Results 81 to 90 of about 39,485,272 (291)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

The Promise of Evidence-Based Policymaking

open access: yes, 2017
Report of the Commission on Evidence-Based Policymaking providing a final report of their findings that..
United States. Commission on Evidence-Based Policymaking.
core  

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

open access: yesFEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa   +2 more
wiley   +1 more source

The Promise of Evidence-Based Policymaking: Appendices E-H

open access: yes, 2017
Supplementary appendices that support the final report of the Commission on Evidence-Based Policymaking including ..
United States. Commission on Evidence-Based Policymaking.
core  

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

Must Evidence Underdetermine Theory? [PDF]

open access: yes, 2003
According to the underdetermination thesis, all evidence necessarily underdetermines any scientific theory. Thus it is often argued that our agreement on the content of mature scientific theories must be due to social and other factors. Drawing on a long
Norton, John D., Norton, John D
core  

Gear Fault Diagnosis Method based on Multi-domain Feature and Improved D-S Evidence Theory

open access: yes, 2019
In order to fully and accurately identify the fault category of gear,a feature space model based on multi-domain characteristic parameters such as time domain,frequency domain and energy is established.
Fang Liu, Yanxue Wang
core   +1 more source

Bearing Fault Diagnosis using Multi-sensor Fusion based on weighted D-S Evidence Theory

open access: yes, 2018
This paper has presented a novel method for bearing fault diagnosis using a multi-sensor fusion approach based on an improved weighted Dempster-Shafer (D-S) evidence theory combined with Genetic Algorithm (GA).
Lin Shuiquan (17923016)   +4 more
core   +5 more sources

Trusted routing based on D-S evidence theory in wireless mesh network

open access: yesTongxin xuebao, 2011
Combined with Dempster-Shafer(D-S) evidence theory,a trust evaluation model was given,meanwhile,a trusted routing——T-AODV was also proposed which built trusted routings according to the trustworthiness of nodes calculated by the proposed trust evaluation
YANG Kai, MA Jian-feng, YANG Chao
doaj   +2 more sources

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

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