In Vitro Toxicity Assessment of Stilbene Extract for Its Potential Use as Antioxidant in the Wine Industry [PDF]
, 2019 The reduction of sulfur dioxide in wine is a consumer’s demand, considering the allergic effects that may occur in people who are sensitive to it. Stilbenes are candidates of great interest for this purpose because of their antioxidant/antimicrobial ...
Cantos Villar, Emma +5 more
core +2 more sources
Ubiquitination of transcription factors in cancer: unveiling therapeutic potential
Molecular Oncology, EarlyView.In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley +1 more source
Molecules, 2014 Because of the need for more effective and less harmful antifungal therapies, and interest in the synthesis of new carboximidamides, the goal of this study was to determine the antifungal and anti-enzyme activities of some new pyrazole carboximidamides ...
Simone Oliveira +8 more
doaj +1 more source
Fe3O4@astragalus polysaccharide core-shell nanoparticles for iron deficiency anemia therapy and magnetic resonance imaging in vivo [PDF]
arXiv, 2018 Fe3O4@astragalus polysaccharide core-shell nanoparticles (Fe3O4@APS NPs) were demonstrated to be an efficient therapeutic drug for treating iron deficiency anemia (IDA) in vivo. The Fe3O4@APS NPs have been synthesized using a two steps approach involving hydrothermal synthesis and subsequent esterification.
arxiv
In-Vitro Growth Kinetics of Mesenchymal Stem Cells in Cytotoxicity Tests Using Low-Diluted Viscum Album. [PDF]
Homeopathy, 2023 Valle ACV +7 more
europepmc +1 more source
Application of Chemiluminescent Assay in Cytotoxicity Tests
Food Hygiene and Safety Science (Shokuhin Eiseigaku Zasshi), 1997 This study showed that chemiluminescent (CL) assay is superior to Giemsa staining assay or MTT reduction assay in sensitivity and rapidity for detection of the cytotoxic effects of four compounds (phenobarbital sodium, theophyllin, propranolol and thioridazine).
Kazuko Kitamura, Yoshihide Suwa
openaire +3 more sources
New trends for metal complexes with anticancer activity [PDF]
, 2008 Medicinal inorganic chemistry can exploit the unique properties of metal ions for the design of new drugs. This has, for instance, led to the clinical application of chemotherapeutic agents for cancer treatment, such as cisplatin. The use of cisplatin is,
Ang +56 more
core +1 more source
Targeted protein degradation in oncology: novel therapeutic opportunity for solid tumours?
Molecular Oncology, EarlyView.Current anticancer therapies are limited by the occurrence of resistance and undruggability of most proteins. Targeted protein degraders are novel, promising agents that trigger the selective degradation of previously undruggable proteins through the recruitment of the ubiquitin–proteasome machinery. Their mechanism of action raises exciting challenges,
Noé Herbel, Sophie Postel‐Vinay
wiley +1 more source
Improvement on corrosion resistance and biocompability of ZK60 magnesium alloy by carboxyl ion implantation [PDF]
arXiv, 2019 Magnesium alloys have been considered to be potential biocompatible metallic materials. Further improvement on the anti-corrosion is expected to make this type of materials more suitable for biomedical applications in the fields of orthopedics, cardiovascular surgery and others.
arxiv
Interleukin 2 and stimulator lymphoblastoid cells will induce human thymocytes to bind and kill K562 targets. [PDF]
, 1982 Human thymocytes cultured in the presence of IL-2 and an irradiated B cell line became cytotoxic to K562 target cells. Thymocytes cultured alone or with only IL-2 exhibited almost no killing, but thymocytes cultured in the presence of stimulator cells ...
Golub, SH, Sidell, N, Torten, M
core