Results 91 to 100 of about 61,964 (279)

Cationized liposomal keto-mycolic acids isolated from Mycobacterium bovis bacillus Calmette-Guérin induce antitumor immunity in a syngeneic murine bladder cancer model.

PLoS ONE, 2019
Intravesical therapy using Mycobacterium bovis bacillus Calmette-Guérin (BCG) is the most established cancer immunotherapy for bladder cancer. However, its underlying mechanisms are unknown. Mycolic acid (MA), the most abundant lipid of the BCG cell wall,
Takayuki Yoshino, Jun Miyazaki, Takahiro Kojima, Shuya Kandori, Masanobu Shiga, Takashi Kawahara, Tomokazu Kimura, Takashi Naka, Hideyasu Kiyohara, Miyuki Watanabe, Sho Yamasaki, Hideyuki Akaza, Ikuya Yano, Hiroyuki Nishiyama   +13 more
doaj   +1 more source

How Social‐Symbolic Work Changes Places

Journal of Management Studies, EarlyView.
Abstract We advance the social‐symbolic work perspective by developing an understanding of places as objects characterized by location, materiality, function, and symbolic meaning and which can be changed through social‐symbolic work. Drawing from a longitudinal study of the ‘Empty Homes’ Programme in England, our analysis identifies an unfolding ...
April L. Wright, Richard Lang, Ewald Kibler   +2 more
wiley   +1 more source

The Modern Wholesaler: Global Sourcing, Domestic Distribution, and Scale Economies

Social Science Research Network
Half of all transactions in the $6 trillion market for manufactured goods in the United States were intermediated by wholesalers in 2012, up from 32 percent in 1992. Seventy percent of this increase is due to the growth of “superstar” firms—the largest 1
S. Ganapati
semanticscholar   +1 more source

Optimization of passenger flow control and parallel bus bridging in urban rail transit based on intelligent transport infrastructure

Computer-Aided Civil and Infrastructure Engineering, EarlyView.
Abstract Passenger flow control and bus bridging are used widely in the operations and management of urban rail transit to relieve the pressure of urban rail transit passenger flow, especially in peak periods. This paper presents an optimization method based on time‐varying running time in links.
Qingqing Zhao, Jinjin Tang, Wen‐Long Shang, Chao Li, Yifei Ren, Mohammed Quddus, Washington Ochieng   +6 more
wiley   +1 more source

Learning by Necessity: Government Demand, Capacity Constraints, and Productivity Growth

The American Economic Review
This paper studies how firms adapt to demand shocks when facing capacity constraints. I show that increases in government purchases raise total factor productivity in quantity units at the production line level.
Ethan Ilzetzki
semanticscholar   +1 more source

Manipulation of the Expression of Tryptophan Decarboxylase Boosts Grain Functional Quality and Stress Resilience Capacity of Wheat

Plant Biotechnology Journal, EarlyView.
ABSTRACT Tryptophan decarboxylase (TDC), the rate‐limiting enzyme of tryptophan metabolism in plants, is essential for the production of a series of bioactive molecules, such as serotonin, melatonin and the plant hormone indole‐3‐acetic acid and therefore plays crucial roles in various aspects of growth and development.
Haili Zhang, Qiulan Huang, Ling Yi, Juanyu Zhang, Qiang Li, Xiaona Song, Shujing Cheng, Peiyong Xin, Jinfang Chu, Guangbing Deng, Junjun Liang, Tao Li, Maoqun Yu, Hai Long   +13 more
wiley   +1 more source

Duckweeds: Model organisms for research on plant sterols and steroids

Plant Biology, EarlyView.
Duckweeds (Lemnaceae), the fastest‐growing angiosperms and promising vegan protein source, offer a powerful model to address key questions in plant physiology. This article highlights their potential for dissecting the biosynthesis and function of phytosterols, sterol conjugates, brassinosteroids, and specialized steroidal metabolites, such as ...
J. Klein, K.‐J. Appenroth, K. S. Sree
wiley   +1 more source

The relationship between the digital maturity and efficiency of Croatian non-life insurers: Exploratory research

Journal of Economics and Management
Aim/purpose – In line with the general trend of digitalization and changing customers’ needs and preferences, insurance companies have increasingly applied digital technology to their business.
Ćurak Marijana, Duvnjak Mirela, Pervan Maja   +2 more
doaj   +1 more source

Should I stay or should I go? Leveraging data‐driven approaches to explore the effect of various disaster policies on postearthquake household relocation decision‐making

Risk Analysis, EarlyView.
Abstract Devastating earthquakes can cause affected households to relocate. Postearthquake relocation disrupts impacted households' social ties and, in some instances, their access to affordable services. Simulation‐based approaches that model postearthquake relocation decision‐making can be valuable tools for supporting the development of related ...
Chenbo Wang, Gemma Cremen, Carmine Galasso   +2 more
wiley   +1 more source

Prerequisites for Business Development in South-Eastern Europe in the Conditions of Polycrisis and Digital Transformation

ECONOMICS
Purpose: The purpose of the present study is to identify prerequisites for business development in the conditions of polycrisis in the EU member states of South-Eastern Europe.
Hristozov Yanko, Nozharov Shteryo
doaj   +1 more source