Results 71 to 80 of about 10,757,883 (334)

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

open access: yesMolecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira   +7 more
wiley   +1 more source

SOX11 expression is highly specific for mantle cell lymphoma and identifies the cyclin D1-negative subtype

open access: yesHaematologica, 2009
Background Cyclin D1-negative mantle cell lymphoma is difficult to distinguish from other small B-cell lymphomas. The clinical and pathological characteristics of patients with this form of lymphoma have not been well defined.
Ana Mozos   +23 more
doaj   +1 more source

Mechanism of photoinhibition in vivo. A reversible light-induced conformational change of reaction center II is related to an irreversible modification of the D1 protein.

open access: yesJournal of Biological Chemistry, 1990
The light-induced inactivation of the photochemical reaction center II (RCII) of oxygenic chloroplasts (photoinhibition) was investigated in cells and isolated thylakoids of the green alga Chlamydomonas reinhardtii.
I. Ohad   +4 more
semanticscholar   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Glycogen synthase kinase 3 has a limited role in cell cycle regulation of cyclin D1 levels

open access: yesBMC Cell Biology, 2006
Background The expression level of cyclin D1 plays a vital role in the control of proliferation. This protein is reported to be degraded following phosphorylation by glycogen synthase kinase 3 (GSK3) on Thr-286. We recently showed that phosphorylation of
Hitomi Masahiro   +6 more
doaj   +1 more source

A novel metabolic form of the 32 kDa-D1 protein in the grana-localized reaction center of photosystem II.

open access: yesJournal of Biological Chemistry, 1990
Two forms of the 32 kDa-D1 reaction center protein of photosystem II (PSII), having slightly different mobilities on denaturing polyacrylamide gels, have been resolved in Spirodela oligorrhiza, Glycine max L., Gossypium hirsutum L., Triticum aestivum L.,
F. Callahan   +5 more
semanticscholar   +1 more source

PLD1 (phospholipase D1, phosphatidylcholine-specific) [PDF]

open access: yes, 2011
Review on PLD1 (phospholipase D1, phosphatidylcholine-specific), with data on DNA, on the protein encoded, and where the gene is ...
Lee, CS   +5 more
core   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Surface modification of 3D‐printed polycaprolactone scaffolds with silk fibroin for bone tissue engineering

open access: yesFEBS Open Bio, EarlyView.
Coating 3D‐printed PCL scaffolds with silk fibroin can improve biocompatibility and bone cell adhesion. One innovative design for tissue‐engineering scaffolds uses 3D printing technology. Here, we used polycaprolactone (PCL) filament as a biocompatible material to design a porous 3D scaffold for bone tissue engineering.
Hamed Koeini   +7 more
wiley   +1 more source

Characterization of tryptophan oxidation affecting D1 degradation by FtsH in the photosystem II quality control of chloroplasts

open access: yeseLife, 2023
Photosynthesis is one of the most important reactions for sustaining our environment. Photosystem II (PSII) is the initial site of photosynthetic electron transfer by water oxidation.
Yusuke Kato   +12 more
doaj   +1 more source

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