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Association of Daily Growth Hormone Injection Adherence and Height Among Children With Growth Hormone Deficiency

Endocrine Practice, 2022
Recombinant human growth hormone (somatropin) is recommended for children with growth hormone deficiency (GHD) to normalize adult height. Prior research has indicated an association between adherence to somatropin and height velocity. Further research is needed using real-world data to quantify this relationship; hence the objective of this study was ...
Bradley Miller, Priti Jhingran
exaly   +3 more sources

Suboptimal adherence to daily growth hormone in a US real-world study: an unmet need in the treatment of pediatric growth hormone deficiency [PDF]

open access: yesCurrent Medical Research and Opinion, 2021
To evaluate adherence to, and discontinuation of, somatropin treatment over 4 years in a US population-based study of children with pediatric growth hormone deficiency (pGHD).A retrospective cohort analysis of commercially insured patients ≥3 and 3, 12, 24, 36, and 48 months of post-index continuous enrollment).
Michael P Wajnrajch
exaly   +3 more sources

Daily Subcutaneous Administration of Human Growth Hormone in Growth Hormone Deficient Children

Acta Paediatrica, International Journal of Paediatrics, 1986
ABSTRACT Sixteen children (10 boys, 6 girls) on treatment for some years with i.m. injections twice or thrice weekly of human growth hormone (hGH; Crescormon® KabiVitrum), participated in a prospective study. The weekly amount of hGH (8, 12, or 16 IU) was kept the same in each child, but divided into daily (7) s.c. injections at bedtime.
Kerstin Albertsson-Wikland   +2 more
exaly   +3 more sources

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