Results 101 to 110 of about 254,547 (258)

SMYD3 Promotes Cell Cycle Progression by Inducing Cyclin D3 Transcription and Stabilizing the Cyclin D1 Protein in Medulloblastoma. [PDF]

open access: yesCancers (Basel), 2022
Asuthkar S   +8 more
europepmc   +1 more source

Role of protein kinase D1 in pancreatic cancerogenesis

open access: yes, 2021
The aim of this study was to characterize the effect of Protein Kinase D1 (PKD1) loss in an oncogenic KRASG12D-driven genetic mouse model of pancreatic cancer in vivo. We evaluated three mouse lines (p48-KRASG12D, p48-KRASG12D-PKD1−/− and p48-PKD1−/−) for cancer progression over a period of one year and detected a significant reduction of overall ...
openaire   +1 more source

Metabologenomic Hallmark‐Based Discovery of Bacterial Thioamides as a New Lead against Drug‐Resistant Pancreatic Cancer

open access: yesAdvanced Science, EarlyView.
A targeted metabologenomic strategy integrating genomic and metabolomic hallmarks enabled the discovery of two new thioamides, thiogochangamides A and B, from bacteria. Their absolute configurations, previously unresolved within the thioviridamide family, were fully assigned through various chemical derivatizations and computational analysis ...
Young Eun Du   +18 more
wiley   +1 more source

Fermented aquatic weed meal (FAWM) as a protein source in Asian Catfish Clarias batrachus diets: Impacts on growth, blood chemistry profile, liver and gut morphology and economic efficiency

open access: yesAquaculture Reports
The global aquaculture industry is increasingly seeking sustainable alternatives to fishmeal (FM) due to its high price and shortfall in supply. In this context, fermented aquatic weed meal (FAWM) could emerge as a viable plant protein source for ...
Talukdar Jannat Tamanna Shimul   +13 more
doaj   +1 more source

Protein expression patterns of cell cycle regulators in operable breast cancer.

open access: yesPLoS ONE, 2017
Background-aimTo evaluate the prognostic role of elaborate molecular clusters encompassing cyclin D1, cyclin E1, p21, p27 and p53 in the context of various breast cancer subtypes.MethodsCyclin E1, cyclin D1, p53, p21 and p27 were evaluated with ...
Flora Zagouri   +23 more
doaj   +1 more source

A BioLiving Periosteum Evokes Centripetal Regeneration in Challenging Bone Defects

open access: yesAdvanced Science, EarlyView.
Large bone defects often suffer from insufficient central healing. This study engineers a BioLiving periosteum that mimics the native structure. It sequentially delivers remote chemical cues and contact physical cues in a signaling‐relay manner, effectively recruiting and guiding endogenous cells toward the defect center.
Yang Shi   +12 more
wiley   +1 more source

Eucalyptus ESTs corresponding to the enzyme glutamine synthetase and the protein D1, sites of action of herbicides that cause oxidative stress

open access: yesGenetics and Molecular Biology, 2005
This work was aimed at locating Eucalyptus ESTs corresponding to the GS enzyme (Glutamine Synthetase, EC = 6.3.1.2) and to the D1 protein, which are directly related to resistance to herbicides that promote oxidative stress.
Edivaldo Domingues Velini   +9 more
doaj   +1 more source

Diversity of Pharmaceuticals Enhances Antibiotic Resistance in the Invertebrate Gut via Biofilm‐Mediated Mechanisms

open access: yesAdvanced Science, EarlyView.
Pharmaceutical diversity acts as an independent driver of antibiotic resistance in soil invertebrates. While bulk soil remains unaffected, the collembolan gut microbiome exhibits significant resistance gene enrichment under complex chemical exposure and diurnal warming.
Yi‐Fei Wang   +11 more
wiley   +1 more source

Effect of Ethanol Processing on Functional Properties and Composition of Peanut Proteins

open access: yesLiang you shipin ke-ji
The quality of peanut protein prepared under different ethanol processing conditions varies, leading to differences in protein properties and subsequently in the functional characteristics and applications of the protein products.
ZHANG Xiang-feng   +6 more
doaj   +1 more source

Home - About - Disclaimer - Privacy