According to recent guidelines, oral dabigatran etexilate is indicated for stroke and systemic embolism prevention in patients with atrial fibrillation (AF). Aim.
Yu. B. Belousov +3 more
doaj +3 more sources
In Vitro Selection of Specific DNA Aptamers Against the Anti-Coagulant Dabigatran Etexilate. [PDF]
Aljohani MM +7 more
europepmc +3 more sources
How we treat bleeding associated with direct oral anticoagulants [PDF]
Direct oral anticoagulants are at least as effective as vitamin K antagonists for the prevention and treatment of thromboembolism. Unfortunately, differently from vitamin K antagonists, they have the great drawback of lacking specific antidotes in the ...
Franchini, Massimo +4 more
core +1 more source
Dental management of patients taking novel oral anticoagulants (NOAs): dabigatran [PDF]
A new group of oral anticoagulants (dabigatran, rivaroxaban, apixaban and edoxaban) with clear advantages over classic dicoumarin oral anticoagulants (warfarin and acenocoumarol) has been developed in recent years.
Albaladejo Martínez, Alberto +2 more
core +4 more sources
Monitoring the use of dabigatran etexilate for stroke prevention: compliance with renal function guidelines [PDF]
INTRODUCTIONDabigatran etexilate has become widely used in New Zealand, but information relating to when renal function monitoring is being undertaken is lacking.
Alesha J. Smith +3 more
doaj
Preclinical testing of dabigatran in trypsin-dependent pancreatitis
Pancreatitis, the inflammatory disorder of the pancreas, has no specific therapy. Genetic, biochemical, and animal model studies revealed that trypsin plays a central role in the onset and progression of pancreatitis.
Zsófia Gabriella Pesei +5 more
doaj +1 more source
Determination of Dabigatran Concentration in Human Plasma and Breast Milk
Venous thromboembolism (VTE) is an important cause of death following childbirth. Dabigatran etexilate can be a useful prophylaxis in susceptible women during the postpartum period. However, it is not clear whether dabigatran is excreted into breast milk
F. Sidgwick +4 more
doaj +1 more source
Correlation Between Trough Plasma Dabigatran Concentrations and Estimates of Glomerular Filtration Rate Based on Creatinine and Cystatin C [PDF]
AIMS: Dabigatran is largely cleared by renal excretion. Renal function is thus a major determinant of trough dabigatran concentrations, which correlate with the risk of thromboembolic and haemorrhagic outcomes.
Berit P. Jensen +8 more
core +1 more source
Critical appraisal of dabigatran in the treatment of deep vein thrombosis and pulmonary embolism [PDF]
Objective To compare the safety and efficacy of dabigatran to warfarin for the treatment of deep vein thrombosis and pulmonary embolism. Background Venous thromboembolism (VTE) is a disease comprised of two conditions: deep vein thrombosis and pulmonary
Dixon, Dave L., Ogbonna, Kelechi C.
core +3 more sources
Use of idarucizumab for emergency surgery in patients taking dabigatran
This article presents modern possibilities for the provision of emergency surgical care to patients with atrial fibrillation, who administered dabigatran etexilate.
O. M. Nesterova +5 more
doaj +1 more source

