Results 41 to 50 of about 462 (98)
Frontiers in Medicine, 2023 BackgroundSevere fever with thrombocytopenia syndrome (SFTS) is an emerging and life-threatening infectious disease caused by SFTS virus. Although recent studies have reported the use of nomograms based on demographic and laboratory data to predict the ...
Zhenxing Li, Zhaoru Zhang, Chong Chen
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Global Change Biology, Volume 29, Issue 23, Page 6647-6660, December 2023., 2023 We use an integrated multi‐model, multi‐scenario framework to assess the impact of global climate change on SFTS disease in the mainland of China. The SFTS incidence in three time periods (2030–2039, 2050–2059, and 2080–2089) is predicted to be increased as compared to the 2010s in the context of various RCPs.
Fang‐Yu Ding +11 more
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Biosafety and Health, 2022 Phenuiviridae, a member of the Bunyavirales order, can lead to significant human morbidity and mortality. Various phenuiviruses target specific cellular proteins and have strategies to counteract the effects of type I interferon (IFN).
Leling Xu +5 more
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Humoral immunity to phlebovirus infection
Annals of the New York Academy of Sciences, Volume 1530, Issue 1, Page 23-31, December 2023., 2023 Phleboviruses are global zoonotic pathogens that can cause severe disease when transmitted to humans. Here we discuss how studying antibody responses during natural infection and the identification of neutralizing epitopes on the mature polyproteins Gn and Gc are informing the development of phlebovirus vaccines.
Katie J. Doores
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SFTSV Gn‐Head mRNA vaccine confers efficient protection against lethal viral challenge
Journal of Medical Virology, Volume 95, Issue 11, November 2023., 2023 Abstract Severe fever with thrombocytopenia syndrome virus (SFTSV) is an emerging tick‐borne virus, causing thrombocytopenia and hemorrhagic fever, with a fatality rate ranging from 12% to 30%. SFTSV possesses Gn and Gc glycoproteins, which are responsible for host cell receptor attachment and membrane fusion, respectively, to infect host cells.
Dokyun Kim +6 more
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Virology Journal, 2023 Background Severe fever with thrombocytopenia syndrome (SFTS) is an infectious disease caused by the Dabie bandavirus, [or SFTS virus (SFTSV)] that has become increasingly widespread since it was first reported in 2009.
Kyungha Lee +4 more
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International Journal of Infectious Diseases, 2022 We report the administration of an anti-interleukin (IL)-6 antibody in a case of severe fever with thrombocytopenia syndrome (SFTS) with an increase in IL-6. On the day of admission, SFTS viral load and IL-6 concentration were 93 831 copies/ml and 5.4 pg/
Jeong Rae Yoo +4 more
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Angewandte Chemie, Volume 136, Issue 47, November 18, 2024.The demand for robust antiviral approaches is underscored by the continued COVID‐19 spread. SARS‐CoV‐2 Nsp1, highly conserved among SARS‐CoV‐2 variants, plays a pivotal role in controlling host protein expression and viral RNA translation. A small‐molecule Nsp1 inhibitor exhibited antiviral activity against various sarbecoviruses, signifying a ...
Wan Gi Byun +7 more
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Disease X Testing: The results of an international external quality assessment exercise
Journal of Biosafety and Biosecurity, 2022 The United Nations Secretary-General Mechanism (UNSGM) for investigation of the alleged use of chemical and biological weapons is the only established international mechanism of this type under the UN. The UNGSM may launch an international investigation,
Tian Qin +16 more
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Infection and Drug Resistance, 2022 Yin Zhang, Ying Huang, Yuanhong Xu Department of Clinical Laboratory, The First Affiliated Hospital of Anhui Medical University, Hefei, People’s Republic of ChinaCorrespondence: Yuanhong Xu; Ying Huang, Department of Clinical Laboratory, The First ...
Zhang Y, Huang Y, Xu Y
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