Results 51 to 60 of about 3,451,797 (254)
Protein Kinase D1: A New Component in TLR9 Signaling [PDF]
The Journal of Immunology, 2008 AbstractProtein kinase D1 (PKD1) is expressed ubiquitously and regulates diverse cellular processes such as oxidative stress, gene expression, cell survival, and vesicle trafficking. However, the presence and function of PKD1 in monocytic cells are currently unknown.
Jeoung-Eun, Park +2 more
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Animal Nutrition, 2020 This experiment was conducted to investigate the effects of dietary lipid-to-carbohydrate ratio on growth and carbohydrate metabolism in juvenile cobia (Rachycentron canadum). Six isonitrogenous diets were prepared to vary in lipid-to-carbohydrate ratio (
Hongxia Zhao +5 more
doaj +1 more source
Construction of a Cyclin D1-Cdk2 Fusion Protein to Model the Biological Functions of Cyclin D1-Cdk2 Complexes [PDF]
Journal of Biological Chemistry, 2004 Cyclin D1 is frequently overexpressed in human breast cancers, and cyclin D1 overexpression correlates with poor prognosis. Cyclin D1-Cdk2 complexes were previously observed in human breast cancer cell lines, but their role in cell cycle regulation and transformation was not investigated.
Anna, Chytil +6 more
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Cytoplasmic N-Terminal Protein Acetylation Is Required for Efficient Photosynthesis in Arabidopsis [PDF]
, 2003 The Arabidopsis atmak3-1 mutant was identified on the basis of a decreased effective quantum yield of photosystem II. In atmak3-1, the synthesis of the plastome-encoded photosystem II core proteins D1 and CP47 is affected, resulting in a decrease in the ...
Masiero, S. +33 more
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Crop Journal, 2019 Retrotransposons account for a large proportion of the genome and genomic variation, and play key roles in creating novel genes and diversifying the genome in many eukaryotic species. Although retrotransposons are abundant in plants, their roles had been
Meicheng Zhao +4 more
doaj +1 more source
Requirement of protein kinase D1 for pathological cardiac remodeling [PDF]
Proceedings of the National Academy of Sciences, 2008 The adult heart responds to biomechanical stress and neurohormonal signaling by hypertrophic growth, accompanied by fibrosis, diminished pump function, and activation of a fetal gene program. Class II histone deacetylases (HDACs) suppress stress-dependent remodeling of the heart via their association with the MEF2 transcription ...
Jens, Fielitz +7 more
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Hsp90 Breaks the Deadlock of the Hsp70 Chaperone System [PDF]
, 2018 Protein folding in the cell requires ATP-driven chaperone machines such as the conserved Hsp70 and Hsp90. It is enigmatic how these machines fold proteins.
Mayer, Matthias +5 more
core +2 more sources
The promyelocytic leukemia (PML) protein suppresses cyclin D1 protein production by altering the nuclear cytoplasmic distribution of cyclin D1 mRNA [PDF]
Oncogene, 2000 The majority of the promyelocytic leukemia (PML) protein is present in nuclear bodies which are altered in several pathogenic conditions including acute promyelocytic leukemia. PML nuclear bodies are found in nearly all cells yet their function remains unknown.
H K, Lai, K L, Borden
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Protein allostery. computational characterization of diguanylate cyclase PleD [PDF]
, 2009 In biology, accurate cellular regulation in response to environmental signals is crucial for the fitness of organisms. On the molecular level the modulation of protein activity is often achieved by the binding of a signaling molecule or by covalent ...
Schmid, Franziska F.-F.
core +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source