Results 61 to 70 of about 24,603 (322)

Prolonged Corrected QT Interval as an Early Electrocardiographic Marker of Cyclophosphamide‐Induced Cardiotoxicity in Pediatric Hematology and Oncology Patients

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Cyclophosphamide (CY) is associated with potentially fatal cardiotoxicity, yet no electrocardiographic indices have been established for early detection of CY‐induced cardiomyopathy. This study aimed to determine whether corrected QT interval (QTc) prolongation can predict early onset of CY‐related cardiac dysfunction in pediatric ...
Junpei Kawamura   +5 more
wiley   +1 more source

A Method for Augmenting Supersaturated Designs with Newly Added Factors

open access: yesMathematics, 2022
Follow-up experimental designs are popularly used in industry. In practice, some important factors may be neglected for various reasons in the first-stage experiment and they need to be added in the next stage.
Chun-Wei Zheng   +3 more
doaj   +1 more source

Predicting Chronicity in Children and Adolescents With Newly Diagnosed Immune Thrombocytopenia at the Timepoint of Diagnosis Using Machine Learning‐Based Approaches

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Objectives To identify predictors of chronic ITP (cITP) and to develop a model based on several machine learning (ML) methods to estimate the individual risk of chronicity at the timepoint of diagnosis. Methods We analyzed a longitudinal cohort of 944 children enrolled in the Intercontinental Cooperative immune thrombocytopenia (ITP) Study ...
Severin Kasser   +6 more
wiley   +1 more source

Differential-integral Euler–Lagrange equations [PDF]

open access: yesIranian Journal of Numerical Analysis and Optimization
We study the calculus of variations problem in the presence of a system of differential-integral (D-I) equations. In order to identify the necessary optimality conditions for this problem, we derive the so-called D-I Euler–Lagrange equations.
Mohammedd Shehata
doaj   +1 more source

Optimization Design of Step Stress Accelerated Degradation Test for Motorized Spindle Based on Ds-Optimality

open access: yesApplied Sciences, 2021
In the accelerated degradation test (ADT) of motorized spindles, it is necessary to apply a variety of stresses to simulate real working conditions. However, the traditional accelerated test scheme optimization method does not consider the weight of ...
Hongxun Zhao   +5 more
doaj   +1 more source

Bayesian sequential experimental design for binary response data with application to electromyographic experiments [PDF]

open access: yes, 2014
We develop a sequential Monte Carlo approach for Bayesian analysis of the experimental design for binary response data. Our work is motivated by surface electromyographic (SEMG) experiments, which can be used to provide information about the ...
Azadi, Nammam Ali   +3 more
core   +3 more sources

Improved Outcomes for Older Children, Adolescents, and Young Adults With Neuroblastoma in the Post‐Immunotherapy Era: An Updated Report From the International Neuroblastoma Risk Group

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background We describe clinical and biologic characteristics of neuroblastoma in older children, adolescents, and young adults (OCAYA); describe survival outcomes in the post‐immunotherapy era; and identify if there is an age cut‐off that best discriminates outcomes.
Rebecca J. Deyell   +14 more
wiley   +1 more source

Computing Optimal Designs of multiresponse Experiments reduces to Second-Order Cone Programming [PDF]

open access: yes, 2010
Elfving's Theorem is a major result in the theory of optimal experimental design, which gives a geometrical characterization of $c-$optimality. In this paper, we extend this theorem to the case of multiresponse experiments, and we show that when the ...
Sagnol, Guillaume
core   +1 more source

Patient‐Level Barriers and Facilitators to Inpatient Physical Therapy in Adolescents and Young Adults With a Hematological Malignancy: A Qualitative Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite their increased risk for functional impairment resulting from cancer and its treatments, few adolescents and young adults (AYAs) with a hematological malignancy receive the recommended or therapeutic dose of exercise per week during inpatient hospitalizations.
Jennifer A. Kelleher   +8 more
wiley   +1 more source

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