Results 11 to 20 of about 19,359 (212)

Age-Related Changes in Serum Lipid Levels, Hepatic Morphology, Antioxidant Status, Lipid Metabolism Related Gene Expression and Enzyme Activities of Domestic Pigeon Squabs (Columba livia)

Animals, 2020
The objective of this study was to evaluate the age-related changes in antioxidant status and the lipid metabolism of pigeon squabs (Columba livia), by determining the BW, antioxidant indices, serum lipid levels, lipid metabolism-related enzyme ...
Qianqian Xu, Huaiyu Li, Wenting Zhou, Xiaoting Zou, Xinyang Dong   +4 more
doaj   +1 more source

Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy

Hepatology, EarlyView., 2022
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann, Marti Cabanes‐Creus, Moritz Ertelt, Renina Gale Navarro, Julie Lucifora, Qinggong Yuan, Karin Nien‐Huber, Ahmed Abdelrahman, Xuan‐Khang Vu, Liang Zhang, Ann‐Christin Franke, Christian Schmithals, Albrecht Piiper, Annabelle Vogt, Maria Gonzalez‐Carmona, Jochen T. Frueh, Evelyn Ullrich, Philip Meuleman, Steven R. Talbot, Margarete Odenthal, Michael Ott, Erhard Seifried, Clara T. Schoeder, Joachim Schwäble, Leszek Lisowski, Hildegard Büning   +25 more
wiley   +1 more source

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

Hepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie, Jill E. Hunter, Amy Collins, Amelia Rushton, Lauren G. Russell, Erik Ramon‐Gil, Maja Laszczewska, Misti McCain, Marco Y. W. Zaki, Amber Knox, Yixin Seow, Laura Sabater, Daniel Geh, Neil D. Perkins, Helen L. Reeves, Dina Tiniakos, Derek A. Mann, Fiona Oakley   +17 more
wiley   +1 more source

Dissemination and Planned Demonstrator of New Precast Concrete Sandwich Panels

Proceedings, 2018
This paper presents work developing thin precast concrete sandwich panels for recladding and overcladding applications. These panels are designed for the retrofit of precast concrete structures where the underlying frame is structurally sound. Structural
Aidan Reilly, Richard O'Hegarty, Oliver Kinnane   +2 more
doaj   +1 more source

Hematopoietic Stem Cells Are Intrinsically Protected against MLL-ENL-Mediated Transformation

Cell Reports, 2014
Studies of developmental pathways of hematopoietic stem cells (HSCs) have defined lineage relationships throughout the blood system. This is relevant to acute myeloid leukemia (AML), where aggressiveness and therapeutic responsiveness can be influenced ...
Amol Ugale, Gudmundur L. Norddahl, Martin Wahlestedt, Petter Säwén, Pekka Jaako, Cornelis Jan Pronk, Shamit Soneji, Jörg Cammenga, David Bryder   +8 more
doaj   +1 more source

DWARF14, A Receptor Covalently Linked with the Active Form of Strigolactones, Undergoes Strigolactone-Dependent Degradation in Rice

Frontiers in Plant Science, 2017
Strigolactones (SLs) are the latest confirmed phytohormones that regulate shoot branching by inhibiting bud outgrowth in higher plants. Perception of SLs depends on a novel mechanism employing an enzyme-receptor DWARF14 (D14) that hydrolyzes SLs and ...
Qingliang Hu, Qingliang Hu, Yajun He, Yajun He, Lei Wang, Simiao Liu, Xiangbing Meng, Guifu Liu, Yanhui Jing, Mingjiang Chen, Xiaoguang Song, Liang Jiang, Hong Yu, Bing Wang, Jiayang Li, Jiayang Li   +15 more
doaj   +1 more source

TSH levels after fresh embryo transfer are associated with reproductive outcomes in euthyroid women undergoing the first IVF/ICSI cycles

Scientific Reports, 2023
To investigate whether there is a relationship between TSH levels on the 14th day post embryo transfer (D14 TSH levels) and the reproductive outcomes in euthyroid women who are free from levothyroxine (LT4) treatment and undergo the first in vitro ...
Yuchao Zhang, Yanli Liu, Wenbin Wu, Zhen Li, Bingnan Ren, Yichun Guan   +5 more
doaj   +1 more source

Impact of Covid-19 pandemic on household income: results of a survey of the economically active population

Studia Universitatis Vasile Goldis Arad, Seria Stiinte Economice, 2022
The aim of the study is to assess the current impact of the Covid-19 pandemic on the level of household income in modern national economies according to data for 2020.
Pinkovetskaia Iuliia
doaj   +1 more source

QUIMIOTERAPIA DE RESGATE EM PACIENTES COM D14 POSITIVO DE INDUÇÃO DE LEUCEMIA MIELOIDE AGUDA: ANÁLISE DE FATORES QUE PODEM INFLUENCIAR NA DE REMISSÃO COMPLETA

Hematology, Transfusion and Cell Therapy, 2023
Introdução/Objetivos: A avaliação de resposta na leucemia mieloide aguda (LMA) classicamente se dá ao final de 3-4 semanas após o início da quimioterapia, por volta do 28ºdia. Há muitos estudos que avaliam a quantidade de mieloblastos no 14ºdia (D14) com
IL Pontes, MS Cidrão, JBSC Cidrão, DS Oliveira, GM Oliveira, FET Filho, LFA Alves, FAC Silva, LA Gurgel, KMC Albuquerque   +9 more
doaj   +1 more source

Longitudinal assessment of dental erosion-abrasion by cross-polarization optical coherence tomography in vitro [PDF]

Brazilian Oral Research, 2023
: This study tested a novel in vitro dental erosion-abrasion model and the performance of cross-polarization optical coherence tomography (CP-OCT) in longitudinally monitoring the simulated lesions.
Maria Jacinta Rosario Romero, Sávio José Cardoso Bezerra, Daniel Fried, Frank Lippert, George Joseph Eckert, Anderson Takeo Hara   +5 more
doaj   +1 more source