Results 71 to 80 of about 18,663 (157)

Honokiol‐Magnolol‐Baicalin Possesses Synergistic Anticancer Potential and Enhances the Efficacy of Anti‐PD‐1 Immunotherapy in Colorectal Cancer by Triggering GSDME‐Dependent Pyroptosis

Advanced Science, Volume 12, Issue 13, April 3, 2025.
In this study, Honokiol (H)‐magnolol (M)‐baicalin (B) is identified as the primary active ingredients of Huangqin Houpo decoction. The HMB combination not only possesses potent synergistic anticancer activity, but also enhances the effectiveness of anti‐PD‐1 immunotherapy by inducing GSDME‐dependent pyroptosis in CRC cells.
Quan Gao, Qinsong Sheng, Zijing Yang, ZhiYu Zhu, Lin Li, Lihui Xu, Jing Xia, Yunhao Qiao, Jie Gu, Xiaolong Zhu, Tian Xie, Xinbing Sui   +11 more
wiley   +1 more source

The Anti-apoptosis Effects of Daidzein in the Brain of D-Galactose Treated Mice

Molecules, 2007
The purpose of this study was to explore the neuroprotective effects of daidzein on the apoptotic pathway in the hippocampus and cortex of D-galactose treated mice. For this purpose we have examined the expression of bcl-2 mRNA, bax mRNA and caspase-3 in
Xiang-bin Hu, Qing Chang, Xiao-wan Zhu, Bao-ping Han, Yan-qiu Zhang, Yuan-lin Zheng, Zhen Mao   +6 more
doaj   +1 more source

Novel daidzein analogs enhance osteogenic activity of bone marrow-derived mesenchymal stem cells and adipose-derived stromal/stem cells through estrogen receptor dependent and independent mechanisms [PDF]

, 2014
INTRODUCTION: Osteoporosis is a disease characterized by low bone mineral density (BMD) and increased risk of fractures. Studies have demonstrated the use of phytoestrogens, or plant-derived estrogens, such as genistein and daidzein, to effectively ...
Boue, Stephen M, Bunnell, Bruce A, Burow, Matthew E, Elliott, Steven, Gimble, Jeffrey M, Jiang, Quan, Ohlstein, Jason F, Strong, Amy L, Wang, Guangdi, Zhang, Qiang, Zheng, Shilong   +10 more
core   +1 more source

Tailoring enhanced production and identification of isoflavones in the callus cultures of Pueraria thomsonii Benth and its model verification using response surface methodology (RSM): a combined in vitro and statistical optimization

Beni-Suef University Journal of Basic and Applied Sciences, 2022
Background Scientifically, isoflavones from Pueraria thomsonii Benth possess diverse pharmacological activities and have been used to treat various diseases.
Yu Li, Pachaiyappan Saravana Kumar, Yu Liu, Jiao Qiu, Yalan Ran, Mingyuan Yuan, Xinyue Fang, Xuhui Tan, Renjun Zhao, Ji zhu, Meijun He   +10 more
doaj   +1 more source

Simultaneous Electrochemical Detection of Puerarin and Daidzein by Ag Nanoparticles and CuO Nanowires Coated ZnO Nanorod Arrays Self‐Supporting Electrode

ChemElectroChem, Volume 12, Issue 7, April 1, 2025.
A composite electrode, AgNP‐CuONW/ZnONR@CFP, was fabricated using a hydrothermal method and chemical deposition for detecting puerarin and daidzein in tablets. The sensor shows a low detection limit, wide linear range, and good stability for simultaneous detection of both compounds. It holds potential for analyzing actual pharmaceuticals.
Jiaqiang Liu, Qi Ai, Yuanxia Zuo, Xinhui Zhao, Qilong Wu, Mingyan Wang, Jun Chen   +6 more
wiley   +1 more source

Anti-inflammatory and anti-oxidative activities of daidzein and its sulfonic acid ester derivatives

Journal of Functional Foods, 2017
To improve the activity of the isoflavone daidzein (1) and to explore its structure-activity relationship, new daidzein sulfonic acid ester derivatives (2–4) were synthesized.
You Peng, Yaning Shi, Hua Zhang, Yoshinori Mine, Rong Tsao   +4 more
doaj  

Isoflavone content and antioxidant properties of soybean seeds [PDF]

, 2011
The isoflavone content and antioxidant properties of five Croatian soybean seed cultivars from two locations were analysed. The content of total and individual isofavones was determined by high performance liquid chromatography.
Edina Šertović, I. Mujić, Jelena Živković, Senka Vidović, Stela Jokić, Vildana Alibabić, Z. Sarić   +6 more
core   +3 more sources

Comparative effect of genistein and daidzein on the expression of MCP-1, eNOS, and cell adhesion molecules in TNF-α-stimulated HUVECs [PDF]

, 2011
We compared the effects of genistein and daidzein on the expression of chemokines, cell adhesion molecules (CAMs), and endothelial nitric oxide synthase (eNOS) in tumor necrosis factor (TNF)-α-stimulated human umbilical vascular endothelial cells (HUVECs)
Adamson, Anthony, Anthony, Berliner, Bingham, Bowie, Chen, Chung Mu Park, Chung Won Cho, D'Agostino, Dignam, Fautz, Gottstein, Guo, Hye Yeon Cho, Kapiotis, Kim, Kirk, Lee, Lee, Lee, Libby, Liu, Lund, Mahn, Majewska, May, Mi Jeong Kim, Mizutani, Radnaabazar Chinzorig, Rimbach, Ruiz-Larrea, Sadowska-Krowicka, Sheu, Si, Tetsuka, Vera, Weber, Wei, Woodman, Yen, Young Sun Song   +41 more
core   +2 more sources

Polyphenol Intake During Pregnancy and Childhood Asthma and Atopic Disorders: A Systematic Review

Clinical &Experimental Allergy, EarlyView.
Rachel J. Morgan, Cassidy Du Berry, Martin O'Hely, Lawrence Gray, Sarath Ranganathan, Peter Vuillermin, Peter D. Sly   +6 more
wiley   +1 more source

The Phenolic Signature of Psidium cattleianum Fruits and Leaves Modulates TRPV1 and TRPA1 Transient Receptor Potential Channels: A Metabolomics, In Vitro, and In Silico Study

Food Science &Nutrition, Volume 13, Issue 4, April 2025.
An untargeted metabolomics study was performed to find the encompassed phytochemicals in the fruit and leaf extract of Psidium cattleianum. This enabled the annotation of 469 compounds belonging to different phenolic subclasses, with a predominance of flavonoids and phenolics.
Leilei Zhang, Fabio Arturo Iannotti, Fatema R. Saber, Reem K. Arafa, Aniello Schiano Moriello, Rasha A. Rasle, Anton Soria‐Lopez, Sara G. Abd EL‐Gawwad, Gabriele Rocchetti, Paz Otero, Łukasz Kulinowski, Krystyna Skalicka‐Woźniak, Luigi Lucini, Jesus Simal‐Gandara   +13 more
wiley   +1 more source