Results 131 to 140 of about 1,392,331 (344)
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
New Damage Accumulation Model for Spall Propagation Mechanism in Bearing Raceways. [PDF]
Materials (Basel), 2023 Ohana R, Klein R, Shneck R, Bortman J.
europepmc +1 more source
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Study on the Residual Strength of Nonlinear Fatigue-Damaged Pipeline Structures
Applied SciencesThe heat alternation and bending during the service process of the pipeline structure are the key issues affecting its residual strength. The nonuniform plastic deformation of its cross-section causes nonlinear damage to the structure, which makes it ...
Wenlan Wei +5 more
doaj +1 more source
Dynamic Response and Damage Accumulation of Laminated Composites under Repeated Low-Velocity Impacts. [PDF]
Materials (Basel), 2023 Sun J, Huang L, Dai Y.
europepmc +1 more source
Characterization of failure processes in tungsten copper composites under fatigue loading conditions [PDF]
A fractographic and metallographic investigation was performed on specimens of a tungsten fiber reinforced copper matrix composite (9 vol percent), which had experienced fatigue failures at elevated temperatures.
Gabb, Timothy P. +2 more
core +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Non-Linear Probabilistic Modification of Miner's Rule for Damage Accumulation. [PDF]
Materials (Basel), 2021 Blacha Ł.
europepmc +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Recent Advances in Limiting Fatigue Damage Accumulation Induced by Self-Heating in Polymer-Matrix Composites. [PDF]
Polymers (Basel), 2022 Amraei J, Katunin A.
europepmc +1 more source