Results 31 to 40 of about 1,312 (124)

Reducing data processing effort in camera trap density estimation: Extending the REST model by explicitly modelling animal detection processes

Methods in Ecology and Evolution, Volume 17, Issue 3, Page 850-862, March 2026.
Abstract Accurate and reliable estimation of wildlife population density is fundamental to effective conservation and management. While camera traps show potential for monitoring ground‐dwelling mammal densities, labour‐intensive data processing remains a significant constraint. Ideally, conservation efforts would benefit from the continuous monitoring
Yoshihiro Nakashima, Gota Yajima, Ryo Matsuoka   +2 more
wiley   +1 more source

Mutations in DNMT3B Modify Epigenetic Repression of the D4Z4 Repeat and the Penetrance of Facioscapulohumeral Dystrophy [PDF]

The American Journal of Human Genetics, 2016
Facioscapulohumeral dystrophy (FSHD) is associated with somatic chromatin relaxation of the D4Z4 repeat array and derepression of the D4Z4-encoded DUX4 retrogene coding for a germline transcription factor. Somatic DUX4 derepression is caused either by a 1-10 unit repeat-array contraction (FSHD1) or by mutations in SMCHD1, which encodes a chromatin ...
Boogaard, M.L. van den, Lemmers, R.J.L.F., Balog, J., Wohlgemuth, M., Auranen, M., Mitsuhashi, S., Vliet, P.J. van der, Straasheijm, K.R., Akker, R.F.P. van den, Kriek, M., Laurense-Bik, M.E.Y., Raz, V., Ostaijen-ten Dam, M.M. van, Hansson, K.B.M., Kooi, E.L. van der, Kiuru-Enari, S., Udd, B., Tol, M.J.D. van, Nishino, I., Tawil, R., Tapscott, S.J., Engelen, B.G.M. van, Maarel, S.M. van der   +22 more
openaire   +4 more sources

Interleukin‐6 as a Key Biomarker in Facioscapulohumeral Dystrophy: Evidence From Longitudinal Analyses

Annals of Clinical and Translational Neurology, Volume 13, Issue 2, Page 310-323, February 2026.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy type 1 (FSHD1) is a progressive neuromuscular disorder with no approved treatments. Identifying reliable biomarkers is critical to monitor disease severity, activity, and progression. Interleukin‐6 (IL‐6) has been proposed as a candidate biomarker, but longitudinal validation is limited ...
Jonathan Pini, Emanuela Martinuzzi, Sandra Dhifallah, Abderhmane Slioui, Angela Puma, Luisa Villa, Michele Cavalli, Andra Ezaru, Jérémy Garcia, Manuela Gambella, Federico Torre, Luca Jacopo Pavan, Nicolas Glaichenhaus, Sabrina Sacconi   +13 more
wiley   +1 more source

Development of a Four‐Language Questionnaire to Investigate Environmental Risk Factors for the Development of Canine Atopic Dermatitis and to Monitor Disease Course and Progression

Veterinary Dermatology, Volume 37, Issue 1, Page 34-44, February 2026.
Background: The chronic and multifactorial character of canine atopic dermatitis (cAD) often leads to poor disease control and treatment dissatisfaction. Environmental factors are likely to contribute to the disease development and may play a more important role than assumed previously.
Patricia Clara‐Maria Rhodius, Nina Fischer, Ana Rostaher, Franco Martini, Edwin Chapman, Sabrina Audergon, Stefan Hobi, Georg Lehner, Sylvie Wilhelm, Noëmi van Oordt, Claude Favrot, Malwina Kowalska   +11 more
wiley   +1 more source

Effect of a Spray Containing Occlusive Agents, Humectants and Physiological Lipids on Skin Hydration of Healthy Dogs When Applied After Bathing With a Chlorhexidine 2%/Miconazole 2% Shampoo

Veterinary Dermatology, Volume 37, Issue 1, Page 140-147, February 2026.
Background: Normal hydration of the canine epidermis is imperative for cutaneous homeostasis. Xerosis may be encountered in canine atopic dermatitis and may be aggravated by topical antiseptics. Hypothesis and Objectives: To evaluate the hydrating properties and the safety of a spray (Sensiderm spray; MP Labo) when applied after shampooing healthy dogs
Adamantia Pseftogka, Elisabeta Samuel (Badulescu), Manolis K. Chatzis, Manolis N. Saridomichelakis   +3 more
wiley   +1 more source

Evaluation of Chlorhexidine‐Containing Shampoos: In Vitro Efficacy Against Staphylococcus pseudintermedius and Lathering Ability

Veterinary Dermatology, Volume 37, Issue 1, Page 148-160, February 2026.
Background: The antibacterial efficacy of chlorhexidine shampoo is directly affected by formulation and bathing factors. Hypothesis/Objective: To evaluate the in vitro antibacterial efficacy of chlorhexidine‐containing shampoos at various dilutions and to compare their lathering ability.
Emily E. Binversie, Jason B. Pieper, Darren J. Berger   +2 more
wiley   +1 more source

Molecular Diagnosis in a Specialised Neurogenetic Clinic With Access to Whole‐Genome Sequencing

Acta Neurologica Scandinavica, Volume 2026, Issue 1, 2026.
Background Rare diseases, collectively affecting 1 in 17 people in the United Kingdom and Ireland, require coordinated care. Specialised multidisciplinary clinics offer a streamlined approach for diagnosis and management of rare neurogenetic disorders.
Patrick B. Moloney, Nicholas W. Wood, Rob Rouhl   +2 more
wiley   +1 more source

A family of facioscapulohumeral muscular dystrophy confirmed by D4Z4 deletion on chromosome 4q35

Journal of Medicine and Life Science, 2009
Facioscapulohumeral muscular dystrophy (FSHD). is an autosomal dominant form of muscular dystrophy characterized by progressive weakness and wasting of the facial. shoulder-girdle and upper arm muscles. Recently, FSHD is diagnosed by a molecular genetic test showing a deletion of integral copies to a 3.3 kb DNA repeat motif named D4Z4.
Jae Young Lee, Jee Young Kim, Joong-Goo Kim, Ji-Hoon Kang, Jay Chol Choi, Jung Seok Lee, Sa- Yoon Kang   +6 more
openaire   +1 more source

Transcriptional analysis of the human D4Z4 and mouse Dux arrays [PDF]

, 2012
Facioscapulohumeral muscular dystrophy (FSHD) is the third most common form of muscular dystrophy in Caucasians. FSHD is caused by contraction of a 3.3kb repeat array, D4Z4, to below 11 repeat units. Each of these repeat units contains an ORF encoding the DUX4 gene and at the beginning of the work described in this thesis expression of transcripts from
openaire   +1 more source

Post-transcriptional RNA stabilization of telomere-proximal RNAs FRG2, DBET, D4Z4 at human 4q35 in response to genotoxic stress and D4Z4 macrosatellite repeat length

ABSTRACT Background Reduced copy number of the D4Z4 macrosatellite at human chromosome 4q35 is associated with facioscapulohumeral muscular dystrophy (FSHD). A pervasive idea is that chromatin alterations at the 4q35 locus following D4Z4 repeat unit deletion lead to disease via inappropriate ...
Valentina Salsi, Francesca Losi, Monica Salani, Paul D. Kaufman, Rossella Tupler   +4 more
openaire   +1 more source