Results 51 to 60 of about 141 (84)

Cryo-EM Structure of the Human Amylin 1 Receptor in Complex with CGRP and Gs Protein. [PDF]

Biochemistry
Cao J, Belousoff MJ, Danev R, Christopoulos A, Wootten D, Sexton PM.   +5 more
europepmc   +1 more source

Prolonged signaling of backbone-modified glucagon-like peptide-<b>1</b> analogues with diverse receptor trafficking. [PDF]

Proc Natl Acad Sci U S A
Cary BP, Hager MV, Mariam Z, Morris RK, Belousoff MJ, Deganutti G, Sexton PM, Wootten D, Gellman SH.   +8 more
europepmc   +1 more source

Amylin: From Mode of Action to Future Clinical Potential in Diabetes and Obesity. [PDF]

Diabetes Ther
Volčanšek Š, Koceva A, Jensterle M, Janež A, Muzurović E.   +4 more
europepmc   +1 more source

Amylin, Another Important Neuroendocrine Hormone for the Treatment of Diabesity. [PDF]

Int J Mol Sci
Eržen S, Tonin G, Jurišić Eržen D, Klen J.   +3 more
europepmc   +1 more source

Conformational Dynamics of Amylin Receptors Revealed by Hydrogen-Deuterium Exchange Mass Spectrometry. [PDF]

J Am Chem Soc
Fairweather CJ, Zhang X, Fernando CD, Garama DJ, Sexton PM, Wootten D, Josephs TM.   +6 more
europepmc   +1 more source

Molecular Mechanisms of Islet Amyloid Polypeptide Aggregation: Towards Chemical Strategies to Prevent Amyloid Formation and to Design Non-Aggregating Peptide Therapeutics. [PDF]

Int J Mol Sci
Bousch C, Bérubé F, Babych M, Ongeri S, Bourgault S.   +4 more
europepmc   +1 more source

Lipid-Dependent Activation of the Orphan G Protein-Coupled Receptor, GPR3. [PDF]

Biochemistry
Russell IC, Zhang X, Bumbak F, McNeill SM, Josephs TM, Leeming MG, Christopoulos G, Venugopal H, Flocco MM, Sexton PM, Wootten D, Belousoff MJ.   +11 more
europepmc   +1 more source

Evolving Approaches for Pharmacological Therapy of Obesity. [PDF]

Annu Rev Pharmacol Toxicol
Chao AM, Taylor S, Moore M, Amaro A, Wadden TA.   +4 more
europepmc   +1 more source

Amylin - Its role in the homeostatic and hedonic control of eating and recent developments of amylin analogs to treat obesity. [PDF]

Mol Metab, 2018
Boyle CN, Lutz TA, Le Foll C.
europepmc   +1 more source

Oral glucagon-like peptide-1 receptor agonists and combinations of entero-pancreatic hormones as treatments for adults with type 2 diabetes: where are we now? [PDF]

Expert Opin Pharmacother
Gogineni P, Melson E, Papamargaritis D, Davies M.   +3 more
europepmc   +1 more source