Results 81 to 90 of about 281,175 (307)

Changes of cytotoxicity of Ti-6Al-4V alloy made by DMLS technology as effect of the shot peening

Annals of Agricultural and Environmental Medicine, 2020
Objective The aim the study was to investigate the impact of the shot peening process on the condition of the surface layer and biological properties of titanium alloy produced by means of the Direct Metal Laser Sintering (DMLS) method.
Remigiusz Żebrowski, Mariusz Walczak, Kazimierz Drozd, Mirosław Jerzy Jarosz   +3 more
doaj   +1 more source

Improved cytotoxicity testing of magnesium materials [PDF]

Materials Science and Engineering: B, 2011
Abstract Metallic magnesium (Mg) and its alloys are highly suitable for medical applications as biocompatible and biodegradable implant materials. Magnesium has mechanical properties similar to bone, stimulates bone regeneration, is an essential non-toxic element for the human body and degrades completely within the body environment.
Fischer, J., Proefrock, D., Hort, N., Willumeit, R., Feyerabend, F.   +4 more
openaire   +2 more sources

Use of graphene as protection film in biological environments [PDF]

, 2014
Corrosion of metal in biomedical devices could cause serious health problems to patients. Currently ceramics coating materials used in metal implants can reduce corrosion to some extent with limitations.
Chen, Yong P., Chung, Ting Fung, Crist, Scott A., Lee, Kyunghoon, Lee, Seunghyun, Lee, Sudarat, McNear, Kelly L., Ratliff, Timothy L., Yang, Chen, Zhang, Weixia, Zhong, Zhaohui   +10 more
core   +2 more sources

Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition

Molecular Oncology, EarlyView.
We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li, Shuichi Tatarano, Hirofumi Yoshino, Saeki Saito, Mitsuhiko Tominaga, Junya Arima, Ikumi Fukuda, Takashi Sakaguchi, Ryosuke Matsushita, Yasutoshi Yamada, Hideki Enokida   +10 more
wiley   +1 more source

Cytotoxicity tests for nanostructured chitosan/PEO membranes using the agar diffusion method

Materials Research, 2012
Electrospinning is used to produce fibers in the nanometer range by stretching a polymeric jet using electric fields of high magnitude. Chitosan is an abundant natural polymer that can be used to obtain biocompatible nanostructured membranes.
Valcinir Aloisio Scalla Vulcani, Maria Trindade Marques Bizarria, Marcos Akira d’Ávila, Lucia Helena Innocentini Mei, Cláudia Bernal, Janice Rodrigues Perussi   +5 more
doaj  

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

Molecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung, David Bickel, Lena C. M. Krause, Daria Ezeriņa, Christian Ickes, Julian Wojtachnia, Christine S. Gibhardt, Magdalena Shumanska, Khadija Wahni, Andrea Paluschkiwitz, Julia Malo Pueyo, Ekaterina Baranova, Wim Vranken, Hedwig Stanisz, Ioana Stejerean‐Todoran, Michael P. Schön, Joris Messens, Ivan Bogeski   +17 more
wiley   +1 more source

Impact of Dilution and Polymerization on Cytotoxicity of Dentin Adhesives to Human Gingival Fibroblasts: Early Exposure Time

Journal of Dental Research, Dental Clinics, Dental Prospects, 2015
Background and aims. The aim of this study was to evaluate the effect of dilution and curing methods of an etch-and-rinse adhesive and a self-etching primer from the same manufacturer at early exposure time on cytotoxicity of primary hu-man gingival ...
Sepideh Banava, Kaveh Najibfard, Franklin Garcia-Godoy, Mohammad Ali Saghiri, Mohammad Hossein Ghahremani, Naser Ostad   +5 more
doaj   +1 more source

Graphene nanoplatelets-reinforced magnesium metal matrix nanocomposites with superior mechanical and corrosion performance for biomedical applications

Journal of Magnesium and Alloys, 2020
Magnesium (Mg) metal matrix composites (MMCs) reinforced with graphene nanoplatelets (GNPs) have been developed by powder metallurgy (PM). GNPs with different concentrations (0.1, 0.2, and 0.3 wt.%), layer thicknesses (5 nm and 9 nm), and particle sizes (
Khurram Munir, Cuie Wen, Yuncang Li
doaj   +1 more source

Identification of the catalytic motif of the microbial ribosome inactivating cytotoxin colicin E3 [PDF]

, 2004
Colicin E3 is a cytotoxic ribonuclease that specifically cleaves 16S rRNA at the ribosomal A-site to abolish protein synthesis in sensitive Escherichia coli cells.
Bohm, Boon, Bowman, Carr, Cuchillo, Garinot-Schneider, Irie, Kerr, Kleanthous, Kleanthous, Makarov, Mosbahi, Ogawa, Ohno, Ohno, Ohno-Iwashita, Parret, Pommer, Rojas, Scholz, Schultz, Sidikaro, Smarda, Soelaiman, Steege, Tomita, Walker, Walker, Walker, Walker, Wallis   +30 more
core   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source