Results 81 to 90 of about 258,771 (261)

Multi‐Axis Stretchable Zippers for Personalized Wound Healing

Advanced Science, EarlyView.
Multi‐axis stretchable zippers can adapt to complex wound morphologies and enable personalized wound treatment through programmable contraction. This morphological matching strategy helps accelerate wound closure, improve blood perfusion, promote epithelial regeneration, and enhance collagen remodeling, pioneering new directions for personalized and ...
Siyuan Cai, Guang Yao, Zijian Chen, Shiqi Zhou, Peisi Li, Liheng Lin, Huake Yang, Ziyi Zhou, Linbo Jin, Xingyi Gan, Chenzheng Zhou, Zhen Cai, Taisong Pan, Min Gao, Dongli Fan, Yuan Lin, Yiming Zhang   +16 more
wiley   +1 more source

IKKβ and USP28 Regulate HEY1 Stability to Promote Cancer Stemness and Immune Evasion in Hepatocellular Carcinoma

Advanced Science, EarlyView.
The uncovered IKKβ‐USP28‐HEY1 axis fuels cancer stemness and immune evasion in hepatocellular carcinoma. USP28 deubiquitinates HEY1 upon IKKβ‐mediated phosphorylation, conferring PD‐1/PD‐L1 blockade resistance. Pharmacological inhibition of USP28 sensitizes resistant tumors to anti‐PD‐1 immunotherapy, revealing a promising therapeutic strategy ...
Na Shao, Lin Zhang, Gufang Shen, Yangfan Lv, Tianshu Fang, Ya Cao, Qiongyi Zhang, Feng Xu, Chungang Liu   +8 more
wiley   +1 more source

RhoA signaling modulates cyclin D1 expression in human lung fibroblasts; implications for idiopathic pulmonary fibrosis

Respiratory Research, 2006
Background Idiopathic Pulmonary Fibrosis (IPF) is a debilitating disease characterized by exaggerated extracellular matrix deposition and aggressive lung structural remodeling.
Hoban PR, Cottrell E, Watts KL, Spiteri MA   +3 more
doaj   +1 more source

CCT2 Promotes Prostate Cancer Progression Through EIF3F‐Dependent Stabilization of FASN

Advanced Science, EarlyView.
ABSTRACT Prostate cancer (PCa) is increasingly recognized to be driven by dysregulated lipid metabolism. Although fatty acid synthase (FASN) is highly expressed in PCa, the mechanisms governing FASN protein stability and its functional integration into oncogenic lipid metabolism remain poorly defined.
Shun Xu, Yifan Zhang, Haolin Li, Shengyu Zhao, Xiaoran Dai, Qili Xu, Mintian Fei, Chun Li, Zhihui Zou, Baojun Wang, Li Zhang, Hui Wang, Ligang Zhang, Chaozhao Liang   +13 more
wiley   +1 more source

Varying light regimes in naturally growing Jatropha curcus: pigment, proline and photosynthetic performance [PDF]

Journal of Stress Physiology & Biochemistry, 2010
Light stress is a major abiotic stress which adversely affects productivity of the plants. Tolerance to abiotic stresses is very complex, due to the intricate of interactions between stress factors and various molecular, biochemical and physiological ...
Wadhwa R., N. Kumari, V. Sharma
doaj  

Processing of D1 Protein: A Mysterious Process Carried Out in Thylakoid Lumen. [PDF]

Int J Mol Sci, 2022
Inagaki N.
europepmc   +1 more source

ProSiteHunter: A Unified Framework for Sequence‐Based Prediction of Protein‐Nucleic Acid and Protein‐Protein Binding Sites

Advanced Science, EarlyView.
This study proposed a unified sequence‐based framework for protein binding site prediction, which adopted a tri‐track semantic multi‐source feature fusion strategy to effectively capture diverse macromolecular interaction sites and further improved the accuracy of antibody‐antigen interaction prediction.
Dongliang Hou, Qihang Zhen, Zexin Lv, Xinyue Cui, Suhui Wang, Minghua Hou, Zhan Zhou, Xiaogen Zhou, Guijun Zhang   +8 more
wiley   +1 more source

Correlation between cyclin D1 expression and standard clinicopathological variables in invasive breast cancer in Eastern India

South Asian Journal of Cancer, 2015
Introduction: Breast cancer is the leading oncogenic threat in South-East Asian women showing an inexplicable biological aggressiveness. High expression of cyclin D1, a key molecule in breast cancer pathogenesis, has been shown by previous studies in the
Santanu Sarkar, Aditya Kanoi, Jayanta Bain, Rajarshi Gayen, Kashi Nath Das   +4 more
doaj   +1 more source

G870A Polymorphic Variants of CCND1 Gene and Cyclin D1 Protein Expression as Prognostic Markers in Laryngeal Lesions. [PDF]

Diagnostics (Basel), 2022
Kowalczyk MM, Barańska M, Fendler W, Borkowska EM, Kobos J, Borowiec M, Pietruszewska W.   +6 more
europepmc   +1 more source

Role of protein kinase D1 in pancreatic cancerogenesis

, 2021
The aim of this study was to characterize the effect of Protein Kinase D1 (PKD1) loss in an oncogenic KRASG12D-driven genetic mouse model of pancreatic cancer in vivo. We evaluated three mouse lines (p48-KRASG12D, p48-KRASG12D-PKD1−/− and p48-PKD1−/−) for cancer progression over a period of one year and detected a significant reduction of overall ...
openaire   +1 more source