Results 31 to 40 of about 6,867,240 (296)

Protein allostery. computational characterization of diguanylate cyclase PleD [PDF]

, 2009
In biology, accurate cellular regulation in response to environmental signals is crucial for the fitness of organisms. On the molecular level the modulation of protein activity is often achieved by the binding of a signaling molecule or by covalent ...
Schmid, Franziska F.-F.
core   +1 more source

Protein Kinase D1: A New Component in TLR9 Signaling [PDF]

The Journal of Immunology, 2008
AbstractProtein kinase D1 (PKD1) is expressed ubiquitously and regulates diverse cellular processes such as oxidative stress, gene expression, cell survival, and vesicle trafficking. However, the presence and function of PKD1 in monocytic cells are currently unknown.
Jeoung-Eun, Park, Young-In, Kim, Ae-Kyung, Yi   +2 more
openaire   +2 more sources

Cyclin D1 Protein Tissue Detection in Laryngeal Cancer

ORL, 2005
Cyclin D1 (CCND1) is a set of periodic regulatory proteins that is believed to govern cell cycle transit from G1 into S phase. Overexpression of CCND1 leads to abnormal cellular proliferation which underlies processes of tumorigenesis; CCND1 can thus function as a cooperative oncogene in cell transformation.
Segas, JV, Lazaris, AC, Nikolopoulos, TP, Kavantzas, NG, Lendari, IE, Tzagkaroulakis, AM, Patsouris, ES, Ferekidis, EA   +7 more
openaire   +3 more sources

Protein Kinase D1-Dependent Phosphorylation of Dopamine D1 Receptor Regulates Cocaine-Induced Behavioral Responses [PDF]

Neuropsychopharmacology, 2013
The dopamine (DA) D1 receptor (D1R) is critically involved in reward and drug addiction. Phosphorylation-mediated desensitization or internalization of D1R has been extensively investigated. However, the potential for upregulation of D1R function through phosphorylation remains to be determined.
Ning, Wang, Ping, Su, Ying, Zhang, Jie, Lu, Baoming, Xing, Kai, Kang, Wenqi, Li, Yun, Wang   +7 more
openaire   +2 more sources

Cytoplasmic N-Terminal Protein Acetylation Is Required for Efficient Photosynthesis in Arabidopsis [PDF]

, 2003
The Arabidopsis atmak3-1 mutant was identified on the basis of a decreased effective quantum yield of photosystem II. In atmak3-1, the synthesis of the plastome-encoded photosystem II core proteins D1 and CP47 is affected, resulting in a decrease in the ...
Masiero, S., Leister, D., Dietzmann, A., N. A. Gardner, Pesaresi, Paolo, Lutz Eichacker, Gardner, N., Dietzmann, Angela, Francesco Salamini, Salamini, Francesco, P. Pesaresi, Nora A. Gardner, Wickner, Reed B., Wickner, R., Salamini, F., Reed Wickner, Pesaresi, P., Leister, Dario, Gardner, Nora A., Masiero, Simona, Simona Masiero, Eichacker, L., Eichacker, Lutz A., D. Leister, Wickner, Reed, F. Salamini, Dario Leister, Paolo Pesaresi, R. Wickner, Gardner, N. A., L. Eichacker, Angela Dietzmann, A. Dietzmann, S. Masiero   +33 more
core   +1 more source

The role of dimerisation in the cellular trafficking of G-protein-coupled receptors [PDF]

, 2010
The concept that G-protein-coupled receptors can exist as homomeric and/or heteromeric complexes is now well established. Despite this, how dynamic such interactions are and if this may be modulated during receptor trafficking remain topics of debate ...
Milligan, Graeme
core   +1 more source

Mechanism of Persistent Protein Kinase D1 Translocation and Activation [PDF]

Developmental Cell, 2003
The specificity of many signal transduction pathways relies on the spatiotemporal features of each signaling step. G protein-coupled receptor-mediated activation of protein kinases leads to diverse cellular effects. Upon receptor activation, PKD1 and several C-type protein kinases (PKCs), translocate to the plasma membrane and become catalytically ...
Oancea, Elena, Bezzerides, Vassilios J., Greka, Anna, Clapham, David E.   +3 more
openaire   +2 more sources

HCF243 Encodes a Chloroplast-Localized Protein Involved in the D1 Protein Stability of the Arabidopsis Photosystem II Complex1[W][OA]

Plant Physiology, 2011
Numerous auxiliary nuclear factors have been identified to be involved in the dynamics of the photosystem II (PSII) complex. In this study, we characterized the high chlorophyll fluorescence243 (hcf243) mutant of Arabidopsis (Arabidopsis thaliana), which
Dongyuan Zhang, Gongke Zhou, Bingbing Liu, Y. Kong, N. Chen, Q. Qiu, H. Yin, Jiaxing An, Fang Zhang, Fan Chen   +9 more
semanticscholar   +1 more source

Requirement of protein kinase D1 for pathological cardiac remodeling [PDF]

Proceedings of the National Academy of Sciences, 2008
The adult heart responds to biomechanical stress and neurohormonal signaling by hypertrophic growth, accompanied by fibrosis, diminished pump function, and activation of a fetal gene program. Class II histone deacetylases (HDACs) suppress stress-dependent remodeling of the heart via their association with the MEF2 transcription factor, an ...
Jens, Fielitz, Mi-Sung, Kim, John M, Shelton, Xiaoxia, Qi, Joseph A, Hill, James A, Richardson, Rhonda, Bassel-Duby, Eric N, Olson   +7 more
openaire   +2 more sources

Construction of a Cyclin D1-Cdk2 Fusion Protein to Model the Biological Functions of Cyclin D1-Cdk2 Complexes [PDF]

Journal of Biological Chemistry, 2004
Cyclin D1 is frequently overexpressed in human breast cancers, and cyclin D1 overexpression correlates with poor prognosis. Cyclin D1-Cdk2 complexes were previously observed in human breast cancer cell lines, but their role in cell cycle regulation and transformation was not investigated.
Anna, Chytil, Mary, Waltner-Law, Robert, West, David, Friedman, Mary, Aakre, Dana, Barker, Brian, Law   +6 more
openaire   +2 more sources