Results 151 to 160 of about 20,750 (203)

Preoperative ultrasound before sentinel lymph node biopsy in melanoma in the era of neoadjuvant treatment: a systematic review and meta-analysis of diagnostic performance and cost analysis. [PDF]

EClinicalMedicine
van den Broek JA, Schurink AW, Leeneman B, Brabander T, van der Veldt AAM, Verhoef C, Grünhagen DJ.   +6 more
europepmc   +1 more source

A phase 1 dose-escalation and expansion study of binimetinib (MEK162), a potent and selective oral MEK1/2 inhibitor [PDF]

, 2017
et al,, Tan, Benjamin R
core   +2 more sources

Precision oncology in a dish: patient-derived glioma organoids to guide novel therapeutic strategies. [PDF]

Biomark Res
Monago-Sánchez A, Mateos-Madrigal L, Carrión-Navarro J, Hernández-Martínez A, Martínez-Riveiro C, Castelló-Pons M, Pacheco-Fuenmayor MV, Gutiérrez-González R, Lomillos-Prieto N, Prat-Acín R, Mathieu SG, Aracil-González C, Pérez-Núñez A, Pérez-Rodríguez F, Sánchez-Gómez P, Martín-Jouve B, Sánchez-López AJ, García-Romero N, Ayuso-Sacido Á.   +18 more
europepmc   +1 more source

MAPK-driven epithelial cell plasticity drives colorectal cancer therapeutic resistance. [PDF]

Nature
White M, Mills ML, Millett LM, Gilroy K, Hong Y, Zeiger LB, Simpson RJ, Corry SM, Ligeza A, Lannagan TRM, Susanti S, Ridgway RA, Yazgili AS, Grzesiak L, Amirkhah R, Ford CA, Vlahov N, Tovell H, Officer-Jones L, Ficken C, Pennie R, Najumudeen AK, Raven A, Nasreddin N, Chauhan E, Papanastasiou AS, Nixon C, Morrison V, Jackstadt R, Graham JS, Miller CJ, Ross SJ, Barry ST, Pavet V, Wilson RH, Le Quesne J, Dunne PD, Tejpar S, Leedham S, Campbell AD, Sansom OJ.   +40 more
europepmc   +1 more source

Efficacy and safety of BRAF-MEK inhibitors in treatment of Chinese patients with papillary craniopharyngioma: A retrospective cohort study. [PDF]

Mol Ther Oncol
Han R, Yan X, Yao B, Cai B, Qiao N, Ma Z, Ye Z, Gu X, Ye Z, Liang B, Chen Z, He W, Yu Y, Cao X, Cheng H, Chen H, Wang Y, Ye H, Zhang Z, Zhao Y, Huang R, Zhang Q.   +21 more
europepmc   +1 more source

NOX4-derived oxidative DNA damage impairs thyroid differentiation through an epigenetic mechanism in BRAF-mutated radioactive iodine refractory papillary thyroid cancer cells. [PDF]

Int J Biol Sci
Radom M, Buffet C, Cazarin J, Harinquet M, de Faria CC, Brayé F, Nobre C, Aglave M, Mesloub Y, Dayris T, Droin N, Godefroy K, Bani MA, Ghuzlan AA, Leboulleux S, Lamartina L, Dupuy C.   +16 more
europepmc   +1 more source

Targeting the MAPK Pathway in Brain Tumors: Mechanisms and Therapeutic Opportunities. [PDF]

Cancers (Basel)
Vrachas D, Kosma E, Giannopoulou AI, Margoni A, Gargalionis AN, El-Habr EA, Piperi C, Adamopoulos C.   +7 more
europepmc   +1 more source

Inhibiting Fatty Acid Oxidation Suppresses Acquired Resistance to Standard Chemotherapy in Melanoma. [PDF]

Int J Mol Sci
Choi W, Ham W, Park JH, Sim SH, Chun JW, Kang M, Kim C, Hong W, Koh EB, Kang JH, Woo SM, Kim SY.   +11 more
europepmc   +1 more source

Tumor microenvironment-guided targeted and immunotherapy in anaplastic thyroid cancer: a literature review from preclinical models to clinical translation. [PDF]

Transl Cancer Res
Kang H, Wu S, Gong H, Li F.
europepmc   +1 more source

Encorafenib plus binimetinib versus dabrafenib plus trametinib for the first-line treatment of patients with BRAF^V600E-mutant metastatic non-small cell lung cancer: a matching-adjusted indirect treatment comparison. [PDF]

ESMO Open
Planchard D, Mazières J, Grouin JM, Le Reun C, Luttenauer H, Boussahoua M, Macabeo B.   +6 more
europepmc   +1 more source