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Unreliability of cytotoxic food testing.
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Cytotoxicity test and mass spectrometry of IPMC
Electronics and Communications in Japan, 2008AbstractIonic polymer‐metal composites (IPMC) are promising materials in biomedical actuators and sensors, as they are soft and flexible, thus assuring the safety of the device itself. The purpose of this study is to investigate the biocompatibility of IPMC in in vitro experiments in order to evaluate their applicability in biomedical fields.
Kazuto Takashima +4 more
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Toxicological testing of cytotoxic drugs (Review)
International Journal of Oncology, 2001Cytotoxic drugs are a unique therapeutic class of fundamental importance in current antineoplastic chemotherapy. These drugs belong to many chemical and chemotherapeutic classes. They are cytotoxic by design and are able to cause serious dose-limiting adverse effects at therapeutic doses.
P, Colombo +3 more
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Clonogenic cytotoxicity testing by microdrop encapsulation
Nature, 1993Cytotoxicity is defined as the in situ measurement of cellular function in response to a toxic substance. Cytotoxicity assays are widely used in drug screening and development research to minimize the number of compounds on which expensive mammalian animal model toxicology studies are performed.
B, Goguen, N, Kedersha
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The Cytotoxic Test for Leucocyte Antibodies
Vox Sanguinis, 1965RésuméLes auteurs décrivent une technique pour déterminer les iso‐anticorps cytotoxiques contre les leucocytes humains et présentent une critique concernant les facteurs variables qui peuvent intervenir dans les tests. Ces tests ne requièrent pas d'équipement ou d'habileté spéciale; ils sont rapides à pratiquer et donnent des résultats étonamment ...
C P, Engelfriet, A, Britten
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An approach to avoiding errors in cytotoxic testing
Journal of Immunological Methods, 1973Abstract It is shown that time and temperature influence the results of cytotoxic assays considerably. In order to avoid errors depending upon these factors a simple modification in counting the cells is recommended.
H, Zimpel, R, Stark, H G, Thiele
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