Results 101 to 110 of about 18,707,175 (333)
A shift in the optimum pH of phospholipase D produced by activating long-chain anions [PDF]
, 1969 Richard H. Quarles, R. M. C. Dawson
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Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer
Molecular Oncology, EarlyView.This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu +7 more
wiley +1 more source
Collaborative Design of Controlled Experiments in the Presence of Subject Covariates [PDF]
arXivWe consider the optimal experimental design problem of allocating subjects to treatment or control when subjects participate in multiple, separate controlled experiments within a short time-frame and subject covariate information is available. Here, in addition to subject covariates, we consider the dependence among the responses coming from the ...
arxiv
D-Optimal designs for a multivariate regression model
Journal of Multivariate Analysis, 1992 AbstractConsidered is a linear regression model with a one-dimensional control variable and an m-dimensional response variable y. The components of y may be correlated with known covariance matrix. Let B be the covariance matrix of the Gauss-Markoff estimator for the unknown parameter vector of the model.
Olaf Krafft, Martin Schaefer
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Molecular Oncology, EarlyView.Triacsin C inhibition of the acyl‐CoA synthetase long chain (ACSL) family decreases multiple myeloma cell survival, proliferation, mitochondrial respiration, and membrane potential. Made with Biorender.com. Multiple myeloma (MM) is an incurable cancer of plasma cells with a 5‐year survival rate of 59%.
Connor S. Murphy +12 more
wiley +1 more source
Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer
Molecular Oncology, EarlyView.mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia +17 more
wiley +1 more source
Optimal digitization of 2-d images [PDF]
, 1984 Lars Nielsen, Kalle Åström, E.I. Jury
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Molecular Oncology, EarlyView.Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley +1 more source
Correction to “Optimal Urban Water Distribution Design” by D. R. Morgan and I. C. Goulter [PDF]
, 1985 D. R. Morgan, I. C. Goulter
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Optimal BIBD-extended designs [PDF]
arXiv, 2019 Balanced incomplete block designs (BIBDs) are a class of designs with v treatments and b blocks of size k that are optimal with regards to a wide range of optimality criteria, but it is not clear which designs to choose for combinations of v, b and k when BIBDs do not exist.
arxiv