnesium alloy by carboxyl ion implantation [PDF]

arXiv, 2019
Magnesium alloys have been considered to be potential biocompatible metallic materials. Further improvement on the anti-corrosion is expected to make this type of materials more suitable for biomedical applications in the fields of orthopedics, cardiovascular surgery and others.
arxiv  

Application of Chemiluminescent Assay in Cytotoxicity Tests

Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi), 1997
This study showed that chemiluminescent (CL) assay is superior to Giemsa staining assay or MTT reduction assay in sensitivity and rapidity for detection of the cytotoxic effects of four compounds (phenobarbital sodium, theophyllin, propranolol and thioridazine).
Kazuko Kitamura, Yoshihide Suwa
openaire   +3 more sources

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source