Results 121 to 130 of about 10,757,883 (334)

Role of protein kinase D1 in pancreatic cancerogenesis

, 2021
The aim of this study was to characterize the effect of Protein Kinase D1 (PKD1) loss in an oncogenic KRASG12D-driven genetic mouse model of pancreatic cancer in vivo. We evaluated three mouse lines (p48-KRASG12D, p48-KRASG12D-PKD1−/− and p48-PKD1−/−) for cancer progression over a period of one year and detected a significant reduction of overall ...
openaire   +1 more source

MAPPING PROTEIN-PROTEIN INTERACTION DOMAINS IN WHEAT RHT-D1 [PDF]

Fusarium head blight (FHB) is a common fungal disease on wheat in western Canada, leading to loss of grain yield and reduced quality. Susceptibility to this disease has been linked to the presence of ‘Green Revolution’ alleles, Reduced height-B1b (Rht ...
Santiago, Lordwin
core  

m5C Reader ALYREF Promotes the Progression of Endometrial Cancer by Activating the XRCC6‐Mediated Wnt/β‐catenin Signaling Pathway

Advanced Science, EarlyView.
This study identifies ALYREF as an oncogenic m5C reader in endometrial cancer. ALYREF recognizes NSUN2‐mediated m5C modification on XRCC6 mRNA to enhance transcript stability and increase XRCC6 expression. Elevated XRCC6 activates Wnt/β‐catenin signaling, resulting in accelerated tumor cell proliferation, migration, invasion, and xenograft tumor growth.
Linlin Hao, Jian Zhang, Qi Qian, Min Jiang, Yu Liu, Yan Geng, Nan Cui, Qi Guo, Jie Guo   +8 more
wiley   +1 more source

The D1 protein of PSII is protected from damage caused by oxidative stress and severe dehydration.

, 2012
(A) Damage by the H2O2 treatments (H2O2) compared to control conditions (C). (B) Protection from damage by the dehydration treatments (DT). The DT samples were analyzed immediately after the dehydration treatment (0 h), and following rehydration for 16 h
Javier Tejedor-Cano (116100), Juan Jordano (116105), Antonio Diaz-Espejo (116103), Concepción Almoguera (116088), Marika Lindahl (116101), José-María Personat (116097), Pilar Prieto-Dapena (116092)   +6 more
core   +1 more source

A CD14‐Targeting In Situ Hydrogel Directs Macrophage Reprogramming to Minimize Scar Formation

Advanced Science, EarlyView.
A CD14‐targeting in situ hydrogel formed from a microbial polysaccharide rapidly remodels the immune microenvironment by reprogramming macrophage polarization, suppressing excessive inflammation, and coordinating tissue regeneration. This multifunctional hydrogel promotes scar‐reduced wound repair through enhanced angiogenesis, collagen remodeling, and
Rui Fang, Simeng Chen, Qiaozhen Liu, Wenwen Ni, Xi Xu, Jianfa Zhang   +5 more
wiley   +1 more source

G870A Polymorphic Variants of CCND1 Gene and Cyclin D1 Protein Expression as Prognostic Markers in Laryngeal Lesions. [PDF]

Diagnostics (Basel), 2022
Kowalczyk MM, Barańska M, Fendler W, Borkowska EM, Kobos J, Borowiec M, Pietruszewska W.   +6 more
europepmc   +1 more source

The AT-Hook Protein D1 Is Essential for Drosophila melanogaster Development and Is Implicated in Position-Effect Variegation [PDF]

, 2002
We have analyzed the expression pattern of the D1 gene and the localization of its product, the AT hook-bearing nonhistone chromosomal protein D1, during Drosophila melanogaster development.
Kaes, Emmanuel, Nathalie Aulner, Sam Janssen, Sall, Alhousseynou, Mandicourt, Guillaume, Monod Kas, Caroline, Alhousseynou Sall, Olivier Cuvier, Guillaume Mandicourt, Caroline Monod, Emmanuel Käs, Janssen, Samuel Théodoor, Denis Jullien, Jullien, Denis, Laemmli, Ulrich Karl, Aulner, Nathalie, Ulrich K. Laemmli, Cuvier, Olivier, Monod, Caroline, Laemmli, Ulrich K., Janssen, Sam, Käs, Emmanuel   +21 more
core   +1 more source

Glucocorticoid Receptor Signaling in Myeloid Cells Orchestrates Inflammation Resolution and Muscle Repair

Advanced Science, EarlyView.
Glucocorticoids (GC) are widely used to reduce inflammation. We show that the glucocorticoid receptor in myeloid cells regulates macrophage cell cycle and genome integrity during muscle regeneration. We demonstrate that dexamethasone administration during the early inflammatory phase delays muscle repair by increasing macrophage proliferation ...
Sirine Souali‐Crespo, Joe G. Rizk, Emilia Calvano, Rajesh Sahu, Emina Colovic, Imane Chabba, Valentine Gilbart, Erwan Grandgirard, Bastien Morlet, Qingshuang Cai, Daniel Metzger, Delphine Duteil   +11 more
wiley   +1 more source

Fermented aquatic weed meal (FAWM) as a protein source in Asian Catfish Clarias batrachus diets: Impacts on growth, blood chemistry profile, liver and gut morphology and economic efficiency

Aquaculture Reports
The global aquaculture industry is increasingly seeking sustainable alternatives to fishmeal (FM) due to its high price and shortfall in supply. In this context, fermented aquatic weed meal (FAWM) could emerge as a viable plant protein source for ...
Talukdar Jannat Tamanna Shimul, Parashuram Kallem, Shishir Kumar Nandi, Sadia Afrin, Afrina Yeasmin Suma, Zulhisyam Abdul Kari, Suniza Anis Mohamad Sukri, Martina Irwan Khoo, Nurdiyana Aqilah Roslan, Ajay Guru, Krishnakumar Velayudhannair, El-Sayed Hemdan Eissa, Md. Shahab Uddin, Muhammad Anamul Kabir   +13 more
doaj   +1 more source

Protein expression patterns of cell cycle regulators in operable breast cancer.

PLoS ONE, 2017
Background-aimTo evaluate the prognostic role of elaborate molecular clusters encompassing cyclin D1, cyclin E1, p21, p27 and p53 in the context of various breast cancer subtypes.MethodsCyclin E1, cyclin D1, p53, p21 and p27 were evaluated with ...
Flora Zagouri, Vassiliki Kotoula, George Kouvatseas, Maria Sotiropoulou, Triantafyllia Koletsa, Theofani Gavressea, Christos Valavanis, Helen Trihia, Mattheos Bobos, Georgios Lazaridis, Angelos Koutras, George Pentheroudakis, Pantelis Skarlos, Dimitrios Bafaloukos, Niki Arnogiannaki, Sofia Chrisafi, Christos Christodoulou, Pavlos Papakostas, Gerasimos Aravantinos, Paris Kosmidis, Charisios Karanikiotis, George Zografos, Christos Papadimitriou, George Fountzilas   +23 more
doaj   +1 more source