Results 231 to 240 of about 1,741,299 (263)

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

Relationship between ultrasound damage score of peripheral entheses and spinal bone formation in long-standing radiographic axial spondyloarthritis. [PDF]

RMD Open
Deminger A, Geijer M, Hallström M, Jacobsson LTH, Forsblad-d'Elia H.   +4 more
europepmc   +1 more source

Digital twins to accelerate target identification and drug development for immune‐mediated disorders

FEBS Open Bio, EarlyView.
Digital twins integrate patient‐derived molecular and clinical data into personalised computational models that simulate disease mechanisms. They enable rapid identification and validation of therapeutic targets, prediction of drug responses, and prioritisation of candidate interventions.
Anna Niarakis, Philippe Moingeon
wiley   +1 more source

Combined 5‐aminolevulinic acid and ferric ammonium citrate treatment promotes hair follicle growth by activating dermal papilla cells

FEBS Open Bio, EarlyView.
5‐Aminolevulinic acid combined with ferric ammonium citrate (5‐ALA/FAC) stimulates dermal papilla cell activity and promotes hair follicle growth. The treatment enhances ERK and AKT signaling, increases hair‐inductive gene expression, and restores dermal papilla function suppressed by dihydrotestosterone and oxidative stress, resulting in enhanced hair
Han‐Wook Ryu, Eok‐Soo Oh, Sewoon Kim
wiley   +1 more source

Evolutionarily divergent DUF4465 domains have a common vitamin B12‐binding function

FEBS Open Bio, EarlyView.
We show that DUF4465 family proteins, widespread across bacteria from gut microbiomes, hydrothermal vents, and soil, share a common vitamin B12‐binding function. These augmented β‐jellyroll proteins bind vitamin B12 via extended loops. Our findings establish sequence‐diverse DUF4465 proteins as a widespread class of B12‐binding proteins, highlighting ...
Charlea Clarke, Michal Banasik, Rokas Juodeikis, Martin J. Warren, Richard W. Pickersgill   +4 more
wiley   +1 more source

The Effect of Cranio-Cervical Artery Stenosis on Glymphatic System Function in Patients with Cerebral Infarction. [PDF]

J Clin Med
Liu X, Qiao H, Li C, Zhang X, Gao Y, Song M, Wang Y, Yang Y.   +7 more
europepmc   +1 more source

Follow-up of jaundice-free biliary atresia survivors using M2BPGi and APRI in a local hospital. [PDF]

World J Pediatr Surg
Shirai T, Okuya S.
europepmc   +1 more source

Association between the triglyceride-glucose index and vascular damage among community residents in Yunnan, China. [PDF]

BMC Endocr Disord
Zhu W, Zhang N, Xia Y, Zhu R, Shi W, Duo L, Tang M, Zhu D.   +7 more
europepmc   +1 more source

Quantitative thermal indices in infrared imaging as auxiliary tool in the diagnosis of peripheral artery disease and diabetic peripheral neuropathy among patients with type 2 diabetes. [PDF]

Oxf Med Case Reports
Ortiz-Sosa R, Serrano-Loyola R, Fuentes-Oliver EI, García-Segundo C.   +3 more
europepmc   +1 more source