Results 221 to 230 of about 8,364,200 (274)

NCOA4 Accelerates Abdominal Aortic Aneurysm Formation by Regulating Macrophage Activation and Ferroptosis via STAT1–CH25H Axis

Advanced Science, EarlyView.
Under pathological stimulation, NCOA4 in macrophages interacts with STAT1 to promote CH25H transcription. The subsequent increase in 25‐HC production activates macrophages, triggers inflammatory responses and ferroptosis, and accelerates the progression of AAA.
Zhinan Wu, Yuxuan Qian, Wenyi Xu, Fei Liao, Xueliang Liu, Xiao Kuang, Guqing Luo, Xinjie He, Lixian Jiang, Song Ding   +9 more
wiley   +1 more source

Transient neonatal hypothyroidism due to maternal seaweed soup ingestion: a report of 3 cases. [PDF]

JCEM Case Rep
Ilmer S, Lopez-Cabreza V, Salemi P.
europepmc   +1 more source

EphB1 Receptor Blockade Augments Morphine Antinociception via Inhibiting GRK2‐Mediated µ‐Opioid Receptor Internalization

Advanced Science, EarlyView.
Administration of opioids activates ephrinB2‐EphB1 receptor signaling. Activated EphB1 receptors induce GRK2‐mediated phosphorylation of MOR at Ser375, which initiates the internalization of MOR and reduces opioid antinociception at the behavioral level. ABSTRACT Opioids are the primary treatment for severe pain in clinical practice.
Bo Peng, Xiaqing Lin, Hongyu Yao, Cheng Li, Huabao Liao, Yuexin Liu, Boxu Cao, Xue‑Jun Song   +7 more
wiley   +1 more source

Navepegritide in children with achondroplasia. [PDF]

Transl Pediatr
Semler O, Hoyer-Kuhn H.
europepmc   +1 more source

Thyroxine binding globulin deficiency due to a novel <i>HNF1B</i> gene variant in a young girl with high thyroxine requirement. [PDF]

JCEM Case Rep
Manasa CVS, Bora A, A V Alekya L, Mashetty S, Guddeti A, Hari Kumar KVS.   +5 more
europepmc   +1 more source

Injection-site pain after switching from somatrogon to somapacitan in children reporting pain or discomfort during once-weekly growth hormone therapy: a prospective single-arm switch study. [PDF]

Front Endocrinol (Lausanne)
Iwayama H, Kawahara K, Kitagawa S, Miyamoto R, Takagi J, Ito Y, Okumura A.   +6 more
europepmc   +1 more source

Late-onset atypical pseudohypoparathyroidism type 1A with intracranial calcification and epilepsy associated with a novel <i>GNAS</i> variant: a case report. [PDF]

Front Endocrinol (Lausanne)
Hua D, Xiang S, Yu X, Wu J, Wang Y, Yang W, Wang H.   +6 more
europepmc   +1 more source