Results 101 to 110 of about 722,974 (305)
A noninvasive molecular approach: exploiting species-locus-specific PCR primers in defeating numts and DNA cross-contamination of cercopithecidae [PDF]
, 2017 The lack of a standardized, noninvasive molecular approach to studying genetic aspects of primates has made it hard for primatologists to decode the evolutionary history of these species.
Abu Bakar, Muhammad Abdul Latiff +3 more
core
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Development of A PCR - Cycle Sequencing System for Animal Mitochondrial DNA Analysis [PDF]
, 1994 A system for the study of sequence polymorphisms in animal mitochondrial DNA was developed. This system consists of two candidate markers which are mitochondrial cytochrome b and D-loop.
Lau, Chin Hoon
core
FEBS Letters, EarlyView.This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel +13 more
wiley +1 more source
Proceedings of the Mongolian Academy of SciencesOur aim was to identify nucleotide polymorphisms, assess their distribution in haplotype diversity, and construct a phylogenetic tree by analyzing mtDNA markers of the Mongolian Tree Pipits(Anthus trivialis).
Ulziisaikhan Tumendemberel +3 more
doaj +1 more source
Growing transverse oscillations of a multistranded loop observed by SDO/AIA
, 2012 The first evidence of transverse oscillations of a multistranded loop with growing amplitudes and internal coupling observed by the Atomspheric Imaging Assembly (AIA) onboard the Solar Dynamics Observatory (SDO) is presented.
Aschwanden +17 more
core +1 more source
PALB2 self-interaction controls homologous recombination. [PDF]
, 2012 PALB2 is essential for BRCA2 anchorage to nuclear structures and for homologous recombinational repair of DNA double-strand breaks. Here, we report that the N-terminal coiled-coil motif of PALB2 regulates its self-association and homologous recombination.
Buisson, Rémi, Masson, Jean-Yves
core +1 more source
Diversity and complexity in neural organoids
FEBS Letters, EarlyView.Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley +1 more source
Mitochondrial Copy Number and D-Loop Variants in Pompe Patients.
Cell journal, 2016 Pompe disease is a rare neuromuscular genetic disorder and is classified into two forms of early and late-onset. Over the past two decades, mitochondrial abnor- malities have been recognized as an important contributor to an array of neuromuscular diseases.
Bahreini, Fatemeh +6 more
openaire +3 more sources
Genomes, expression profiles, and diversity of mitochondria of the White-footed Deermouse Peromyscus leucopus, reservoir of Lyme disease and other zoonoses. [PDF]
, 2019 The cricetine rodents Peromyscus leucopus and P. maniculatus are key reservoirs for several zoonotic diseases in North America. We determined the complete circular mitochondrial genome sequences of representatives of 3 different stock colonies of P ...
Baldwin-Brown, James +5 more
core +1 more source