Results 101 to 110 of about 1,741,299 (263)

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

open access: yesFEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai   +9 more
wiley   +1 more source

Assessing the Suitability of Damage Indexes for Digital Twin Applications in RC Buildings Considering Masonry Infills

open access: yesApplied Sciences
Given the significant damage caused by earthquakes over the years, accurate prediction and assessment of the extent of structural damage is critical to ensure safety and guide post-disaster recovery efforts.
Luca Danesi   +3 more
doaj   +1 more source

A simplified model for evaluation of fatigue damage in frames [PDF]

open access: yes, 1998
Many studies have been developed to analyze the structural seismic behavior through the damage index concept. The evaluation of this index has been employed to quantify the safety of new and existing structures and, also, to establish a framework for ...
Alarcón Álvarez, Enrique   +2 more
core  

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

Penggunaan Mean Damage Index (Mdi) dalam Mengkaji Kerusakan Morfologi Benthos yang Tertangkap dengan Alat Tangkap Garok [PDF]

open access: yes, 2008
Tujuan dari penelitian ini adalah untuk mengkaji penggunaan Mean Damage Index (MDI) yang diperkenalkan Jensen et al. (2001) dalam menilai kerusakan morfologis yang ditimbulkan alat tangkap garok terhadap makrozoobenthos.
Farmelia, E. O. (Estri)   +2 more
core  

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Characterizing the Phytotoxic Effects of Hydrogen Peroxide on Common Microgreen Species and Lettuce Cultivars

open access: yesHortTechnology, 2019
Hydrogen peroxide (H2O2) is an oxidizing agent used to disinfect recirculated irrigation water during the production of organic crops under controlled environmental systems (e.g., greenhouses).
Mitchell Eicher-Sodo   +2 more
doaj   +1 more source

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

Dynamic characterisation of a damaged composite structure with stiffeners employing fibre bragg gratings [PDF]

open access: yes, 2011
One of the key issues in composite structures for aircraft applications is the early detection and localisation of damage. Often service induced damage does not involve visible plastic deformation, but internal matrix related damage, like transverse ...
Akkerman, R.   +5 more
core   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

open access: yesFEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura   +2 more
wiley   +1 more source

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