Results 41 to 50 of about 13,846,557 (251)

Cloning of the D-lactate dehydrogenase gene from Lactobacillus delbrueckii subsp. bulgaricus by complementation in Escherichia coli. [PDF]

, 1991
A strain of Escherichia coli (FMJ144) deficient for pyruvate formate lyase and lactate dehydrogenase (LDH) was complemented with a genomic DNA library from Lactobacillus delbrueckii subsp. bulgaricus.
Ferain, Thierry, Ferain, T., Garmyn, Dominique, Pascal Hols, Hols, Pascal, Jean Delcour, Bernard, N., Delcour, Jean, Nathalie Bernard, Bernard, Nathalie, Thierry Ferain, Garmyn, D., Dominique Garmyn   +12 more
core   +1 more source

Unraveling the epigenetic code in cancer cell–tumor microenvironment crosstalk

Molecular Oncology, EarlyView.
Epigenetic regulation is a key driver of cancer development and progression. Diverse epigenetic alterations in cancer cells and components of the tumor microenvironment (TME) orchestrate their communication through multiple mechanisms. We discuss how the epigenetic code coordinates bidirectional cancer cell–TME crosstalk to promote cancer progression ...
Ji Hoon Park, Mi‐Young Kim
wiley   +1 more source

Induction of alcohol dehydrogenase and lactate dehydrogenase in hypoxically induced barley

, 1989
In barley (Hordeum vulgare L.), alcohol dehydrogenase (ADH) and lactate dehydrogenase (LDH) are induced by anaerobiosis in both aleurone layers and roots.
Good, A. G., Crosby, W. L.
core   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Production of d-lactate from glucose using Klebsiella pneumoniae mutants

Microbial Cell Factories, 2017
Background d-Lactate is a valued chemical which can be produced by some bacteria including Klebsiella pneumoniae. However, only a few studies have focused on K.
Xinjun Feng, Liqun Jiang, Xiaojuan Han, Xiutao Liu, Zhiqiang Zhao, Huizhou Liu, Mo Xian, Guang Zhao   +7 more
doaj   +1 more source

Using Unnatural Protein Fusions to Engineer a Coenzyme Self-Sufficiency System for D-Phenyllactic Acid Biosynthesis in Escherichia coli

Frontiers in Bioengineering and Biotechnology, 2021
The biosynthetic production of D-penyllactic acid (D-PLA) is often affected by insufficient supply and regeneration of cofactors, leading to high production cost, and difficulty in industrialization.
Zhao Qin, Dan Wang, Ruoshi Luo, Tinglan Li, Xiaochao Xiong, Peng Chen   +5 more
doaj   +1 more source

Evolution of D-lactate dehydrogenase activity from glycerol dehydrogenase and its utility for D-lactate production from lignocellulose

, 2011
Lactic acid, an attractive, renewable chemical for production of biobased plastics (polylactic acid, PLA), is currently commercially produced from food-based sources of sugar.
K. T. Shanmugam, Lonnie O. Ingram, Qingzhao Wang   +2 more
core   +1 more source

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Serum markers as an aid in the diagnosis of pulmonary fungal infections in AIDS patients

Brazilian Journal of Infectious Diseases, 2017
Introduction: The etiology of pulmonary infections in HIV patients is determined by several variables including geographic region and availability of antiretroviral therapy.
Ana Isabela Morsch Passos, Rachel Polo Dertkigil, Marcelo de Carvalho Ramos, Ariane Fidelis Busso-Lopes, Cibele Tararan, Erivan Olinda Ribeiro, Angélica Zaninelli Schreiber, Plinio Trabasso, Mariangela Ribeiro Resende, Maria Luiza Moretti   +9 more
doaj   +1 more source

D-Lactate dehydrogenase as a marker gene allows positive selection of transgenic plants [PDF]

, 2011
d-Lactate negatively affects Arabidopsis thaliana seedling development in a concentration-dependent manner. At media d-lactate concentrations greater than 5-10 mM the development of wild-type plants is arrested shortly after germination whereas plants ...
Veronica G. Maurino, Flügge, Ulf-Ingo, Engqvist, Martin,, Maurino, Veronica G., Wienstroer, J.,, Engqvist, Martin K.M., Kunz, H.H., Fl\ufcgge, U.I., Flügge, U.I.,, Maurino, V.G.,, Ulf-Ingo Flügge, Engqvist, Martin, Wienstroer, Judith, Judith Wienstroer, Flügge, U.I., Martin K.M. Engqvist, Kunz, H.H.,, Maurino, V.G., Hans-Henning Kunz, Wienstroer, J., Kunz, Hans-Henning, Maurino, Veronica G, Engqvist, Martin K.M   +22 more
core   +1 more source