Results 61 to 70 of about 57,080 (289)
, 2020 Additional file 4: Figure S3. Expression and purification of recombinant Hco-DAF-8 protein of H. contortus and immunoblot analysis. a Prokaryotic expression of recombinant protein Hco-DAF-8.
Jia-Nan Shan (8669883) +9 more
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Haplotype‐Resolved 3D Genomic Landscapes and Their Impacts on Agronomic Traits in Grapevine
Advanced Science, EarlyView.This study presents a haplotype‐resolved 3D genomic landscape of grapevine, revealing that structural variations (SVs) are closely associated with phased topologically associating domain (TAD) boundary transitions. These rearrangements coordinate with allele‐specific DNA methylation (ASM) and allele‐biased gene expression (ASE) to shape key agronomic ...
Yanling Peng +18 more
wiley +1 more source
iScience, 2021 Summary: Previous studies have revealed the importance of inter-tissue communications for lifespan regulation. However, the inter-tissue network responsible for lifespan regulation is not well understood, even in a simple organism Caenorhabditis elegans.
Masaharu Uno +8 more
doaj +1 more source
daf-2, daf-16 and daf-23: genetically interacting genes controlling Dauer formation in Caenorhabditis elegans. [PDF]
Genetics, 1994 Abstract Under conditions of high population density and low food, Caenorhabditis elegans forms an alternative third larval stage, called the dauer stage, which is resistant to desiccation and harsh environments. Genetic analysis of some dauer constitutive (Daf-c) and dauer defective (Daf-d) mutants has revealed a complex pathway that is
S, Gottlieb, G, Ruvkun
openaire +2 more sources
DAF-16 target gene enrichment in mitochondrial mutants.
, 2018 clk-1, isp-1 and nuo-6 mutants exhibit a highly significant overlap with daf-2 mutants and enrichment of DAF-16 target genes. The number of genes exhibiting a significant change in expression for each strain are shown in brackets.
Megan J. Bowman (494079) +7 more
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DAF-16 is unlikely to bind the col-19 promoter to regulate transcription.
, 2021 (A) Genetic region upstream of mtl-1, a confirmed transcriptional target of DAF-16 [52,53]. DNA sequence beginning immediately 3’ to W02F12.8, the gene upstream of mtl-1 is shown.
Margaret R. Starostik (11708055) +17 more
core +1 more source
Advanced Science, EarlyView.This work proposes a novel strategy to fabricate unimolecular pyroptosis photoinitiators activated by deep‐red light at low light doses. It relies on a photosensitization mechanism to trigger nitric oxide (NO) release from benzisothiadiazole‐based N‐nitrosanilines without modification of nitro moieties, thereby boosting pyroptosis‐mediated ...
Chuangxin Zhang +4 more
wiley +1 more source
DAF-16 is required for the longevity of clk-1, isp-1 and daf-2 worms.
, 2018 The long lifespan of clk-1 (A), isp-1 (B) and daf-2 (C) mutants is reduced to wild-type by the daf-16(mu86) deletion mutation. D. The daf-16(m26) point mutation also decreases isp-1 lifespan but to a lesser extent than the mu86 deletion mutation. P-value
Megan J. Bowman (494079) +7 more
core +1 more source
Advanced Science, EarlyView.It is innovatively utilized single‐cell RNA sequencing to explore the underlying causes of diabetes mellitus‐induced erectile dysfunction, followed by machine learning‐driven design of a single‐atom nanozyme (Fe‐DMOF) for precision treatment of erectile dysfunction.
Xiang Zhou +8 more
wiley +1 more source
DAF-16 regulates taste avoidance learning in ASER independently of the DAF-2c pathway.
, 2019 (A, B) Salt chemotaxis after conditioning under starvation with high (A) or low (B) salt (N = 8). A red or blue dot represents a chemotaxis index obtained from each trial after conditioning with high or low salt, respectively.
Takashi Nagashima (200207) +2 more
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