Results 81 to 90 of about 14,563,409 (378)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

The Diagnostic Efficacy of Age-Adjusted D-Dimer Cutoff Value and Pretest Probability Scores for Deep Venous Thrombosis

open access: yesClinical and Applied Thrombosis/Hemostasis, 2019
This study seeks to evaluate the diagnostic value of D-Dimer Plus and Innovance D-Dimer as well as the age-adjusted cutoff value for D-dimer detection in combination with 4 pretest probability (PTP) scores for deep venous thrombosis (DVT). A total of 688
Junxun Li MM, MHA   +5 more
doaj   +1 more source

D-Dimer Combined with Fibrinogen Predicts the Risk of Venous Thrombosis in Fracture Patients

open access: yesEmergency Medicine International, 2020
Objective. While D-dimer can successfully diagnose venous thrombosis due to its excellent negative predictive value (NPV), it cannot be used to detect venous thromboembolism (VTE) because of its low positive predictive value (PPV).
Chaohui Lin   +5 more
doaj   +1 more source

Elevated plasma D-dimer levels correlate with long term survival of gastric cancer patients. [PDF]

open access: yesPLoS ONE, 2014
BACKGROUND: Increasing evidence indicated plasma D-dimer could be regarded as a marker in cancers, however, its role in gastric cancer is still largely unknown.
Long Liu   +8 more
doaj   +1 more source

Standardizing the d-dimer Assay: Proposing the d-dimer International Managed Ratio [PDF]

open access: yesClinical Chemistry, 2015
To the Editor: The d-dimer assay currently lacks standardization, since each manufacturer uses a different cutoff to define an abnormal value. The existence of at least 6 commonly used assays—all with differing units and cutoffs—leads to confusion among practitioners.
Zachary P, Kahler, Jeffrey A, Kline
openaire   +2 more sources

D‐dimer Triage for COVID‐19 [PDF]

open access: yesAcademic Emergency Medicine, 2020
Coagulopathy and elevated D-dimer levels were recognized as prognostic factors early in Wuhan, China as accompanying more severe COVID-19 patient cases. We sought to determine the accuracy of normal vs elevated D-dimer blood levels at presentation, day 1, and on day 3 for predicting 28-day survival in a large cohort of consecutive PCR-proven COVID-19 ...
Li, Chenghong   +7 more
openaire   +2 more sources

Factors Associated With Positive D-dimer Results in Patients Evaluated for Pulmonary Embolism [PDF]

open access: yes, 2010
Objectives:  Available D-dimer assays have low specificity and may increase radiographic testing for pulmonary embolism (PE). To help clinicians better target testing, this study sought to quantify the effect of risk factors for a positive quantitative D-
Ansari   +23 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

The prognostic value of admission D-dimer level in patients with cardiogenic shock after acute myocardial infarction

open access: yesFrontiers in Cardiovascular Medicine, 2023
BackgroundShock is associated with the activation of the coagulation and fibrinolytic system, and D-dimer is the degradation product of cross-linked fibrin.
Yi Jiang   +8 more
doaj   +1 more source

HIV infection is associated with elevated biomarkers of immune activation in Ugandan adults with pneumonia. [PDF]

open access: yes, 2019
IntroductionPneumonia is an important cause of morbidity and mortality in persons living with human immunodeficiency virus (HIV) infection. How immune activation differs among HIV-infected and HIV-uninfected adults with pneumonia is unknown.MethodsThe ...
Byanyima, Patrick   +16 more
core   +2 more sources

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