Results 71 to 80 of about 39,485,272 (291)

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

Frequently Asked Questions Related to the Commission on Evidence-Based Policymaking's Report

open access: yes, 2017
List of frequently-asked questions regarding the final report of the U.S. Commission on Evidence-Based Policymaking with answers and clarifications. Questions are broken into five topics: general, National Secure Data Service (NSDS), privacy, access ...
United States. Commission on Evidence-Based Policymaking.
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Promise of Evidence-Based Policymaking, Final Report and Appendices A-D

open access: yes, 2017
Final report of the Commission on Evidence-Based Policymaking (CEP) describing their activities and findings regarding evidence access, privacy protections, accountability, and building capacity.
United States. Commission on Evidence-Based Policymaking
core  

Measurement of the mass difference m(D-s(+))-m(D+) at CDF II [PDF]

open access: yes, 2003
We present a measurement of the mass difference m(D-s(+))-m(D+), where both the D-s(+) and D+ are reconstructed in the phipi(+) decay channel. This measurement uses 11.6 pb(-1) of data collected by CDF II using the new displaced-track trigger.
Kroll, J   +999 more
core   +1 more source

Residual tail twisting in ascidian larvae is stabilized by asymmetric myofibrils that resist bilateral symmetry restoration

open access: yesFEBS Letters, EarlyView.
Ascidian Ciona larvae initially show strong clockwise tail twisting, which is largely corrected during development. However, a small residual twist remains. This study shows that organized helical myofibrils in tail muscles mechanically stabilize this residual asymmetry, preventing complete restoration of bilateral symmetry and revealing how embryos ...
Yuki S. Kogure   +3 more
wiley   +1 more source

Challenges to Bayesian Confirmation Theory [PDF]

open access: yes, 2011
While Bayesian analysis has enjoyed notable success with many particular problems of inductive inference, it is not the one true and universal logic of induction. I review why the Bayesian approach fails to provide this universal logic of induction. Some
Norton, JD   +2 more
core   +1 more source

Health diagnosis method of coal mine belt conveyor

open access: yesGong-kuang zidonghua, 2019
In view of problem of invalidation in dealing with conflicting evidence of D-S evidence theory used in health diagnosis method of coal mine belt conveyor based on multi-sensor information fusion, a health diagnosis method of coal mine belt conveyor based
QI Ruimin, WANG Xin
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

The Promise of Evidence-Based Policymaking: Report of the Commission on Evidence-Based Policymaking, Appendices E-H

open access: yes, 2017
Final report appendices E-H of the Commission on Evidence-Based Policymaking (CEP) containing the information gathered through the commission's survey of federal offices, public meeting materials and presentations, public input-hearing testimony and ...
United States. Commission on Evidence-Based Policymaking
core  

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