Results 41 to 50 of about 13,799,457 (333)
FoxO1 signaling in B cell malignancies and its therapeutic targeting
FoxO1 has context‐specific tumor suppressor or oncogenic character in myeloid and B cell malignancies. This includes tumor‐promoting properties such as stemness maintenance and DNA damage tolerance in acute leukemias, or regulation of cell proliferation and survival, or migration in mature B cell malignancies.
Krystof Hlavac+3 more
wiley +1 more source
Cytotoxicity of Reparative Endodontic Cements on Human Periodontal Ligament Stem Cells
Objective: To compare the cytotoxicity of commercial reparative endodontic cements on human periodontal ligament stem cells (hPDLSCs). Material and Methods: The culture of hPDLSCs was established.
Marlus da Silva Pedrosa+4 more
doaj
Cytotoxicity of polycarbonate orthodontic brackets
Aim: To assess the cytotoxicity of polycarbonate orthodontic brackets. Methods: Polycarbonate brackets from two different manufacturers, namely, Composite bracket (Morelli™) and Silkon Plus bracket (American Orthodontics™), were assessed.
Matheus Melo Pithon+6 more
doaj +1 more source
In Vitro Tests of FDM 3D-Printed Diclofenac Sodium-Containing Implants
One of the most promising emerging innovations in personalized medication is based on 3D printing technology. For use as authorized medications, 3D-printed products require different in vitro tests, including dissolution and biocompatibility ...
Petra Arany+16 more
doaj +1 more source
Evaluation of Toxicological Risks of Nail Coatings Containing Acrylate Monomer HEMA
Individuals working in nail salons are exposed to 2-hydroxyethyl methacrylate (HEMA). HEMA has been found to have several effects on the skin: skin itching, peeling, redness and allergic contact dermatitis.
Zane GRIGALE-SOROCINA+3 more
doaj +1 more source
Making tau amyloid models in vitro: a crucial and underestimated challenge
This review highlights the challenges of producing in vitro amyloid assemblies of the tau protein. We review how accurately the existing protocols mimic tau deposits found in the brain of patients affected with tauopathies. We discuss the important properties that should be considered when forming amyloids and the benchmarks that should be used to ...
Julien Broc, Clara Piersson, Yann Fichou
wiley +1 more source
Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley +1 more source
Autophagy in cancer and protein conformational disorders
Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
Avaliação da biocompatibilidade de vidro e vitrocerâmica do sistema SNCP (SiO2-Na2O-CaO-P2O5)
This article reports research results related to bioactivity and cytotoxicity tests using neutral red uptake method for glass powders and bulk glass ceramics belonging to the SNCP (SiO2-Na2O-CaO-P2O5) system.
Karoline Bastos Mundstock+3 more
doaj +1 more source
Background. Root canal obturation is performed by gutta-percha cones and sealer. Therefore, these materials, specially sealers, must be biocompatible.
Mohammad Shokrzadeh+4 more
doaj +1 more source