Breast cancer (BC) is one of the most challenging cancers to treat. Nutraceuticals acting by attenuating Hedgehog, NF‐κB, and Wnt/β‐catenin pathways. Nutraceuticals have medical characteristics and may cure cancer Abstract Breast cancer (BC) is one of the most challenging cancers to treat, accounting for many cancer‐related deaths.
Khalid Saad Alharbi+11 more
wiley +1 more source
Engineering plant immune circuit: walking to the bright future with a novel toolbox
Generating and developing disease‐resistant plant varieties are required to maintain a sustainable food stockpile and the environment. The ability to engineer immune regulatory components through several approaches, such as genetic transformation, CRISPR/Cas‐mediated gene knockdown/knockout, decoy engineering, pathogen effector‐based strategy, RNAi ...
Uyen Thi Vuong+6 more
wiley +1 more source
Plasma bioavailability and changes in PBMC gene expression after treatment of ovariectomized rats with a commercial soy supplement [PDF]
The health effects of soy supplementation in (post)menopausal women are still a controversial issue. The aim of the present study was to establish the effect of the soy isoflavones (SIF) present in a commercially available supplement on ovariectomized ...
Andres+63 more
core +7 more sources
Enhancement of developmentally regulated daidzein secretion from soybean roots in field conditions as compared with hydroponic culture [PDF]
Analyses of metabolite secretions by field-grown plants remain scarce. We analyzed daidzein secretion by field-grown soybean. Daidzein secretion was higher during early vegetative stages than reproductive stages, a trend that was also seen for ...
Hamamoto, Shoichiro+6 more
core +1 more source
Insect-induced daidzein, formononetin and their conjugates in soybean leaves. [PDF]
In response to attack by bacterial pathogens, soybean (Gylcine max) leaves accumulate isoflavone aglucones, isoflavone glucosides, and glyceollins. In contrast to pathogens, the dynamics of related insect-inducible metabolites in soybean leaves remain ...
Aboshi, Takako+10 more
core +1 more source
Collectively, plants contain several different families of natural products among which are compounds with weak estrogenic or antiestrogenic activity toward mammals.
Adlercreutz H+37 more
core +1 more source
Preliminary investigation of the influence of long-term dietary isoflavone intake on reproductive tract histology and sex steroid receptor expression in female domestic cats (Felis catus) [PDF]
Genistein and daidzein are isoflavones which are reported to influence the reproductive system in a variety of mammalian species. This pilot study aimed to determine if dietary isoflavones could potentially influence reproductive tract histology or ...
Cave, NJ+4 more
core +1 more source
Preliminary investigation of the influence of long-term dietary isoflavone intake on puberty onset and oestrous cycles in domestic cats (Felis catus) [PDF]
Genistein and daidzein are isoflavones which are reported to influence the reproductive system in a variety of mammalian species. This pilot study aimed to determine if dietary isoflavones could potentially influence reproductive parameters in domestic ...
Cave, NJ+3 more
core +1 more source
The Dietary Isoflavone Daidzein Reduces Expression of Pro-Inflammatory Genes through PPARα/γ and JNK Pathways in Adipocyte and Macrophage Co-Cultures. [PDF]
Obesity-induced inflammation caused by adipocyte-macrophage interactions plays a critical role in developing insulin resistance, and peroxisome proliferator-activated receptors (PPARs) regulate inflammatory gene expression in these cells.
Yuri Sakamoto+5 more
doaj +1 more source
Neuroprotective effects of daidzein on focal cerebral ischemia injury in rats
Daidzein, a plant extract, has antioxidant activity. It is hypothesized, in this study, that daidzein exhibits neuroprotective effects on cerebral ischemia.
Adem Bozkurt Aras+8 more
doaj +1 more source