Cytotoxic and Mutagenic Effects and cell Viability of Polybia sericea Social Wasp Venom (Hymenoptera: Vespidae) [PDF]
The venom of social wasps can be a natural promising product for the development of drugs, since in recent decades studies have investigated its antimicrobial potential, anti-inflammatory, antioxidant, anticarcinogenic, among others for its future ...
Antonialli-Junior, William Fernando+8 more
core +2 more sources
Seamless Iterative Semi-Supervised Correction of Imperfect Labels in Microscopy Images [PDF]
In-vitro tests are an alternative to animal testing for the toxicity of medical devices. Detecting cells as a first step, a cell expert evaluates the growth of cells according to cytotoxicity grade under the microscope. Thus, human fatigue plays a role in error making, making the use of deep learning appealing.
arxiv
Changes of cytotoxicity of Ti-6Al-4V alloy made by DMLS technology as effect of the shot peening
Objective The aim the study was to investigate the impact of the shot peening process on the condition of the surface layer and biological properties of titanium alloy produced by means of the Direct Metal Laser Sintering (DMLS) method.
Remigiusz Żebrowski+3 more
doaj +1 more source
Mathematical analysis and simulation study of a phase-field model of prostate cancer growth with chemotherapy and antiangiogenic therapy effects [PDF]
Cytotoxic chemotherapy is a common treatment for advanced prostate cancer. These tumors are also known to rely on angiogenesis, i.e., the growth of local microvasculature via chemical signaling produced by the tumor. Thus, several clinical studies have been investigating antiangiogenic therapy for advanced prostate cancer, either as monotherapy or ...
arxiv
Background and aims. The aim of this study was to evaluate the effect of dilution and curing methods of an etch-and-rinse adhesive and a self-etching primer from the same manufacturer at early exposure time on cytotoxicity of primary hu-man gingival ...
Sepideh Banava+5 more
doaj +1 more source
Gap Junctions: The Claymore for Cancerous Cells [PDF]
Introduction: Gap junctions play an important role in the cell proliferation in mammalian cells as well as carcinogenesis. However, there are controversial issues about their role in cancer pathogenesis. This study was designed to evaluate genotoxicity and cytotoxicity of Carbenoxolone (CBX) as a prototype of inter-cellular gap junction blocker in MCF7
arxiv
Cytoxicity and cytostatic drug removal in a membrane bioreactor from wastewater [PDF]
The growing use of antineoplastic drugs in cancer therapy is an emerging issue in environmental research. The presence of the anticancer drug cyclophosphamide (CP) in municipal wastewater raises several environmental problems.
Albasi, Claire+5 more
core
Chloroquine-enhanced gene delivery mediated by carbon nanotubes [PDF]
Polyethyleneimine-coated double-walled carbon nanotubes (DWCNTs) were used for dual gene and drug delivery, after loading the DWCNTs with the drug chloroquine, a lysosomotropic compound that is able to promote escape from the lysosomal compartment ...
Borowiak-Palen+44 more
core +2 more sources
Comparison of 20nm silver nanoparticles synthesized with and without a gold core: Structure, dissolution in cell culture media, and biological impact on macrophages [PDF]
Widespread use of silver nanoparticles raises questions of environmental and biological impact. Many synthesis approaches are used to produce pure silver and silver-shell gold-core particles optimized for specific applications.
Baer, DR+10 more
core +1 more source
Computational Inference Methods for HIV-1 Selective Sweeps Shaped by Early Cytotoxic T-Lymphocyte Response [PDF]
In this work we develop a stochastic model of acute HIV infection, based on the well-known standard model, that allows us to simulate the complex mutation pathways of HIV escape from multiple CTL responses. Under this model, we describe two computational inference methods. In one, we use a Bayesian approach to construct posteriors for the parameters of
arxiv