Results 41 to 50 of about 29,402,319 (134)

Computer-aided identification of Trypanosoma brucei uridine diphosphate galactose 4'-epimerase inhibitors : toward the development of novel therapies for African sleeping sickness [PDF]

, 2010
Trypanosoma brucei, the causative agent of human African trypanosomiasis, affects tens of thousands of sub-Saharan Africans. As current therapeutics are inadequate due to toxic side effects, drug resistance, and limited effectiveness, novel therapies are
Durrant, Jacob D., Ferguson, Michael A. J., McCammon, J. Andrew, Urbaniak, Michael D.   +3 more
core   +5 more sources

Immobilization of Clostridium cellulolyticum d‑Psicose 3‑Epimerase on Artificial Oil Bodies

, 2016
The rare sugar d-psicose possesses several fundamental biological functions. d-Psicose 3-epimerase from Clostridium cellulolyticum (CC-DPEase) has considerable potential for use in d-psicose production.
Yuanxia Sun (1778155), Rey-Ting Guo (449264), Jason T. C. Tzen (1778161), Chih-Wen Tseng (1778158), Je-Ruei Liu (619827), Chien-Yi Liao (1729888), Chi-Chung Peng (1778152)   +6 more
core   +1 more source

Toxicological Assessment of D‐Allulose From a Novel One‐Step Fermentation Process Using Genetically Modified Escherichia coli: A 90‐Day Dietary Toxicity Study in Rats

Journal of Toxicology, Volume 2026, Issue 1, 2026.
D‐Allulose is a rare monosaccharide structurally similar to D‐fructose, characterized by low caloric content and relatively high sweetness. This study aimed to conduct a 90‐day oral toxicity test to systemically evaluate the potential toxicological effects of D‐allulose produced via a novel one‐step fermentation process using genetically engineered ...
Zinan Li, Yanmin Nie, Hongju Du, Wenjing Zhang, Shan Zheng, Wenshu Cong, Ying Feng, Guojun Li, Haiming Jing, Junyu Ning, Shan Gao, Phuping sucharitakul   +11 more
wiley   +1 more source

Update: Enzymatische Synthese für industrielle Anwendungen

Angewandte Chemie, Volume 137, Issue 27, July 1, 2025.
Die Biokatalyse hat sich zu einer nachhaltigen und wettbewerbsfähigen Alternative zur herkömmlichen chemischen Synthese entwickelt und ermöglicht die enzymbasierte Herstellung nicht nur von chemischen Grundstoffen, sondern auch von (nicht natürlichen) Aminosäuren, (seltenen) Zuckern und synthetischen Nukleotiden.
Thomas Bayer, Shuke Wu, Radka Snajdrova, Kai Baldenius, Uwe T. Bornscheuer   +4 more
wiley   +1 more source

Purification and Characterization of D-psicose 3 Epimerase (DPEase) From Escherichia coli BL21 (DE3) pET21b dpe

Pakistan Journal of Biological Sciences, 2020
The DPEase enzyme from Agrobacterium tumefaciens is more efficient and has a high activity in D-fructose. The dpe gene has been successfully cloned to Escherichia coli BL21 (DE3) pET-21b dpe but the enzyme has not been purified and its character is unknown. The intent of this study was to purify and assign of DPEase enzyme by recombinant E.
Deby EdyLiani, Yurnaliza Yurnaliza, Budi Saksono   +2 more
openaire   +2 more sources

Update of the list of qualified presumption of safety (QPS) recommended microbiological agents intentionally added to food or feed as notified to EFSA 21: Suitability of taxonomic units notified to EFSA until September 2024

EFSA Journal, Volume 23, Issue 1, January 2025.
Abstract The qualified presumption of safety (QPS) process was developed to provide a safety assessment approach for microorganisms intended for use in food or feed chains. In the period covered by this Statement, no new information was found that would change the status of previously recommended QPS taxonomic units (TUs).
EFSA Panel on Biological Hazards (BIOHAZ), Ana Allende, Avelino Alvarez‐Ordóñez, Valeria Bortolaia, Sara Bover‐Cid, Alessandra De Cesare, Wietske Dohmen, Laurent Guillier, Liesbeth Jacxsens, Maarten Nauta, Lapo Mughini‐Gras, Jakob Ottoson, Luisa Peixe, Fernando Perez‐Rodriguez, Panagiotis Skandamis, Elisabetta Suffredini, Marianne Chemaly, Pier Sandro Cocconcelli, Pablo Salvador Fernández Escámez, Miguel Prieto Maradona, Amparo Querol, Lolke Sijtsma, Juan Evaristo Suarez, Ingvar Sundh, Angela Botteon, Baptista Carolina, Barizzone Fulvio, Sandra Correia, Lieve Herman   +28 more
wiley   +1 more source

Study on the fusion expression of L-rhamnose-isomerase and D-psicose-3-epimerase [PDF]

D-Allose, a rare cis-aldohexose with extensive physiological functions, has significant applications in food, healthcare, and pharmaceutical fields.
Li, Xiao
core   +1 more source

Sequential whole cell conversion process for production of D-psicose and D- mannitol from D-fructose [PDF]

, 2018
Rare sugars, which exist only limited quantities naturally, have received considerable attention because of its various specific nutritional and biological functions.
Kim, Jae-Eun, Jeong, Seong-Hee, Kim, Seon-Won, Park, Ji-Bin   +3 more
core   +1 more source

Enzymatic Conversion of D-Psicose From D-Glucose by the Co-Expression of D-Psicose 3-Epimerase and Glucose Isomerase

, 2020
Escherichia coli was genetically modified for the production of D-psicose. A modified plasmid containing an extra copy of gene expression elements, including Ribosomal Binding Site (RBS), T7 promoter, multiple restriction enzyme cloning site, was ...
Chen, Xiaoyan
core  

UDP-N-Acetylglucosamine 4-Epimerase Activity Indicates the Presence of N-Acetylgalactosamine in Exopolysaccharides of Streptococcus thermophilus Strains [PDF]

, 2001
The monomer composition of the exopolysaccharides (EPS) produced by Streptococcus thermophilus LY03 and S. thermophilus Sfi20 were evaluated by high-pressure liquid chromatography with amperometric detection and nuclear magnetic resonance spectroscopy ...
Laws, Andrew P., Degeest, B., Vaningelgem, Frederik, De Vuyst, Luc   +3 more
core   +1 more source