Results 21 to 30 of about 6,867,240 (296)
Regulation of Protein Kinase D1 Activity [PDF]
Molecular Pharmacology, 2012 Protein kinase D1 (PKD1) is a stress-activated serine/threonine kinase that plays a vital role in various physiologically important biological processes, including cell growth, apoptosis, adhesion, motility, and angiogenesis. Dysregulated PKD1 expression also contributes to the pathogenesis of certain cancers and cardiovascular disorders.
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Mechanisms of Regulation of Phospholipase D1 by Protein Kinase Cα [PDF]
Journal of Biological Chemistry, 2003 It has been suggested that protein-protein interaction is important for protein kinase C (PKC) alpha to activate phospholipase D1 (PLD1). To determine the one or more sites on PKCalpha that are involved in binding to PLD1, fragments containing the regulatory domain, catalytic domain, and C1-C3 domain of PKCalpha were constructed and shown to be ...
Hu, T. H., Exton, J. H.
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Frontiers in Plant Science, 2016 Melatonin is important in the protection of plants suffering various forms of abiotic stress. The molecular mechanisms underlying the melatonin-mediated protection of their photosynthetic machinery are not completely resolved. This study investigates the
Xiaoting Zhou +6 more
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Co-translational Assembly of the D1 Protein into Photosystem II [PDF]
Journal of Biological Chemistry, 1999 Assembly of multi-subunit membrane protein complexes is poorly understood. In this study, we present direct evidence that the D1 protein, a multiple membrane spanning protein, assembles co-translationally into the large membrane-bound complex, photosystem II.
L, Zhang +3 more
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Oligomycin induced the proteasomal degradation of cyclin D1 protein [PDF]
The Journal of Antibiotics, 2009 We searched for compounds that affect the cyclin D1/retinoblastoma protein pathway from the in-house natural product library using a recombinant adenovirus with the Cre/loxP-regulated cyclin D1 overexpression system, and we found that oligomycin inhibited cell growth more effectively in cyclin D1-overexpressing SW480 cells than in control SW480 cells ...
Mai, Kanai +4 more
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Quantitative phosphoproteomics of cytotoxic T cells to reveal Protein Kinase D 2 regulated networks [PDF]
, 2014 The focus of the present study was to characterize the phosphoproteome of cytotoxic T cells and to explore the role of the serine threonine kinase PKD2 (Protein Kinase D2) in the phosphorylation networks of this key lymphocyte population.
Goebel, Juergen +3 more
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PLoS ONE, 2016 D1 protein in the PSII reaction center is the major target of photodamage, and it exhibits the highest turnover rate among all the thylakoid proteins.
Fubiao Wang +8 more
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Regulation of Cardiac Stress Signaling by Protein Kinase D1 [PDF]
Molecular and Cellular Biology, 2006 In response to pathological stresses such as hypertension or myocardial infarction, the heart undergoes a remodeling process that is associated with myocyte hypertrophy, myocyte death, and fibrosis. Histone deacetylase 5 (HDAC5) is a transcriptional repressor of cardiac remodeling that is subject to phosphorylation-dependent neutralization in response ...
Brooke C, Harrison +10 more
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Reciprocal regulation of protein synthesis and carbon metabolism for thylakoid membrane biogenesis [PDF]
, 2013 Metabolic control of gene expression coordinates the levels of specific gene products to meet cellular demand for their activities. This control can be exerted by metabolites acting as regulatory signals and/or a class of metabolic enzymes with dual ...
Bohne, Alexandra-Viola +20 more
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Journal of Biological Chemistry, 2014 Background: Unicellular cyanobacteria separate photosynthesis and nitrogen fixation using a day-night cycle. Results: Cyanothece 51142 expresses a D1 protein exclusively in the dark period that assembles nonfunctional photosystem II.
Kimberly M. Wegener +2 more
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