Novel 2-amino-isoflavones exhibit aryl hydrocarbon receptor agonist or antagonist activity in a species/cell-specific context [PDF]
The aryl hydrocarbon receptor (AhR) mediates the induction of a variety of xenobiotic metabolism genes. Activation of the AhR occurs through binding to a group of structurally diverse compounds, most notably dioxins, which are exogenous ligands ...
BALBONI, GIANFRANCO +10 more
core +1 more source
Effect of daidzein on Parkinson disease induced by reserpine in rats
Parkinson disease is a neurodegenerative disorder characterised by the cardinal symptoms of stiffness, resting tremor, slowness (bradykinesia) and reduction of movement (hypokinesia).
Radha Goel, Rabia Chaudhary
doaj +1 more source
This study employs an interpretable machine learning framework to predict diabetes‐cancer comorbidity, with the Random Forest and LightGBM models demonstrating exceptional performance. SHAP value analysis reveals that while advanced age and cardiometabolic dysfunctions serve as primary risk drivers, dietary antioxidants (particularly daidzein and ...
Ming Xu +8 more
wiley +1 more source
Puerariae Radix and Hovenia Seed were co‐fermented with Lactiplantibacillus plantarum and Lacticaseibacillus paracasei to produce PHF. In a mouse model of alcohol‐induced liver injury, PHF intervention alleviated liver damage. The underlying mechanism may be related to the regulation of macrophage polarization.
Yunpeng Sun +7 more
wiley +1 more source
Effects of High-Dose Daidzein on Laying Performance, Egg Quality and Antioxidation in Laying Hens
This trial was conducted to evaluate the effects of high-dose daidzein supplements on laying performance, egg quality and antioxidation in laying hens during the late laying period. Seven hundred sixty eight 55-wk-old Hyline Brown were randomly assigned
Juan Cai +3 more
doaj +1 more source
Isoflavone Daidzein: Chemistry and Bacterial Metabolism
Isoflavone daidzein is a phytoestrogen widely distributed in Leguminosae and is especially rich in the soybean. The C6-C3 (rings B and C) unit of isoflavones is derived from the phenylpropanoid pathway and the remaining C6 (ring A) unit is from the polyketide pathway.
Mi-Hyang Kim, Jae-Hong Han, Soo-Un Kim
openaire +1 more source
Effect of forage legumes on feed intake, milk production and milk quality – a review [PDF]
Literature data from experiments with lactating dairy cows offered silage-based diets was reviewed to evaluate the effects of the grassland legume species Trifolium repens (WC, white clover), Trifolium pratense (RC, red clover) and Medicago sativa (M ...
Steinshamn, Håvard
core
Plasma equol concentration is not associated with breast cancer and fibrocystic breast conditions among women in Shanghai, China [PDF]
Equol (a bacterial metabolite of the soy isoflavone daidzein) is produced by 30% to 50% of humans and may be associated with health outcomes. We hypothesized that plasma equol would be inversely associated with risks of fibrocystic breast conditions (FBC)
Charlotte Atkinson +56 more
core +1 more source
Lipid‐Based Nanoparticles for Time‐Release Delivery of Flavonoids
Lipid‐based nanocarriers enhance the stability, bioavailability, and controlled release of flavonoids. These systems improve encapsulation efficiency and protection against degradation, highlighting their potential for food and nutraceutical applications.
Ziane da Conceição das Mercês +3 more
wiley +1 more source
Comparison of the toxicokinetics of daidzein and bisphenol A in pregnant and non-pregnant DA/Han rats [PDF]
Potentially adverse human and environmental effects due to hormone mimicry of environmental estrogens are a matter of current concern. Environmental estrogens belong to the socalled endocrine active compounds (EAC) and may alter signalling processes of ...
Degen, Gisela H., Selinski, Silvia
core

