Results 11 to 20 of about 84,651 (270)

Conformational Dynamics of the D53−D3−D14 Complex in Strigolactone Signaling

Plant and Cell Physiology, 2023
Strigolactones (SLs) play fundamental roles in regulating plant architecture, which is a major factor determining crop yield. The perception and signal transduction of SLs require the formation of a complex containing the receptor DWARF14 (D14), an F-box
Simiao Liu, Jia Wang, Bin Song, Xinqi Gong, Huihui Liu, Qingliang Hu, Junhui Zhang, Qianqian Li, Jie Zheng, Hongwei Wang, H. E. Xu, Jiayang Li, Bing Wang   +12 more
semanticscholar   +1 more source

Dwarf and High Tillering1 represses rice tillering through mediating the splicing of D14 pre-mRNA.

The Plant Cell, 2022
Strigolactones (SLs) constitute a class of plant hormones that regulate many aspects of plant development, including repressing tillering in rice (Oryza sativa). However, how SL pathways are regulated is still poorly understood.
Tianzhen Liu, Xin Zhang, Huan Zhang, Z. Cheng, Jun Liu, Chunlei Zhou, Sheng Luo, Weifeng Luo, Shuai Li, Xinxin Xing, Yanqi Chang, Cuilan Shi, Yulong Ren, Shanshan Zhu, C. Lei, Xiuping Guo, Jie Wang, Zhichao Zhao, Haiyang Wang, H. Zhai, Qibing Lin, J. Wan   +21 more
semanticscholar   +1 more source

A structural homologue of the plant receptor D14 mediates responses to strigolactones in the fungal phytopathogen Cryphonectria parasitica

New Phytologist, 2022
Summary Strigolactones (SLs) are plant hormones and important signalling molecules required to promote arbuscular mycorrhizal (AM) symbiosis. While in plants an α/β‐hydrolase, DWARF14 (D14), was shown to act as a receptor that binds and cleaves SLs, the ...
V. Fiorilli, M. Forgia, Alexandre de Saint Germain, Giulia D'Arrigo, David Cornu, Philippe Le Bris, S. Al‐Babili, F. Cardinale, C. Prandi, F. Spyrakis, F. Boyer, M. Turina, L. Lanfranco   +12 more
semanticscholar   +1 more source

Development, Characterization and Cell Viability Inhibition of PVA Spheres Loaded with Doxorubicin and 4′-Amino-1-Naphthyl-Chalcone (D14) for Osteosarcoma

Polymers, 2021
Chalcones (1,3-diaryl-2-propen-1-ones) are naturally occurring polyphenols with known anticancer activity against a variety of tumor cell lines, including osteosarcoma (OS). In this paper, we present the preparation and characterization of spheres (~2 mm)
Viviane Seba, G. G. de Lima, B. Pereira, Gabriel Silva, Luiza S. Reinhardt, P. Arantes, B. Chee, M. B. dos Santos, S. C. França, L. Regasini, A. Fachin, Z. Cao, M. Nugent, M. Marins   +13 more
semanticscholar   +1 more source

Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy

Hepatology, EarlyView., 2022
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann, Marti Cabanes‐Creus, Moritz Ertelt, Renina Gale Navarro, Julie Lucifora, Qinggong Yuan, Karin Nien‐Huber, Ahmed Abdelrahman, Xuan‐Khang Vu, Liang Zhang, Ann‐Christin Franke, Christian Schmithals, Albrecht Piiper, Annabelle Vogt, Maria Gonzalez‐Carmona, Jochen T. Frueh, Evelyn Ullrich, Philip Meuleman, Steven R. Talbot, Margarete Odenthal, Michael Ott, Erhard Seifried, Clara T. Schoeder, Joachim Schwäble, Leszek Lisowski, Hildegard Büning   +25 more
wiley   +1 more source

c‐Rel–dependent Chk2 signaling regulates the DNA damage response limiting hepatocarcinogenesis

Hepatology, EarlyView., 2022
In response to genotoxic injury, c‐Rel upregulates ATM‐Chk2‐p53 pathway DNA damage proteins to limiting hepatocarcinogenesis. Abstract Background and Aims Hepatocellular carcinoma (HCC) is a leading cause of cancer‐related death. The NF‐κB transcription factor family subunit c‐Rel is typically protumorigenic; however, it has recently been reported as a
Jack Leslie, Jill E. Hunter, Amy Collins, Amelia Rushton, Lauren G. Russell, Erik Ramon‐Gil, Maja Laszczewska, Misti McCain, Marco Y. W. Zaki, Amber Knox, Yixin Seow, Laura Sabater, Daniel Geh, Neil D. Perkins, Helen L. Reeves, Dina Tiniakos, Derek A. Mann, Fiona Oakley   +17 more
wiley   +1 more source

Early vessel destabilization mediated by Angiopoietin-2 and subsequent vessel maturation via Angiopoietin-1 induce functional neovasculature after ischemia. [PDF]

, 2013
We assessed whether Angiopoietin-2 (Ang2), a Tie2 ligand and partial antagonist of Angiopoietin-1 (Ang1), is required for early vessel destabilization during postischemic angiogenesis, when combined with vascular growth factors.
Chillo, Omary, Deindl, Elisabeth, Hinkel, Rabea, Kupatt, Christian, Lee, Seungmin, Qin, Di, Trenkwalder, Teresa   +6 more
core   +3 more sources

Language Modeling with Power Low Rank Ensembles [PDF]

, 2014
We present power low rank ensembles (PLRE), a flexible framework for n-gram language modeling where ensembles of low rank matrices and tensors are used to obtain smoothed probability estimates of words in context.
Dyer, Chris, Parikh, Ankur P., Saluja, Avneesh, Xing, Eric P.   +3 more
core   +2 more sources

Dissemination and Planned Demonstrator of New Precast Concrete Sandwich Panels

Proceedings, 2018
This paper presents work developing thin precast concrete sandwich panels for recladding and overcladding applications. These panels are designed for the retrofit of precast concrete structures where the underlying frame is structurally sound. Structural
Aidan Reilly, Richard O'Hegarty, Oliver Kinnane   +2 more
doaj   +1 more source

Impact of Covid-19 pandemic on household income: results of a survey of the economically active population

Studia Universitatis Vasile Goldis Arad, Seria Stiinte Economice, 2022
The aim of the study is to assess the current impact of the Covid-19 pandemic on the level of household income in modern national economies according to data for 2020.
Pinkovetskaia Iuliia
doaj   +1 more source