Results 41 to 50 of about 151 (87)

Bacteriophage and Fusidic Acid Have Synergistic Effect Against Meticillin‐Resistant Staphylococcus pseudintermedius in Ex Vivo Canine Dermis Model

Veterinary Dermatology, Volume 37, Issue 2, Page 200-210, April 2026.
Background: Antimicrobial stewardship has become vital given the progressive emergence of multidrug‐resistant bacteria, and novel approaches to the treatment of bacterial infections are needed. Recently, reported synergistic effects of antibacterial drugs and bacteriophage therapy have revealed promising applications for the management of meticillin ...
Sarah Ehling, Elisa Peh, Hilke Oltmanns, Jessica Meissner, Sophie Kittler, Christina Puff, Jutta Verspohl, Mathias Müsken, Madeleine Plötz, Andrea Vanessa Volk   +9 more
wiley   +1 more source

New Insights into Genotype-phenotype Correlations in Chinese Facioscapulohumeral Muscular Dystrophy: A Retrospective Analysis of 178 Patients

Chinese Medical Journal, 2015
Background: Facioscapulohumeral muscular dystrophy (FSHD), a common autosomal dominant muscular disorder, is caused by contraction of the D4Z4 repeats on 4q35.
Feng Lin, Zhi-Qiang Wang, Min-Ting Lin, Shen-Xing Murong, Ning Wang   +4 more
doaj   +1 more source

Machine Learning Model for an App‐Based Tool to Assist With the Diagnosis of Canine Atopic Dermatitis

Veterinary Dermatology, Volume 37, Issue 2, Page 236-246, April 2026.
Canine atopic dermatitis (cAD) is a chronic condition requiring life‐long management. Accurate diagnosis can be challenging, with no reliable diagnostic test. This study aimed to generate a simple diagnostic model for cAD. This model is a relevant prototype for an app‐based tool to support general practitioners in the diagnosis of cAD alongside ...
Xavier Langon, Mathieu Montoya, Isabelle Gourdon   +2 more
wiley   +1 more source

A Novel Topical Emollient Plus for Canine Atopic Dermatitis: A Clinical Trial Assessing Efficacy and User Acceptance

Veterinary Dermatology, Volume 37, Issue 2, Page 293-305, April 2026.
Background: Canine atopic dermatitis (cAD) is a common, chronic skin condition characterised by epidermal barrier dysfunction, immune dysregulation and cutaneous dysbiosis. While “emollient plus” formulations are widely used in human atopic dermatitis, their role in cAD remains underexplored. Hypothesis/Objectives: To evaluate the clinical efficacy and
Beatriz Fernandes, António Caldeira Mendes, Susana Paula Alves, Vanessa Schmidt, Ana Filipa Bizarro, Marta Pinto, Hugo Pereira, Joana Marto, Ana Mafalda Lourenço   +8 more
wiley   +1 more source

Replication timing of human telomeres is chromosome arm-specific, influenced by subtelomeric structures and connected to nuclear localization. [PDF]

PLoS Genetics, 2010
The mechanisms governing telomere replication in humans are still poorly understood. To fill this gap, we investigated the timing of replication of single telomeres in human cells.
Nausica Arnoult, Caroline Schluth-Bolard, Anne Letessier, Irena Drascovic, Rachida Bouarich-Bourimi, Judith Campisi, Sahn-Ho Kim, Amina Boussouar, Alexandre Ottaviani, Frédérique Magdinier, Eric Gilson, Arturo Londoño-Vallejo   +11 more
doaj   +1 more source

Efficacy of Der f 2/Zen 1‐LAMP1 Plasmid‐Based Vaccine Immunotherapy in Dogs With Atopic Dermatitis: A Proof‐of‐Concept Study

Veterinary Dermatology, Volume 37, Issue 2, Page 306-318, April 2026.
Background: DNA‐based vaccination rapidly induces strong cellular and humoral immune responses, which may be enhanced by inclusion of lysosomal‐associated membrane protein‐1 (LAMP). Objectives: This proof‐of‐concept study evaluated the efficacy and safety of a Der f 2/Zen 1‐LAMP‐based DNA vaccine immunotherapy in client‐owned dogs with nonseasonal AD ...
Petra Bizikova, Chigusa Matsumoto, Shoji Ogino, Toshihiro Tsukui, Kim Love, Marcy Murphy, Ina Herrmann   +6 more
wiley   +1 more source

Randomised, Double‐Blinded, Placebo‐Controlled Challenge Test With Single Food Items in Dogs With Atopic Dermatitis and Adverse Food Reactions

Veterinary Dermatology, Volume 37, Issue 2, Page 247-256, April 2026.
ABSTRACT Background Identification of offending foods in dogs with adverse food reactions is usually based on “deterioration” during open food challenges. Objectives To examine the placebo effect during double‐blinded, placebo‐controlled food challenges using a predefined set of criteria for relapse.
Evi I. Sofou, Elisa Samuel, Svetlina Aleksandrova, Manolis Chatzis, Manolis N. Saridomichelakis   +4 more
wiley   +1 more source

Expanding the Differential Diagnosis of Ultrasonographic Flexor Digitorum Profundus–Flexor Carpi Ulnaris Dissociation of Echogenicity: Muscular Dystrophies

Muscle &Nerve, Volume 73, Issue 3, Page 485-489, March 2026.
ABSTRACT Introduction/Aims Dissociation of echogenicity of the flexor digitorum profundus (FDP) and flexor carpi ulnaris (FCU) on neuromuscular ultrasound has been reported to be a useful sign to differentiate inclusion body myositis (IBM) from more common disease mimics, but it is not clear that this finding is pathognomonic of IBM. Our study aimed to
Anson W. Wilks, Nizar Chahin
wiley   +1 more source

Correlation analysis between genotype and phenotype of patients with facioscapulohumeral muscular dystrophy type 1

Chinese Journal of Contemporary Neurology and Neurosurgery, 2019
Objective To investigate the clinical phenotype and genotype of facioscapulohumeral muscular dystrophy type 1 (FSHD1) and the correlation between the two.
Huan LI, Qiu CHEN, Jin-fu LIN, Zi-yu LIAO, Liang WANG, Jing LI, Yu-ling ZHU, Cheng ZHANG   +7 more
doaj  

Pathomechanisms and biomarkers in facioscapulohumeral muscular dystrophy: roles of DUX4 and PAX7

EMBO Molecular Medicine, 2021
Facioscapulohumeral muscular dystrophy (FSHD) is characterised by progressive skeletal muscle weakness and wasting. FSHD is linked to epigenetic derepression of the subtelomeric D4Z4 macrosatellite at chromosome 4q35.
Christopher R S Banerji, Peter S Zammit
doaj   +1 more source