Results 191 to 200 of about 441,917 (361)

Ofatumumab treatment in new‐onset narcolepsy type 1 following SARS‐CoV‐2 infection

open access: yesAnnals of Clinical and Translational Neurology, Volume 12, Issue 3, Page 666-669, March 2025.
Abstract Objectives To explore the efficacy of ofatumumab in new onset narcolepsy type 1 following SARS‐CoV‐2 infection. Methods We present a 9‐year‐old girl who experienced new onset narcolepsy type 1 following SARS‐CoV‐2 infection. Polysomnography (PSG) followed by a daytime multiple sleep latency test (MSLT) was under taken after admission. A lumbar
Xiaoli Wang   +3 more
wiley   +1 more source

Epigenome‐wide association study, meta‐analysis, and multiscore profiling of whole blood in Parkinson's disease

open access: yesAnnals of Clinical and Translational Neurology, Volume 12, Issue 4, Page 701-713, April 2025.
Abstract Objectives An increasing body of evidence indicates altered DNA methylation in Parkinson's disease, yet the reproducibility and utility of such methylation changes are largely unexplored. We aimed to further elucidate the role of dysregulated DNA methylation in Parkinson's disease and to evaluate the biomarker potential of methylation‐based ...
Ingeborg Haugesag Lie   +4 more
wiley   +1 more source

Cytoxicity of root canal antiseptics used in dental practice on L929 fibroblasts: calcium hydroxide powder vs. 2% chlorhexidine solution

open access: yesNovelty in Biomedicine, 2014
Background & Objective: Chlorhexidine solution is one of the widely used mouth antiseptic liquid that prevents teeth tissue damage and also has application as a root canal antiseptic.
Sahar Yaghmaei   +5 more
doaj  

CSF cytokine, chemokine and injury biomarker profile of glial fibrillary acidic protein (GFAP) autoimmunity

open access: yesAnnals of Clinical and Translational Neurology, Volume 12, Issue 4, Page 855-860, April 2025.
Abstract Defining the CSF cytokine/chemokine and injury biomarker signature of glial fibrillary acidic protein (GFAP) autoimmunity can inform immunopathogenesis. CSF GFAP‐IgG‐positive samples (N = 98) were tested for 17 cytokines/chemokines, neurofilament light chain (NfL), and GFAP (ELLA, Bio‐Techne).
Yahel Segal   +11 more
wiley   +1 more source

Testing genotoxicity and cytotoxicity strategies for the evaluation of commercial radiosterilized fetal calf sera [PDF]

open access: green, 2009
Juan Pablo Pilili   +5 more
openalex   +1 more source

Histone Deacetylase 6 Brain PET in Amyotrophic Lateral Sclerosis‐Frontotemporal Spectrum Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective [18F]EKZ‐001 is a positron emission tomography (PET) tracer targeting histone deacetylase 6 (HDAC6), an enzyme responsible for intracellular transport and clearance of misfolded proteins. HDAC6 modulation is a promising treatment strategy in neurodegenerative disorders, including amyotrophic lateral sclerosis (ALS).
Greet Vanderlinden   +15 more
wiley   +1 more source

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