Results 101 to 110 of about 1,891,292 (305)

Vibration based Structural Health Monitoring of a Composite Plate Structure with Multiple Stiffeners [PDF]

open access: yes, 2010
A vibration based damage identification method is investigated experimentally.\ud The dynamic response of an intact and a locally damaged 16–layer unidirectional\ud carbon fibre PEKK reinforced plate structure with two stiffener sections is considered ...
Akkerman, R.   +4 more
core   +2 more sources

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

A Leafhopper Pest of Plants in the Mint Family, Eupteryx decemnotata Rey (Hemiptera: Auchenorrhyncha: Cicadellidae), Ligurian Leafhopper, New to North America [PDF]

open access: yes, 2009
The Ligurian leafhoppter, Eupteryx decemnotata Rey (Hemiptera: Auchenorrhyncha: Cicadellidae), is reported for the first time in North America (USA: Florida and California).
Gill, Raymond J.   +3 more
core  

Model coupling friction and adhesion for steel-concrete interfaces

open access: yes, 2009
The interface behaviour between steel and concrete, during pull-out tests, is numerically investigated using an interface model coupling adhesion and Coulomb friction. This model, first developed by Raous, Cang\'emi, Cocou and Monerie (RCCM), is based on
Karray, M'hamed Ali, Raous, Michel
core   +3 more sources

Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells

open access: yesFEBS Letters, EarlyView.
Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López   +2 more
wiley   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Comparative Analysis of Fractals-Homogeneity-Entropy Algorithms Applied on a FEM Bridge Model to Identify Damage

open access: yesInfrastructures
Vehicular bridges accumulate damage over time due to overloads and material degradation. Non-visible structural damage in such large structures poses a serious risk, as small defects in critical elements can rapidly grow, potentially leading to ...
Jose M. Machorro-Lopez   +3 more
doaj   +1 more source

Identification of Ultimate DNA Damaging Oxygen Species

open access: yesEnvironmental Health Perspectives, 1990
DNA damage induced by various reactive oxygen species can be characterized using a set of repair endonucleases with defined substrate specificities. DNA damage profiles thus obtained in a cell-free system can be compared with those observed in cellular DNA.
B, Epe, J, Hegler, D, Wild
openaire   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

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